1.
Org Biomol Chem
; 15(35): 7330-7338, 2017 Sep 13.
Article
in English
| MEDLINE
| ID: mdl-28828454
ABSTRACT
A highly effective oxidative thiyl radical addition/cyclization of N-methacryloylbenzamides was explored using dioxygen as the sole terminal oxidant without the use of precious and/or toxic transition-metal catalysts. This method provides convenient access to a variety of useful sulfide-containing 4,4-disubstituted isoquinoline-1,3-diones by constructing C-S and C-C bonds in one step.