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1.
Jpn J Compr Rehabil Sci ; 13: 17-25, 2022.
Article in English | MEDLINE | ID: mdl-37859844

ABSTRACT

Oishi K, Nishioka S, Okazaki Y, Hirakawa K, Nakamura M, Ichinose A, Kurihara M. Relationship between oral hygiene and function and activities of daily living at discharge in convalescent patients with stroke. Jpn J Compr Rehabil Sci 2022; 13: 17-25. Objective: This study was designed to examine the relationship between improvement in oral hygiene and function and activities of daily living (ADLs) at discharge in patients admitted to convalescent rehabilitation wards. Methods: Eligible criteria were patients with stroke with a score of 13 or higher (i.e., severe oral problems) on the Revised Oral Assessment Guide (ROAG) at admission. Age, gender, primary diseases, rehabilitation dose, dentist visits and denture status, Eichner classification, eating status at admission and discharge, and body mass index at admission were collected. The patients were classified into two groups: those with ROAG scores of less than 9 points at discharge (good ROAG group) and those with scores of 9 points or more (poor ROAG group), and Functional Independence Measure (FIM) gain and total FIM discharge scores were compared using univariate and multivariate analyses. Results: The good and poor ROAG groups comprised 126 and 366 patients, respectively. The good ROAG group had significantly higher total FIM score, FIM efficiency, and FIM gain at discharge than the poor ROAG group (112 vs. 82; P < 0.001). The ROAG scores at discharge were independently associated with FIM gain (partial regression coefficient = -9.889, 95% confidence interval = -13.499 to -6.279) and total FIM score at discharge. Conclusion: Improvement in oral hygiene and function in convalescent patients with stroke was associated with ADLs at hospital discharge.

2.
Gan To Kagaku Ryoho ; 48(10): 1284-1286, 2021 Oct.
Article in Japanese | MEDLINE | ID: mdl-34657065

ABSTRACT

We experienced a case of kidney metastasis of a gastric tumor. An 81-year-old man underwent distal gastrectomy with D2 lymph node dissection and partial hepatic resection for antral gastric tumor with hepatic infiltration in July 2019. A histological examination showed undifferentiated tubular adenocarcinoma. The final stage was pT4bN1P0H0M0, Stage ⅢB. He rejected the recommended adjuvant chemotherapy. Seven months after surgery, abdominal enhanced CT showed a hypovascular mass, 20 mm in diameter, on the right upper pole of kidney. Eleven months after surgery, CT showed that the mass had enlarged to 35 mm, infiltrated the renal pelvis, and advanced to para-aortic lymph node metastasis. We performed a retroperitoneoscopic partial right nephrectomy and diagnosed kidney metastasis of the gastric tumor. His right flank pain worsened, and radiotherapy(50 Gy)was performed for the mass and para-aortic lymph node metastasis. His right flank pain resolved. Kidney metastasis of the gastric tumor is very rare. Radiotherapy effectively relieves pain.


Subject(s)
Stomach Neoplasms , Aged, 80 and over , Gastrectomy , Humans , Kidney , Lymph Node Excision , Lymph Nodes , Lymphatic Metastasis , Male , Stomach Neoplasms/surgery
3.
Gan To Kagaku Ryoho ; 48(10): 1293-1295, 2021 Oct.
Article in Japanese | MEDLINE | ID: mdl-34657068

ABSTRACT

A 65-year-old woman underwent distal gastrectomy with D2 lymph node dissection for advanced gastric cancer in November 2016. The histopathological diagnosis was pT3N0M0, pStage ⅡA, HER2-negative. In August 2019, transverse colon stenosis due to peritoneal dissemination was detected, and an ileum-transverse colon anastomosis was performed. Postoperatively, she received chemotherapy with S-1 plus oxaliplatin. After 6 courses, CT revealed an increase in ascites and dissemination nodules. We diagnosed her with progressive disease and initiated second-line chemotherapy, a ramucirumab plus nab-paclitaxel regimen. On the 20th day during the 5th course of treatment, she visited our hospital with acute abdominal pain. CT revealed free air, and we diagnosed acute panperitonitis with a gastrointestinal perforation. Emergency surgery was performed, and perforation of the appendix end and mild cloudy ascites were observed. We performed an appendectomy and intraperitoneal drainage. Histopathological examination revealed perforation of the appendix, possibly as an adverse effect of the ramucirumab. It should be noted that angiogenesis inhibitors may cause the fatal adverse effect of gastrointestinal perforation.


Subject(s)
Appendix , Diverticulum , Stomach Neoplasms , Aged , Albumins , Antibodies, Monoclonal, Humanized , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Female , Gastrectomy , Humans , Paclitaxel/therapeutic use , Stomach Neoplasms/drug therapy , Stomach Neoplasms/surgery , Ramucirumab
4.
Gan To Kagaku Ryoho ; 48(10): 1296-1298, 2021 Oct.
Article in Japanese | MEDLINE | ID: mdl-34657069

ABSTRACT

Chylothorax after esophagectomy is a relatively rare complication that can be difficult to manage. Here, we report a case of refractory chylothorax after surgery for esophageal cancer treated with lymphatic duct lipiodol imaging by inguinal lymph node puncture to confirm patency of the thoracic duct and thoracic duct ligation. A 71-year-old female with esophageal cancer(cT3N0M0)underwent video-assisted thoracoscopic esophagectomy with 2-field lymph node dissection, intrathoracic gastric tube reconstruction, and an enterostomy. A chylothorax appeared when we started enteral nutrition on the day after surgery. She became markedly dehydrated due to over 2,000 mL/day of drainage from the chest drain, and we managed her general condition in the ICU. We started octreotide acetate on postoperative day(POD)6 and etilefrine on POD 8, but neither was effective. Lymphatic duct lipiodol imaging by bilateral inguinal lymph node puncture was performed, and we confirmed leakage from the main thoracic duct. On POD 11, a thoracic duct ligation performed via a thoracotomy revealed that the volume of the chylothorax was remarkably decreased. The chest tube was removed on re-POD 12.


Subject(s)
Chylothorax , Esophageal Neoplasms , Aged , Chylothorax/diagnostic imaging , Chylothorax/etiology , Chylothorax/surgery , Esophageal Neoplasms/surgery , Esophagectomy/adverse effects , Female , Humans , Lymphography , Postoperative Complications/surgery , Thoracic Duct/diagnostic imaging , Thoracic Duct/surgery
5.
Vaccine ; 38(21): 3752-3758, 2020 05 06.
Article in English | MEDLINE | ID: mdl-32265047

ABSTRACT

BACKGROUND: The carriage prevalence of pneumococcus among community-dwelling older adults is not fully understood, especially in superaged societies. Our purpose was to elucidate the carriage prevalence of pneumococcus in the upper respiratory tract among Japanese community-dwelling adults aged ≥65 years. METHODS: We conducted a cross-sectional study of generally healthy community-dwelling adults aged ≥65 years in Nagasaki city, Japan. Demographic and clinical data and nasopharyngeal, oropharyngeal and saliva samples were collected from February 21st, 2018, to December 17th, 2018. The specimens were tested by culture and molecular methods. RESULTS: Among a total of 504 enrolled participants, none were positive for pneumococcus by culture, and 22 were positive by PCR. The overall carriage prevalence was 4.4% (95% CI: 2.8-6.5%). The prevalence was highest in saliva samples, followed by oropharyngeal and nasopharyngeal samples. No demographic characteristics were associated with carriage prevalence, including age (4.7% among participants aged 65-74 years and 4.1% among those 75 years and older). Among the pneumococcal-positive participants, 18.2% were PCV13-covered serotypes. CONCLUSIONS: Our data suggest a low carriage prevalence of S. pneumoniae among community-dwelling older people in Japan.


Subject(s)
Pneumococcal Infections , Streptococcus pneumoniae , Aged , Aged, 80 and over , Carrier State/epidemiology , Cross-Sectional Studies , Humans , Independent Living , Japan/epidemiology , Nasopharynx , Pneumococcal Infections/epidemiology , Pneumococcal Vaccines , Prevalence , Streptococcus pneumoniae/isolation & purification
6.
Nutr Diet ; 77(4): 456-466, 2020 09.
Article in English | MEDLINE | ID: mdl-31499583

ABSTRACT

AIM: To clarify the correlation between malnutrition, muscle mass and oral status, and swallowing function recovery in stroke patients receiving enteral nutrition. METHODS: Patients with stroke and dysphagia receiving any amount of enteral nutrition in rehabilitation wards from 2012 to 2016 were eligible for inclusion in this retrospective study. On admission, body composition by bioimpedance analysis, malnutrition confirmed by the European Society for Clinical Nutrition and Metabolism criteria, oral status, functional independence measure and demographic data were collected. Characteristics were compared between "oral intake alone" and "artificial nutrition" groups based on the discharge status. Kaplan-Meier methods and the Cox proportional hazards model were used to determine explanatory factors for the probability of full oral intake. RESULTS: Among 174 patients, 113 were analysed (55 women; median age, 77 years). Overall, 61% and 39% were classified as "oral intake alone" and "artificial nutrition," respectively. Days from onset to admission to rehabilitation wards and motor Functional Independence Measure were higher in the "oral intake alone" group. Kaplan-Meier analysis demonstrated that patients with lower muscle mass exhibited lower probability of full oral intake (P = .009). The Cox proportional hazards model suggested that lower muscle mass (hazard ratio, 0.493; 95% CI, 0.286-0.850) and poor oral hygiene (hazard ratio, 0.573; 95% CI, 0.333-0.987) were independently correlated with "oral intake alone" status. Malnutrition and other oral status are not related to achieving full oral intake. CONCLUSIONS: Skeletal muscle mass and oral hygiene are independently correlated with full oral intake among stroke patients receiving enteral nutrition during the rehabilitation phase.


Subject(s)
Enteral Nutrition , Stroke , Aged , Humans , Muscles , Nutritional Status , Retrospective Studies
7.
J Rehabil Med ; 44(5): 421-8, 2012 May.
Article in English | MEDLINE | ID: mdl-22549650

ABSTRACT

OBJECTIVE: Inter-organizational coordination is important for rehabilitation disaster relief. The 2011 Great East Japan Earthquake and Disaster was unprecedented, being geographically widespread and multifaceted. Faced with the crisis, rehabilitation professionals established the 10 Rehabilitation-Related Organizations of Rehabilitation Support Service (10-RRO). The objectives of this paper are to provide descriptive epidemiology and assess the activities of 10-RRO. DESIGN: Descriptive. METHODS: Epidemiological data on disability were collected, mainly from official sources. Relief activities were reviewed from daily reports, and the preparedness, initial response and functioning of 10-RRO were assessed with a questionnaire directed at 36 executives of individual organizations. RESULTS: The disaster was characterized by a very low ratio of injuries to death of 0.372, and an odds ratio of deaths among disabled persons of 2.32. 10-RRO provided relief activities at 3 shelters. The total number of dispatch days ranged from 107 to 146, and the cumulative number of professionals and evacuees served was 1,202 and 7,300, respectively. Support activities included prevention of immobilization, daily life support, environmental improvement and transition to temporary housing. The questionnaire survey revealed poor preparedness, satisfactory initial response and support activities, and problems of data collection and advocacy. CONCLUSION: The disaster was characterized by minimal trauma and a great need for preventing immobilization. This first collaborative endeavour was successful.


Subject(s)
Decision Making , Disaster Planning , Earthquakes/mortality , Practice Patterns, Physicians'/statistics & numerical data , Relief Work , Tsunamis/statistics & numerical data , Confidence Intervals , Earthquakes/statistics & numerical data , Epidemiologic Studies , Global Health , Health Care Surveys , Humans , Japan , Odds Ratio , Social Support , Treatment Outcome
8.
Nihon Rinsho ; 69(4): 653-7, 2011 Apr.
Article in Japanese | MEDLINE | ID: mdl-21591419

ABSTRACT

Resumption of spontaneous circulation (ROSC) after cardiac arrest is an unnatural pathophysiological state. In 2008, ILCOR has proposed "post-cardiac arrest syndrome (PCAS)". Clinicians must focus on treating to reverse the pathophysiological manifestations of PCAS in bed. Immobility, deconditioning, and weakness are common problems in patients with critical illness. Therapeutic strategies have to be identified to give patients after ROSC the best chance for survival with good neurological function. Concerning the beneficial effects of early mobilization after stroke, and the efficacy of a strategy for whole-body rehabilitation in the earliest days of critical illness on functional outcomes, the intervention of early rehabilitation care by an interdisciplinary team seems to contribute to good long-time outcome of post-cardiac arrest patients.


Subject(s)
Heart Arrest/complications , Heart Arrest/rehabilitation , Humans , Syndrome
9.
Neurorehabil Neural Repair ; 25(6): 540-7, 2011.
Article in English | MEDLINE | ID: mdl-21451116

ABSTRACT

BACKGROUND: A new interdisciplinary postacute rehabilitation unit, the Kaifukuki (convalescent) rehabilitation ward (KRW), has been incorporated into the Japanese medical insurance system since 2000. More than 57 000 beds (45 beds per 100 000 population) are currently available nationwide. The maximal coverage for therapy sessions increased from 2 to 3 hours per day, 7 days a week, in 2006. OBJECTIVE: To investigate how changes in policy affected rehabilitation outcomes of KRWs in a retrospective cohort study of 87 917 patients over 10 years. RESULTS: The mean (standard deviation) age of the patients was 73.0 (13.8) years, and 55.4% were women. Diagnoses included stroke (47.9%); orthopedic diseases, including hip fracture (35.2%); and traumatic brain and spinal cord injury (5.4 %). Onset-admission interval (OAI) was 31.5 (18.6) days, length of stay was 75.9 (46.1) days, and 69.1% were discharged home. Daily therapy time was 79.4 (34.5) minutes. Admission/discharge scores of the Barthel Index and the Functional Independence Measure were 49.3 (31.0)/70.4 (31.9) and 75.3 (31.2)/91.7 (31.8), respectively. Year-by-year comparison revealed that older age, greater initial disability, and shorter OAI were coupled with a higher dose of rehabilitative interventions and a higher rate of home discharge. Longitudinal data from a cohort of hospitals implied a small but significant dose-dependent effect of hours of therapy on rehabilitation outcome after stroke. CONCLUSIONS: Although the organization of KRWs is in flux as the system of hospitals grows, results over the past 8 years suggest that changes in national insurance policies are affecting the quantity and organization of rehabilitation interventions and improvement in patient outcomes.


Subject(s)
Fractures, Bone/rehabilitation , National Health Programs/trends , Nervous System Diseases/rehabilitation , Outcome Assessment, Health Care/methods , Rehabilitation Centers/trends , Aged , Aged, 80 and over , Cohort Studies , Female , Fractures, Bone/epidemiology , Humans , Japan/epidemiology , Longitudinal Studies , Male , Middle Aged , National Health Programs/legislation & jurisprudence , Nervous System Diseases/epidemiology , Rehabilitation Centers/economics , Retrospective Studies
10.
Brain Nerve ; 62(1): 61-71, 2010 Jan.
Article in Japanese | MEDLINE | ID: mdl-20112793

ABSTRACT

According to the data-bank on the patients with acute illness transferred to the emergency hospitals in Nagasaki city and surrounding towns (population: approximately 550,000, 18-22% of the patients were aged 65 years and more), the number of stroke patients per year has been the highest among those patients each year from 1998 to 2007. And over 50% of these stroke patients were 70 years or more. These results suggest that care of elderly patients who have had stroke is a main community-wide concern in emergency medicine. Further, it is well known that older patients who suffer an acute illness and are consequently hospitalized often become physically dependent; this greatly influences to prognosis and the quality of life. In addition, older patients are probably undernourished, and their immune system tends toward functional decline. Therefore, to maximize the effectiveness of stroke care and to improve its outcome in terms of functional effectiveness, it is critical that hospital management of acute stroke patients focuses not only on stroke-specific medical care, but also on the nutritional interventions and rehabilitation offered by a multidisciplinary team. And after acute medical treatment, stabilization, nutrition interventions, and early rehabilitation, patients with disability could be transferred to kaifukuki- rehabilitation wards, in where measures to overcome their disabilities (impairments, activity limitations and also participation restrictions) can be taken by a interdisciplinary team, which can provide effective enriched rehabilitation. Eventually, these patients could be discharged and sent either home, or to care houses, community-based long-term rehabilitation center or to hospital-based long-term rehabilitation center.


Subject(s)
Community Health Services , Comprehensive Health Care , Emergency Medical Services , Neurology , Patient Care Team , Stroke Rehabilitation , Aged , Community Networks , Humans , Interdisciplinary Communication , Japan/epidemiology , Nutrition Therapy , Patient Care Planning , Rehabilitation Centers , Stroke/diagnosis , Stroke/epidemiology , Stroke/therapy
12.
J Periodontal Res ; 38(1): 28-35, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12558934

ABSTRACT

To prevent the onset or progression of periodontitis, we must understand when periodontal pathogens are first harbored and how they develop the biofilm that causes periodontal disease. The purpose of this study was to determine the relationship between clinical status and selected periodontal pathogens in subgingival plaque in school children. This study was conducted with 95 school children, 8-11 years old. The presence and distribution of eight selected periodontal pathogens sampled from the maxillary right first molar were determined by an indirect immunofluorescent technique and compared with clinical parameters. Of the 95 sites sampled, only one site had all eight pathogens and five sites did not have any of the eight pathogens. The mean number of positive pathogens per site was 3.5 +/- 1.8 and mean percentage of positive pathogens was 3.82 +/- 4.22%. The number and total percentage of positive pathogens were strongly correlated with the Plaque Index (PI). In addition, the number of positive pathogens was correlated to the presence of subgingival calculus. The most frequently found pathogens were Campylobacter rectus (84.2%) and Eikenella corrodens (83.2%), and the least, Actinobacillus actinomycetemcomitans serotype c (7.4%). Of the eight pathogens, the frequency and distribution of Porphyromonas gingivalis were significantly correlated with PI and the presence of calculus. In addition, seven sites with both P. gingivalis and Bacteroides forsythus showed a correlation with gingival inflammation. In conclusion, the presence of P. gingivalis or P. gingivalis and B. forsythus may be a risk marker to be sought in screening for the onset of periodontal disease.


Subject(s)
Dental Plaque/microbiology , Gram-Negative Bacteria/classification , Molar/microbiology , Periodontitis/microbiology , Aggregatibacter actinomycetemcomitans/classification , Aggregatibacter actinomycetemcomitans/isolation & purification , Analysis of Variance , Bacteroides/classification , Bacteroides/isolation & purification , Biomarkers , Campylobacter/isolation & purification , Chi-Square Distribution , Child , Colony Count, Microbial , Dental Calculus/microbiology , Dental Plaque Index , Eikenella corrodens/isolation & purification , Female , Fluorescent Antibody Technique, Indirect , Gram-Negative Bacteria/isolation & purification , Humans , Japan , Male , Porphyromonas gingivalis/isolation & purification , Risk Factors , Serotyping , Statistics, Nonparametric
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