Ethical Considerations from Child-Robot Interactions in Under-Resourced Communities.

Recent advancements in socially assistive robotics (SAR) have shown a significant potential of using social robotics to achieve increasing cognitive and affective outcomes in education. However, the deployments of SAR technologies also bring ethical challenges in tandem, to the fore, especially in under-resourced contexts. While previous research has highlighted various ethical challenges that arise in SAR deployment in real-world settings, most of the research has been centered in resource-rich contexts, mainly in developed countries in the 'Global North,' and the work specifically in the educational setting is limited. This research aims to evaluate and reflect upon the potential ethical and pedagogical challenges of deploying a social robot in an under-resourced context. We base our findings on a 5-week in-the-wild user study conducted with 12 kindergarten students at an under-resourced community school in New Delhi, India. We used interaction analysis with the context of learning, education, and ethics to analyze the user study through video recordings. Our findings highlighted four primary ethical considerations that should be taken into account while deploying social robotics technologies in educational settings; (1) language and accent as barriers in pedagogy, (2) effect of malfunctioning, (un)intended harms, (3) trust and deception, and (4) ecological viability of innovation. Overall, our paper argues for assessing the ethical and pedagogical constraints and bridging the gap between non-existent literature from such a context to evaluate better the potential use of such technologies in under-resourced contexts.

Molecular Characterization of the pol Gene of Vertically Transmitted HIV-1 Strains in Children with Virological Failure.

HIV-1 pol gene sequences were analyzed from 77 HIV-1 positive children infected perinatally and exhibiting virological failure (VF). Viral subtyping, phylogenetic analysis, and genotypic drug resistance analysis were carried out on samples collected before start of anti retroviral treatment (ART) (baseline, BL), and at 12 months post-ART initiation (M12). Subtype C was found to be most predominant, seen in 75 of the 77 (97.4%) children. The level of pretreatment drug resistance (PDR) was 14% among these children. At BL, K103N (5), E138A/G (4), and M184V (3) were the most common mutations. At M12 the prevalence of any resistance-associated mutation (RAM) (acquired drug resistance/ADR) was 81.8% (63/77). Dual class resistance mutations were seen in 64% (49/77) of children. M184V/I, K103N/S, and Y181C were the most commonly occurring mutations, seen in 76%, 51%, and 36% children. RAMs to the second-generation non-nucleoside reverse transcriptase inhibitors (NNRTI), etravirine (ETR) and rilpivirine (RPV), were seen in 40.2% (31/77) and 48.05% (37/77) of the children, respectively. Our findings reveal similar prevalence rates of PDR and ADR in children with VF as reported in other studies. Occurrence of ETR and RPV resistance associated mutations (RAMs) is of concern and highlights the need for timely switch of regimens guided by genotypic resistance testing in perinatally infected children from India.

Critical current fluctuations in graphene Josephson junctions.

We have studied 1/f noise in critical current [Formula: see text] in h-BN encapsulated monolayer graphene contacted by NbTiN electrodes. The sample is close to diffusive limit and the switching supercurrent with hysteresis at Dirac point amounts to [Formula: see text] nA. The low frequency noise in the superconducting state is measured by tracking the variation in magnitude and phase of a reflection carrier signal [Formula: see text] at 600-650 MHz. We find 1/f critical current fluctuations on the order of [Formula: see text] per unit band at 1 Hz. The noise power spectrum of critical current fluctuations [Formula: see text] measured near the Dirac point at large, sub-critical rf-carrier amplitudes obeys the law [Formula: see text] where [Formula: see text] and [Formula: see text] at [Formula: see text] Hz. Our results point towards significant fluctuations in [Formula: see text] originating from variation of the proximity induced gap in the graphene junction.

Multi-platform optical remote sensing dataset for target detection.

Target detection in remote sensing has vital applications in mineral mapping, law enforcement, precision agriculture, strategic surveillance, etc. We present the acquisition of a first-of-its-kind high-resolution multi-platform (ground, airborne, and space-borne) remote sensing-based benchmark dataset for target detection studies. The dataset includes imagery acquired from terrestrial hyperspectral imager (THI), airborne hyperspectral sensor (AVIRIS-NG), and space-borne multi-spectral (Sentinel-2) sensor on 20th March 2018. Five engineered targets of different materials and colours were placed on different surface backgrounds. Besides, in-situ reflectance spectra of the targets were also acquired using a spectroradiometer for serving as a spectral reference source. The airborne and space-borne imagery were processed to remove un-calibrated/noisy bands and were atmospherically corrected using a radiative transfer method based Fast Line-of-sight Atmospheric Analysis of Spectral Hypercubes (FLAASH) model. The in-situ target reflectance spectra were resampled to spectrally match with airborne and space-borne imagery. Further, a target region of interest (ROI) was designated for each of the targets in both airborne and space-borne imagery using the known ground position of targets using a GPS device. This article provides a ground to space integrated target detection dataset, including ground positions ROI of the targets, point, and pixel-based in-situ target reference spectra, and the processed airborne and space-borne imagery to make the dataset ready for use. The data acquired in this experiment is an attempt to assess the potential of engineered material target detection in a multi-scale multi-platform view setup. The dataset is a valuable resource for testing and validation of target detection algorithms from various strategic and civilian application perspectives of remote sensing.

Unconventional fractional quantum Hall states and Wigner crystallization in suspended Corbino graphene.

Competition between liquid and solid states in two-dimensional electron systems is an intriguing problem in condensed matter physics. We have investigated competing Wigner crystal and fractional quantum Hall (FQH) liquid phases in atomically thin suspended graphene devices in Corbino geometry. Low-temperature magnetoconductance and transconductance measurements along with IV characteristics all indicate strong charge density dependent modulation of electron transport. Our results show unconventional FQH phases which do not fit the standard Jain's series for conventional FQH states, instead they appear to originate from residual interactions of composite fermions in partially filled Landau levels. Also at very low charge density with filling factors [Formula: see text], electrons crystallize into an ordered Wigner solid which eventually transforms into an incompressible Hall liquid at filling factors around ν ≤ 1/7. Building on the unique Corbino sample structure, our experiments pave the way for enhanced understanding of the ordered phases of interacting electrons.

Gyrotropic Zener tunneling and nonlinear IV curves in the zero-energy Landau level of graphene in a strong magnetic field.

We have investigated tunneling current through a suspended graphene Corbino disk in high magnetic fields at the Dirac point, i.e. at filling factor ν = 0. At the onset of the dielectric breakdown the current through the disk grows exponentially before ohmic behaviour, but in a manner distinct from thermal activation. We find that Zener tunneling between Landau sublevels dominates, facilitated by tilting of the source-drain bias potential. According to our analytic modelling, the Zener tunneling is strongly affected by the gyrotropic force (Lorentz force) due to the high magnetic field.

Fast and accurate shot noise measurements on atomic-size junctions in the MHz regime.

Shot noise measurements on atomic and molecular junctions provide rich information about the quantum transport properties of the junctions and on the inelastic scattering events taking place in the process. Dissipation at the nanoscale, a problem of central interest in nano-electronics, can be studied in its most explicit and simplified form. Here, we describe a measurement technique that permits extending previous noise measurements to a much higher frequency range, and to much higher bias voltage range, while maintaining a high accuracy in noise and conductance. We also demonstrate the advantages of having access to the spectral information for diagnostics.

Screening for probiotic properties of strains isolated from feces of various human groups.

The present study searched for potential probiotic strains from various human fecal samples. A total of 67 aerobic and 38 anaerobic strains were isolated from 5 different categories of human feces. Systematic procedures were used to evaluate the probiotic properties of the isolated strains. These showed about 75-97% survivability in acidic and bile salt environments. Adhesion to intestinal cell line Caco-2 was also high. The isolates exhibited hydrophobic properties in hexadecane. The culture supernatants of these strains showed antagonistic effects against pathogens. The isolates were resistant to a simulated gastrointestinal environment in vitro. Of the 4 best isolates, MAbB4 (Staphylococcus succinus) and FIdM3 (Enterococcus fecium), were promising candidates for a potential probiotic. S. succinus was found to be a probiotic strain, which is the second such species reported to date in this particular genus. A substantial zone of inhibition was found against Salmonella spp., which adds further support to the suggestion that the probiotic strain could help prevent intestinal infection. This study suggested that the human flora itself is a potential source of probiotics.

Detection of vibration-mode scattering in electronic shot noise.

We present shot noise measurements on Au nanowires showing very pronounced vibration-mode features. In accordance to recent theoretical predictions the sign of the inelastic signal, i.e., the signal due to vibration excitations, depends on the transmission probability becoming negative below a certain transmission value. We argue that the negative contribution to noise arises from coherent two-electron processes mediated by electron-phonon scattering and the Pauli exclusion principle. These signals can provide unique information on the local phonon population and lattice temperature of the nanoscale system.

Association of C3435T multi drug resistance gene-1 polymorphism with aspirin resistance in ischemic stroke and its subtypes.

Aspirin is the most commonly used antiplatelet drug for treatment of a serious vascular event, most notably myocardial infarction and stroke. Significant fraction of aspirin treated patients is resistant to the antiplatelet effects of the drugs. Previous studies have suggested that a genetic basis for aspirin resistance exists. Therefore the present study was taken up to investigate the role of C3435T polymorphism (rs 1045642) of multiple drug resistance-1 (MDR-1) gene with aspirin resistance in stroke patients. Five hundred and sixty ischemic stroke patients and 560 age and sex matched healthy controls were involved in the study. Baseline clinical data were collected and follow-up telephone interviews were conducted with patients at 3, 6 and 12 months post event to determine stroke outcome. Blood samples were collected and genotypes determined. Significant difference was observed in the genotype distribution and allele frequency between patients and controls. The results were confirmed by a step wise multiple logistic regression analysis controlling all other confounding risk factors [adjusted Odds ratio=3.132 (95% CI; 2.043-4.800; p<0.001)]. There was a significant difference in genotype distribution between drug responders and non-responders. The risk of aspirin resistance was significantly high in patients with TT genotype in comparison to those with CC genotype [(TT vs. CC, χ(2)=6.268; p=0.012, Odds ratio=1.85) (95% CI; 1.142-3.017) (adjusted Odds ratio=2.465; 95% CI; 1.895-4.625 and p<0.001)]. As far as the stroke subtypes are concerned TT genotype associated significantly with aspirin resistance in intracranial large artery atherosclerosis. Our results indicate that the risk of aspirin resistance is more in patients with 3435TT genotype than in those with CC genotype. However, this is a preliminary study and a large study of replication is needed to confirm our results.