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Bull Exp Biol Med ; 169(6): 734-737, 2020 Oct.
Article in English | MEDLINE | ID: mdl-33098504

ABSTRACT

The study substantiated the possibility of using peat humic acids for improving endurance during extreme physical exertion. The mature outbred Wistar rats weighing 200-250 g (n=40) were subjected to forced swim test until complete exhaustion. The humic acids (1%) were administered intragastrically (0.5 ml/100 g body weight) 30 min prior to the test. Chronic administration of peat humic acids for 5 days increased physical capacity and endurance of rats in exhaustive forced swim test without the changes in serum lactate and corticosterone.


Subject(s)
Biological Factors/pharmacology , Humic Substances/analysis , Physical Conditioning, Animal/physiology , Physical Endurance/drug effects , Physical Exertion/drug effects , Soil/chemistry , Animals , Corticosterone/blood , Gastric Absorption/physiology , Lactic Acid/blood , Male , Physical Endurance/physiology , Rats , Rats, Wistar , Swimming/physiology
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