[Echocardiographic studies in patients with arterial hypertension and above-normal body weight (preliminary report)]. / Ekhokardiografski prouchvaniia pri bolni s arterialna khipertoniia i nadnormena telesna masa (predvaritelno suobshtenie).

24 echocardiographic parameters were studied in 94 patients with arterial hypertension I and II stage, 25 of the patients were with normal body mass and 65 patients were obese (above normal body mass). Simultaneous M-type and two-dimensional echocardiographic recordings were taken. In the non-obese hypertensive patients the left ventricular hypertrophy was of the concentric type while in the obese hypertensive patients it was of the eccentric type. The correlative analysis between the changes of the echocardiographic parameters and the degree of obesity revealed an exceptionally great correlation with the diastolic and systolic dimensions and the volumes of the left ventricle, the left ventricular muscular mass and its index. The ratio between the left ventricular muscular mass and the left ventricular diastolic volume does not change significantly with the increase of the body mass and could be used for differentiation of the cardiac dilatation which is not due to the increased body mass.

[Benign and malignant hemopathies in elderly patients]. / Dobrokachestvenni i zlokachestvenni khemopatii pri stari khora.

108 patient over 75 years of age, treated in an internal diseases ward during a five-year period, were studied. 62 of them were with benign blood diseases, the women prevailing. The malignant hemopathies were found more frequently in men than in women, the ratio being 2.83:1. 35 of the patients (76%) were with non-Hodgkin's lymphoma and 10.8% of the patients were with Hodgkin's lymphoma. Only single patients suffered from chronic myeloid leukemia, myelofibrosis and blastic leukemia. The survival of the patients with benign hemopathies was shortened considerably because of the polymorbidity in elderly people. The survival of the elderly patients with malignant hemopathies did not differ from that of the patients from the other age groups.

[Epidemiologic studies of the prevalence of arterial hypertension among industrial workers in Stara Zagora]. / Epidemiologichni prouchvaniia vurkhu razprostranenieto na arterialnata khipertoniia pri promishleni rabotnitsi v Stara Zagora.

An epidemiologic study was carried out in June 1986 among 1702 industrial workers from the machine-building and metal-manufacturing industry--956 men and 746 women. 57.9% of the workers were in the 30-39 and 40-49 age groups. Arterial hypertension was found in 16.6% of the examined and borderline hypertension was found in 12.9%. With advancing age the hypertension frequency increases. Men suffer more frequently (18.4%) than women (14.2%). In younger age this difference is statistically significant. A relation was established between hypertension and obesity in both sexes. The characteristics of the hypertension structure and the relation of borderline hypertension with age, sex and body mass are discussed.

[Leukocytosis, the leftward shift of the white blood picture and leukemoid reactions in the internal medicine clinic]. / Levkotsitoza, oleviavane na bialata kruvna kartina i levkemoiodni reaktsii vuv vutreshnata klinika.

The white blood count of 6549 patients with various internal diseases of respiratory, cardiovascular, gastrointestinal, excretory and endocrine systems was studied as well as in neoplasms, collagenosis, etc. with the exception of malignant hemopathies. Leukocytosis was established in 21.8% of them. In almost half of the cases, leukocytosis is low, in 44.6% it ranges from 12-20 X 10(9)/l and in 10.2%--it is high--from 20 to 40 X 10(9)/l. Immature cells in the peripheral blood were established corresponding to stab neutrophils over 0.06-0.10, metamyelocytes, myelocytes reaching myeloblasts in the cases with leukemoid reactions. The leukemoid reactions have, with no exceptions, been of myeloid type and developed in various diseases.

[Malignant hemopathies combined with latent tuberculosis (a report of 2 cases)]. / Maligneni khemopatii, suchetani sus skrito protichashta tuberkuloza (s opisanie na dva sluchaia).

Two cases of a combination of a malignant blood disease with latent tuberculosis are presented. One of the patients was with acute leukemia and the other one was with non-Hodgkin's malignant lymphoma (Lymphosarcoma). The blood disease dominated the clinical picture and determined the severity of the course and the lethal outcome. The post mortem examination revealed hepatosplenic form of miliary tuberculosis in both patients. In one of the patients caseous tuberculosis of the bronchopulmonary, peribronchial and periportal lymph nodes was found, too. The tuberculous process had a latent course without characteristic manifestations but it also led to worsening of the patients' condition.

[Population studies of hypertension in 2 populated areas]. / Populatsionni prouchvaniia na khipertonichnata bolest v dve naseleni mesta.

A population-genetic study on the population of the mountainous villages, in the Rhodopes, was carried out, aiming at the elucidation of the incidence of hypertonic disease (HD), depending on the effect of hereditary factors and risk environmental factors. The values of systolic and diastolic arterial pressure among the population from both villages are distributed in Gauss--Laplacian curves, as a result from the effect of multiple poligens. In one of the villages, the mode of life of the population is considerably close to that of a modern town, hence the risk environmental factors, originated by technization and urbanization, have a stronger effect and as a consequence HD incidence observed is higher--10.05 per cent, whereas in the other village--in the absence of those factors--its incidence is 7.18 per cent. The same are the reasons, in the first village, that affect the females more often than the males (p less than 0.001) and a tendency is obvious for a considerable shift of the disease to an earlier age. In both villages a very low percentage of patients with HD were found that were insensitive to the bitter taste of phenylthiocarbamide.