[Thromboembolic risk factors in kidney transplantation: hemorheologic examination in secondary polycythemia]. / Thromboembolische Risikofaktoren bei Nierentransplantierten--hämorheologische Untersuchungen bei sekundärer Polyglobulie.

Cardiovascular risk factors will increase the lethality of kidney patients being under dialysis treatment and after transplantation. This risk is additionally increased after transplantation by secondary polycythemia. The paper investigates the rheological properties of the blood of 20 patients affected by secondary polycythemia after kidney transplantation, 10 patients without polycythemia after kidney transplantation and 19 test persons. Plasma viscosity, erythrocyte aggregation and whole blood viscosity were determined. As a result, an increase of erythrocyte aggregation without their deformability being changed could be found in patients affected by polycythemia after kidney transplantation. The reduced thrombocyte aggregation identified in these patients can be explained by the influence of therapy.

[Hemorheologic findings in patients with ischemic heart disease]. / Hämorheologische Befunde bei Patienten mit ischämischer Herzkrankheit.

The paper deals with the rheological properties of the blood of 38 male patients affected by ischaemic heart diseases (age: 40-75 years) and 19 healthy test persons of comparable age. The following haemorheological properties were measured. 1. Relative plasma viscosity 2. Erythrocyte aggregation 3. Erythrocyte deformability 4. Thrombocyte aggregation and 5. Whole blood viscosity. For the purpose of representing and assessing the results of measurement obtained a division was made into different groups according to the appearances of ischaemic heart disease (chronic ischaemic heart disease, unstable angina pectoris, acute heart infarct) and risk factors (smoking, diabetes mellitus, blood high pressure and hyperlipidaemia). The methods 1-3 proved to be especially suitable for representing gradual differences in the examined rheological parameters. The results obtained are discussed and evaluated.

[Thromboembolism risk factors in kidney transplant patients with secondary erythrocytosis in relation to hemorheologic aspects]. / Untersuchungen zum Problem thromboembolischer Risikofaktoren bei Nierentransplantierten mit sekundärer Polyglobulie unter hämorheologischen Aspekten.

In patients undergoing dialysis and patients who underwent a transplantation of a kidney cardiovascular risk factors increase the lethality to 50%. A secondary polyglobulia (Pg) after transplantation enhances the risks of thromboembolism. In 180 patients who underwent a transplantation we saw in 11% a polyglobulia with 50% of thromboembolic complications. For the study of the secondary polyglobulia and other risk factors haemorheologic investigations were carried out on 20 patients who underwent a transplantation with Pg, 10 patients who underwent a transplantation without Pg and 19 healthy test persons. In patients with secondary polyglobulia we found a slightly increased plasma viscosity and an increase of the aggregation of the erythrocytes without decrease of their deformability. A decreased deformability of the erythrocytes in patients who underwent a transplantation with Pg and diabetes results in an additional risk, as was casuistically observed on a patient with 2 amputations of the legs and 2 myocardial infarctions. Our findings confirm the correctness of the isovolaemic haemodilution for the avoidance of additional cardiovascular complications in patients who underwent a transplantation of a kidney with polyglobulia.