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Bull Environ Contam Toxicol ; 95(2): 164-70, 2015 Aug.
Article in English | MEDLINE | ID: mdl-25726008

ABSTRACT

Changes in the blood parameters of fingerlings of Clarias gariepinus were investigated after 24 and 96-h of exposures to endosulfan. 180 fingerlings of C. gariepinus [mean weight (10.5±1.3 g); total length (11.2±1.2 cm)] were exposed to five different concentrations (1.00, 2.20, 4.80, 11.00, 23.00 µg/L) of endosulfan and a control for 96 h after being acclimatized for 21 days. After 24 h of exposure, microcytic hypochromic anemia was observed and all erythrocyte profiles tested showed significant variation (p<0.05) among the treatments except thrombocyte and mean corpuscular hemoglobin concentration. Macrocytic hyperchromic anemia was noticed after 96 h of exposure and all the hematological parameters varied significantly (p<0.05) except packed cell volume and red blood cell count. The study shows that endosulfan alters the hematology of C. gariepinus fingerlings. Therefore, awareness on the hazards associated with the use of endosulfan should be intensified and sound sustainable alternatives to endosulfan should be developed.


Subject(s)
Anemia/chemically induced , Catfishes/blood , Endosulfan/toxicity , Erythrocytes/drug effects , Insecticides/toxicity , Animals , Erythrocyte Count , Erythrocyte Indices , Hematocrit , Hydrocarbons, Chlorinated
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