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Int J Biol Macromol ; 183: 1881-1890, 2021 Jul 31.
Article in English | MEDLINE | ID: mdl-34090850

ABSTRACT

Bioplastics have been an interesting area of research and development in the last few decades. Normal plastics are made out of petroleum products, which is a non-renewable resource. Apart from that, its non-biodegradable nature makes it a serious threat to the environment, and hence a better alternative is needed. Bioplastics are synthesized by microorganisms and are biodegradable; this property makes them a promising alternative to normal plastic. However, the major drawback related to bioplastic is the high cost of its production. Polyhydroxyalkanoate (PHA) is a very popular biopolymer produced by different types of microbes. The review focuses on the different methods of extraction of PHA based on the percentage of purity, recovery, eco-friendly, and cost-effectiveness. There is a wide array of extraction methods reported to date, wherein there is the involvement of different types of solvents (like halogenated, non-halogenated, and green solvents) or mechanical or enzymatic methods. Each extraction process has its advantages and disadvantages. In this study, we have attempted to present a structured comparison of these different methods and highlight the factors that can be addressed for better extraction of PHA thereby making it a feasible alternative to commercial synthetic plastic.


Subject(s)
Polyhydroxyalkanoates/isolation & purification , Solvents/chemistry , Biodegradable Plastics/chemistry , Biosynthetic Pathways , Polyhydroxyalkanoates/biosynthesis
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