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Int J Immunogenet ; 33(5): 371-3, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16984282

ABSTRACT

A novel allele HLA-B*2730 and the haplotype HLA-A*03-B*2730-Cw*02-DRB1*16-DRB5 have been found in a Slovene patient and his mother. The exon 2 sequence is identical to that of HLA-B*2702, and the exon 3 sequence is identical to that of HLA-B*2719. A possible mechanism for the generation of B*2730 is a gene conversion event.


Subject(s)
Glomerulonephritis, IGA/genetics , HLA-B Antigens/genetics , Adult , Alleles , Amino Acid Sequence , Female , Glomerulonephritis, IGA/surgery , HLA-B27 Antigen , Haplotypes , Histocompatibility Testing , Homozygote , Humans , Male , Molecular Sequence Data , Sequence Alignment , Transplantation Immunology , Waiting Lists
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