ABSTRACT
Background The primary factor associated with fatality in thalassemia patients is heavy cardiac complications. Currently, magnetic resonance imaging (MRI) is accepted as the non-invasive modality of choice for diagnosing iron overload in the liver. This study aimed to correlate liver iron concentration (LIC) and myocardium iron concentration (MIC) determined by MRI and clinical and biochemical parameters in non-transfusion-dependent thalassemia (NTDT) patients. Methodology This prospective study was conducted in the radiology department from October 2016 to September 2018. A total of 30 patients were included. Using Siemens MAGNETOM® Avanto 1.5T, iron was quantified with a body matrix coil. Sequences performed were gradient-echo 8 and 12 for the myocardium and liver, respectively. Dual-echo fast spoiled gradient-echo in/out phase and diffusion-weighted images were used. Iron values were calculated using T2* spreadsheet analysis software version 3.1. Data were analyzed using coGuide software V.1.03. Results The mean age of the participants was 24.9 ± 12.6 years. There was a very strong positive correlation between LIC and serum ferritin. There was a strong negative correlation between LIC and hemoglobin. Between LIC and MIC, there was a marginally favorable relationship (rs value = 0.077, p-value = 0.985). Conclusions When MRI is not available, serum ferritin can be used as an alternative to diagnose iron overload in patients with NTDT.
ABSTRACT
BACKGROUND: Postoperative sensitivity after temporization is a common complaint in Fixed Partial Denture patients. It is caused by weak and ill fitting temporary restorations which results in microleakage. This can be controlled by providing good temporary restorations and by coating the exposed dentinal tubules of the prepared tooth with dentin bonding agent or dental varnish. AIM: The purpose of the study was to determine the effect of dentin-bonding, dentin sealing agents on the microleakage of temporary crowns made by tooth colored auto polymerizing resin fabricated with direct and indirect technique. MATERIALS AND METHODS: Thirty premolar and molar human teeth were collected which were extracted recently was used for the study. The teeth were marked and divided into 3 groups each containing 10 nos. They were individually mounted with self-cure acrylic resin. It was then mounted on a milling machine and crown preparations done. Temporary crowns were fabricated by direct and indirect method with two types of materials. In group A (Control group), the temporary crowns fabricated with both direct and indirect method were cemented directly with temporary luting cement. In group B dentine-bonding agent (solobond M) was applied once to the prepared surface of each tooth specimen before the cementation of temporary crowns where as in case of group C a single layer of dental varnish is applied prior to crown cementation. The entire specimens were immersed in 1% methylene blue and allowed to undergo thermal treatment. It was then sectioned in a hard tissue microtome. Each section was evaluated for dye penetration into the dentin tubules by comparing it with a visual scale. STATISTICAL ANALYSIS: SPSS Version 13 software was used for non-parametric data analysis by a qualified statistician. P-values less than 0.05 (p-value<0.05) were considered to be statistically significant. RESULTS: Group B (Dentin Bonding Agent) specimens cemented with crowns fabricated in direct technique showed the least amount of microleakage when compared with group A and group C. Group C (Dental Varnish) specimen showed comparatively more amount of microleakage than that of group B. Group A (control group) specimens showed the maximum amount of microleakage. CONCLUSION: The application of a single layer of Dental varnish appears to be of no significant benefit when compared to crowns cemented with the application of Dentin bonding agent on the tooth surface. The application of a single layer of Dentin bonding agent (Solobond M) and temporary crowns fabricated with direct technique may be of some benefit for crown preparations as an interim measure prior to the luting of final crown.
ABSTRACT
UNLABELLED: Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis. PURPOSE: To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins. MATERIALS AND METHODS: Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h. RESULTS: Group D showed multifold decrease in the colony-forming units. CONCLUSION: The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.
