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Georgian Med News ; (130): 107-11, 2006 Jan.
Article in Russian | MEDLINE | ID: mdl-16510927

ABSTRACT

Influence of different doses of 4-nitrophenol on some biochemical and morphological indices of rat blood was studied. Glucose and beta-lipoprotein concentration increased, but total protein concentration decreased in response to intraperitoneal injection of xenobiotic. As a result of xenobiotic action, the total amount of leukocytes and thrombocytes increased, while the amount of erythrocytes decreased. The morphological study of structural indices of blood formed elements has demonstrated, that intensity of the defensive response of blood formed elements was 4-nitrophenol dose-dependent.


Subject(s)
Blood Glucose/metabolism , Environmental Illness/blood , Lipoproteins, LDL/blood , Nitrophenols/toxicity , Animals , Blood Glucose/drug effects , Blood Platelets/drug effects , Disease Models, Animal , Dose-Response Relationship, Drug , Environmental Illness/chemically induced , Erythrocytes/drug effects , Injections, Intraperitoneal , Leukocytes/drug effects , Lipoproteins, LDL/drug effects , Male , Nitrophenols/administration & dosage , Rats
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