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1.
Cardiovasc Intervent Radiol ; 36(4): 898-903, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23073561

ABSTRACT

Central venous occlusive disease (CVD) is a common concern among the hemodialysis patient population, with the potential to cause significant morbidity. Endovascular management of CVD, comprising percutaneous balloon angioplasty and bare-metal stenting, has been established as a safe alternative to open surgical treatment. However, these available treatments have poor long-term patency, requiring close surveillance and multiple repeat interventions. Recently, covered stents have been proposed and their efficacy assessed for the treatment of recalcitrant central venous stenosis and obstruction. Moreover, newly proposed algorithms for the surgical management of CVD warrant consideration. Here, we seek to provide an updated review of the current literature on the various treatment modalities for CVD.


Subject(s)
Catheterization, Central Venous/adverse effects , Endovascular Procedures/methods , Renal Dialysis/adverse effects , Stents , Vascular Access Devices/adverse effects , Catheterization, Central Venous/instrumentation , Constriction, Pathologic/diagnostic imaging , Constriction, Pathologic/therapy , Endovascular Procedures/instrumentation , Female , Humans , Incidence , Male , Phlebography/methods , Prognosis , Renal Dialysis/methods , Retreatment , Risk Assessment , Severity of Illness Index , Vascular Patency/physiology
2.
J Vasc Access ; 13(4): 464-7, 2012.
Article in English | MEDLINE | ID: mdl-22865527

ABSTRACT

PURPOSE: To assess the technical success rate and safety of radiofrequency perforation guidewire (RF) technology for the recanalization of refractory chronic central venous occlusions in symptomatic hemodialysis patients with failed conventional endovascular methods. METHODS: This single center retrospective cohort of hemodialysis patients comprised of six men (mean age 67 years, range 55 to 80) with autogenous fistulae, who had already undergone failed conventional endovascular methods. These patients underwent the RF perforation technique from December 2006 to January 2010. RESULTS: Three patients were successfully treated using the RF perforation technique, after which they had PTFE stent grafts placed at the site of occlusion. There was no recurrence of clinical symptoms. In the remaining three patients, the procedure was terminated after multiple unsuccessful attempts. There were no complications. CONCLUSIONS: The RF perforation technique is a potential alternative technology for recanalization of refractory chronic central venous occlusions in hemodialysis patients in the setting of failed conventional endovascular recanalization techniques.


Subject(s)
Angioplasty, Balloon , Arteriovenous Shunt, Surgical/adverse effects , Catheter Ablation/instrumentation , Renal Dialysis , Upper Extremity/blood supply , Vascular Access Devices , Vascular Diseases/surgery , Aged , Aged, 80 and over , Angioplasty, Balloon/adverse effects , Angioplasty, Balloon/instrumentation , Catheter Ablation/adverse effects , Constriction, Pathologic , Equipment Design , Humans , Male , Middle Aged , Ontario , Punctures , Reoperation , Retrospective Studies , Stents , Treatment Outcome , Vascular Diseases/diagnosis , Vascular Diseases/etiology , Vascular Diseases/physiopathology , Vascular Patency , Veins/physiopathology , Veins/surgery
5.
Cardiovasc Intervent Radiol ; 34(5): 949-57, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21069331

ABSTRACT

PURPOSE: To assess the safety and effectiveness of a polytetrafluoroethylene (PTFE) encapsulated nitinol stents (Bard Peripheral Vascular, Tempe, AZ) for treatment of hemodialysis-related central venous occlusions. MATERIALS AND METHODS: Study design was a single-center nonrandomized retrospective cohort of patients from May 2004 to August 2009 for a total of 64 months. There were 14 patients (mean age 60 years, range 50-83 years; 13 male, 1 female). All patients had autogenous fistulas. All 14 patients had central venous occlusions and presented with clinical symptoms of the following: extremity swelling (14%, 2 of 14), extremity and face swelling (72%, 10 of 14), and face swelling/edema (14%, 2 of 14). There was evidence of access dysfunction with decreased access flow in 36% (5 of 14) patients. There were prior interventions or previous line placement at the site of the central venous lesion in all 14 patients. Results were assessed by recurrence of clinical symptoms and function of the access circuit (National Kidney Foundation recommended criteria). RESULTS: Sixteen consecutive straight stent grafts were implanted in 14 patients. Average treated lesion length was 5.0 cm (range, 0.9-7 cm). All 14 patients had complete central venous occlusion (100% stenosis). The central venous occlusions were located as follows: right subclavian and brachiocephalic vein (21%, 3 of 14), right brachiocephalic vein (36%, 5 of 14), left brachiocephalic vein (36%, 5 of 14), and bilateral brachiocephalic vein (7%, 1 of 14). A total of 16 PTFE stent grafts were placed. Ten- or 12-mm-diameter PTFE stent grafts were placed. The average stent length was 6.1 cm (range, 4-8 cm). Technical (deployment), anatomic (<30% residual stenosis), clinical (resolution of symptoms), and hemodynamic (resolution of access dysfunction) success were 100%. At 3, 6, and 9 months, primary patency of the treated area and access circuit were 100% (14 of 14). CONCLUSIONS: This PTFE encapsulated stent graft demonstrates encouraging intermediate-term patency results for central vein occlusions. Further prospective studies with long-term assessment and larger patient populations will be required.


Subject(s)
Catheterization, Central Venous/adverse effects , Polytetrafluoroethylene , Renal Dialysis , Stents , Vascular Diseases/surgery , Aged , Aged, 80 and over , Arteriovenous Shunt, Surgical , Blood Vessel Prosthesis , Constriction, Pathologic , Female , Humans , Male , Middle Aged , Vascular Diseases/etiology , Vascular Patency , Veins/pathology
10.
J Vasc Access ; 11(4): 303-11, 2010.
Article in English | MEDLINE | ID: mdl-20658454

ABSTRACT

PURPOSE: To compare the immediate results of ultrahigh-pressure (UHP) balloons vs. peripheral cutting balloons (PCB) for the treatment of stenoses associated with autogenous fistulas using intra-access blood flow measurements. MATERIALS AND METHODS: This prospective randomized study consisted of 22 hemodialysis (HD) patients with autogenous fistulas who had decreased intra-access blood flow (<500 mL/min). All patients underwent a fistulogram and intraprocedural blood flow measurements. Patients were randomized once into two groups; one group undergoing UHP angioplasty and the second group undergoing PCB angioplasty. Randomization occurred once after the diagnostic fistulogram and each patient in each arm only underwent percutaneous transluminal angioplasty with either UHP or PCB. The study cohort consisted of 12 patients in the UHP group and 10 patients in the PCB group. Data collected included fistula anatomy, degree of stenosis, length of stenosis, balloon specifications and residual stenosis. RESULTS: The 22 study patients underwent 35 angioplasty procedures; 23 in the UHP group (12 patients) and 12 in the PCB group (10 patients). The technical success rate was 91%. The pre-intervention mean blood flow was 288 mL/min in the UHP group and 391 mL/min in the PCB group. The post-intervention mean blood flow was 613 mL/min in the UHP group and 606 mL/min in the PCB group. The mean increase in blood flow was 325.8 mL/min in the UHP group and 213 mL/min in the PCB group. This represents a relative mean increase in blood flow of 253% in the UHP group and 85% in the PCB group. An unpaired t-test showed there was no significant difference between the groups with respect to pre-flow, post-flow, and mean and relative mean increase in flow. There were two failures; one in the UHP group and one in the PCB group. There was one minor complication (2.8%) but no major complications. CONCLUSIONS: In this small group of HD patients with autogenous fistulas our comparison of UHP to the PCB demonstrated that the immediate results, as determined by measurement of intra-access blood flow, were equivalent. Further long-term follow-up will be required to determine the longevity of these results.


Subject(s)
Angioplasty/instrumentation , Arteriovenous Shunt, Surgical/adverse effects , Graft Occlusion, Vascular/therapy , Aged , Aged, 80 and over , Angioplasty/adverse effects , Angioplasty/methods , Blood Flow Velocity , Constriction, Pathologic , Equipment Design , Female , Graft Occlusion, Vascular/diagnostic imaging , Graft Occlusion, Vascular/etiology , Graft Occlusion, Vascular/physiopathology , Humans , Male , Middle Aged , Ontario , Pressure , Prospective Studies , Radiography , Regional Blood Flow , Time Factors , Treatment Outcome , Vascular Patency
14.
J Vasc Interv Radiol ; 21(7): 963-8, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20418112

ABSTRACT

A common problem in the management of patients who are undergoing hemodialysis is central venous occlusive disease. There has been extensive literature on the treatment of this important and prevalent problem. Treatment options to date include percutaneous balloon angioplasty, bare metal stents, and surgical bypass. Unfortunately, all the available treatment options have poor long-term patency, requiring repeated interventions. More recently, covered stents have been mentioned in the literature for the treatment of central venous stenosis and obstruction. There are very few data to date on this technology, and further randomized controlled trials will be needed to compare the efficacy of percutaneous balloon angioplasty, bare metal stents, and covered stents. It appears that it is of paramount importance to prevent this difficult problem by limiting access to, or intervention in, the central venous system.


Subject(s)
Blood Vessel Prosthesis , Renal Dialysis/adverse effects , Stents , Upper Extremity Deep Vein Thrombosis/etiology , Upper Extremity Deep Vein Thrombosis/prevention & control , Humans
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