ABSTRACT
The incidence of lymphomas (Hodgkin's disease, non-Hodgkin lymphoma), chronic lymphatic leukaemia was compared in four provinces in Lower Silesia. The highest incidence was in the Province of Wroclaw, followed in decreasing order by Legnica, Walbrzych and Jelenia Góra. The mean annual crude index of the incidence of these diseases was in these provinces respectively: Hodgkin's disease: 2.51; 1.94; 2.46; 1.65. Non-Hodgkin lymphoma: 1.72; 1.63; 1.68; 1.66. Chronic lymphocytic leukaemia: 2.10; 1.86; 1.28 and 1.62. The highest increasing trend in this incidence was noted in the province of Legnica and the Province of Wroclaw, and in these provinces the prognosis for future increase was worst. In the Province of Legnica the highest increasing tendency of non-Hodgkin lymphoma was noted. The much higher incidence of these malignancies in Lower Silesia in relation to the whole country suggests that some factors there may increase the susceptibility to this disease. However, in relation to other countries, this incidence is within the range of moderate values.
Subject(s)
Hodgkin Disease/epidemiology , Leukemia, Lymphocytic, Chronic, B-Cell/epidemiology , Lymphoma, Non-Hodgkin/epidemiology , Female , Humans , Male , Poland/epidemiology , Rural Population , Sex Factors , Urban PopulationABSTRACT
The synthetic factor based on determinations of 10 parameters in sera of patients with ovarian carcinoma, was constructed. The factor was found to be useful in evaluation of the effectiveness of the cytotoxic treatment and in indication of the recurrence of the malignancy. Reduction of the number of biochemical markers to five (haptoglobin, seromucoid, lactate dehydrogenase, alkaline phosphatase, aspartate aminotransferase), according to significance of particular markers in the laboratory diagnostics of ovarian cancer did not affect the diagnostic sensitivity of the synthetic factor.
