ABSTRACT
Osteosarcoma of the jaw bone is comparatively rare and accounts for about 6.5% of all osteosarcomas. We treated eight cases of osteosarcoma of the jaw bone involving the mandible and maxilla in equal proportions between 1986-1992. The median age was 31 years and male: female ratio was 5:3. Swelling and bony expansion were the most common presentations. Radiologically six patients had lytic lesions, and histopathologically they were osteoblastic (n = 4), chondroblastic (n = 3) and fibroblastic (n = 1). Three patients, two with mandibular and one with maxillary osteosarcoma underwent radical surgery and six courses of cisplatinum-based chemotherapy. All were alive and disease free 24, 30, and 54 months after treatment. Histologically all three were chondroblastic. Five patients had incomplete or palliative treatment. All patients died of progressive or locally recurrent disease within 2 years.
Subject(s)
Mandibular Neoplasms/therapy , Maxillary Neoplasms/therapy , Osteosarcoma/therapy , Adult , Antineoplastic Agents/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cause of Death , Chondrocytes/pathology , Cisplatin/administration & dosage , Combined Modality Therapy , Disease-Free Survival , Female , Fibroblasts/pathology , Follow-Up Studies , Humans , Male , Mandibular Neoplasms/diagnostic imaging , Mandibular Neoplasms/pathology , Maxillary Neoplasms/diagnostic imaging , Maxillary Neoplasms/pathology , Neoplasm Recurrence, Local/pathology , Osteoblasts/pathology , Osteolysis/diagnostic imaging , Osteosarcoma/diagnostic imaging , Osteosarcoma/pathology , Osteotomy , Palliative Care , Radiography , Retrospective StudiesABSTRACT
Oral Metastasis from a carcinoma of the urinary Bladder is extremely uncommon. Two cases of transitional cell carcinoma of the Bladder, presenting eighteen and ten months after initial diagnosis, one with soft tissue metastasis in the upper alveolus and the other with bony metastasis to the mandible are discussed.
