Subject(s)
Diabetes Mellitus , Nurse Practitioners , Physician Assistants , Physicians , Cohort Studies , HumansSubject(s)
Thiamine/supply & distribution , Drug Industry , Humans , Orphan Drug Production , United StatesABSTRACT
Squamous cell carcinoma of the head and neck is a rare cause of humoral hypercalcemia of malignancy. This paraneoplastic syndrome is usually one of the presenting symptoms of the disease. We report a case of squamous cell carcinoma of the oral cavity that presumably elaborated parathyroid hormone-related peptide (PTH-rP) and caused hypercalcemia only after radiotherapy and chemotherapy.
Subject(s)
Carcinoma, Squamous Cell/metabolism , Hypercalcemia , Mouth Neoplasms/metabolism , Paraneoplastic Endocrine Syndromes , Proteins/metabolism , Aged , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/therapy , Female , Humans , Hypercalcemia/etiology , Mouth Neoplasms/pathology , Mouth Neoplasms/therapy , Paraneoplastic Endocrine Syndromes/etiology , Parathyroid Hormone-Related Protein , Radiotherapy/adverse effectsABSTRACT
Mycoplasma pneumoniae pneumonia can be associated with several systemic features. This report illustrates a case of M. pneumoniae pneumonia in an adult who recovered completely. Direct infection of the kidneys or an immunologic mechanism may have been the underlying cause. This patient also had simultaneous pharyngitis caused by group A beta-hemolytic streptococci. Various clinical possibilities with respect to pneumonia, pharyngitis, and proteinuria are briefly reviewed.
