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4.
Angew Parasitol ; 29(2): 81-4, 1988 Jun.
Article in German | MEDLINE | ID: mdl-3177938

ABSTRACT

Prevention of connatal toxoplasmosis is only possible by early diagnosis and treatment of toxoplasma-primoinfection in pregnancy. The authors describe the diagnostic approach and report on 110 pregnant women with toxoplasma-primoinfection. Treatment consisted in the application of pyrimethamine in combination with a sulfonamide or spiramycine. Side-effects of pyrimethamine are mentioned. The aim is an improvement of diagnosis and therapy.


Subject(s)
Pregnancy Complications, Infectious/drug therapy , Pyrimethamine/therapeutic use , Toxoplasmosis, Congenital/prevention & control , Toxoplasmosis/drug therapy , Animals , Antibodies, Protozoan/analysis , Female , Humans , Pregnancy , Pregnancy Complications, Infectious/diagnosis , Pyrimethamine/adverse effects , Toxoplasma/immunology , Toxoplasmosis/diagnosis
7.
Zentralbl Gynakol ; 110(11): 671-6, 1988.
Article in German | MEDLINE | ID: mdl-3137734

ABSTRACT

The authors describe prevalence, diagnosis and treatment of genital schistosomiasis. Schistosomiasis is one of the most common parasitoses in tropical and subtropical developing countries. Genital schistosomiasis is caused by Schistosoma haematobium. By microscopical examination of abradates, operation material and coni schistosoma eggs could be detected in 29.2 per cent of all cases.


Subject(s)
Developing Countries , Genital Diseases, Female/pathology , Schistosomiasis haematobia/pathology , Animals , Biopsy , Female , Genital Diseases, Female/drug therapy , Genitalia, Female/pathology , Humans , Mozambique , Praziquantel/therapeutic use , Schistosoma haematobium/ultrastructure , Schistosomiasis haematobia/drug therapy
8.
Angew Parasitol ; 28(1): 3-5, 1987 Mar.
Article in German | MEDLINE | ID: mdl-3300435

ABSTRACT

Expanding drug-resistance of P. falciparum strains is one of the main problems of the control and treatment of malignant tropical malaria. The World Health Organisation recommends the in vivo test as well as macro and micro in vitro tests for the epidemiological and clinical diagnosis. The authors describe the methodology of these tests, which helped them to identify the first chloroquine-resistant P. falciparum strains from Moçambique and Angola as well as one fansidar-resistant strain from Angola.


Subject(s)
Antimalarials/pharmacology , Plasmodium falciparum/drug effects , Animals , Chloroquine/pharmacology , Drug Combinations/pharmacology , Drug Resistance , Humans , Pyrimethamine/pharmacology , Reagent Kits, Diagnostic , Sulfadoxine/pharmacology , World Health Organization
10.
Angew Parasitol ; 26(2): 65-9, 1985 May.
Article in German | MEDLINE | ID: mdl-4025909

ABSTRACT

Tactics and strategy of malaria control. Both from the qualitative and quantitative point of view malaria can be regarded as one of the most serious medical problems of developing countries. In spite of decades of endeavours by the endemic countries and the World Health Organization using various tactics and strategies malaria prevalence and incidence could not be decreased essentially in tropical developing countries. The author analyses the reasons for this failure and gives realistic recommendations for lowering malaria morbidity and mortality taking into consideration the socio-economic conditions prevailing in the Third World.


Subject(s)
Malaria/prevention & control , Animals , Anopheles/physiology , Chloroquine/therapeutic use , Developing Countries , Female , Humans , Malaria/drug therapy , Malaria/epidemiology , Mosquito Control , Quinine/therapeutic use , Socioeconomic Factors
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