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1.
Nature ; 477(7366): 570-3, 2011 Sep 29.
Article in English | MEDLINE | ID: mdl-21918514

ABSTRACT

Delta Scuti (δSct) stars are opacity-driven pulsators with masses of 1.5-2.5 M⊙, their pulsations resulting from the varying ionization of helium. In less massive stars such as the Sun, convection transports mass and energy through the outer 30 per cent of the star and excites a rich spectrum of resonant acoustic modes. Based on the solar example, with no firm theoretical basis, models predict that the convective envelope in δSct stars extends only about 1 per cent of the radius, but with sufficient energy to excite solar-like oscillations. This was not observed before the Kepler mission, so the presence of a convective envelope in the models has been questioned. Here we report the detection of solar-like oscillations in the δSct star HD187547, implying that surface convection operates efficiently in stars about twice as massive as the Sun, as the ad hoc models predicted.

2.
AJR Am J Roentgenol ; 145(3): 517-20, 1985 Sep.
Article in English | MEDLINE | ID: mdl-2992255

ABSTRACT

The clinical, radiographic, and pathologic features of 10 patients with documented malignant small-cell tumor of the thoracopulmonary region (Askin tumor) were reviewed. The tumor represents a distinct pathologic entity of neuroectodermal origin. Clinically, it presents as a chest-wall mass with or without pain. Its radiographic appearance is that of a soft-tissue mass with or without pleural or rib involvement, often with metastatic disease--to the skeletal system, bone marrow, thorax, and sympathetic chain. Two patients developed metastases to the adrenal gland and liver, one after autologous bone marrow transplantation. The radiologist should be aware of this entity and its pattern of metastatic spread since metastases are treated aggressively.


Subject(s)
Carcinoma, Small Cell/diagnostic imaging , Thoracic Neoplasms/diagnosis , Adolescent , Adult , Carcinoma, Small Cell/pathology , Child , Female , Humans , Male , Radiography , Thoracic Neoplasms/diagnostic imaging , Thoracic Neoplasms/pathology
3.
J Clin Endocrinol Metab ; 59(6): 1050-3, 1984 Dec.
Article in English | MEDLINE | ID: mdl-6490793

ABSTRACT

Hyperprolactinemia with amenorrhea and galactorrhea generally has a benign clinical course without treatment. Prolonged amenorrhea due to early surgical castration or premature menopause is, however, associated with reduced bone mass and increased risk of fractures. Previous studies in hyperprolactinemic women suggested an association with decreased cortical bone density. To determine whether hyperprolactinemia is associated with reduced trabecular bone mineral, we studied 13 hyperprolactinemic women and matched normal women by quantitative computed tomographic scans of the vertebral bodies. No patient had taken bromocriptine and one patient had previously unsuccessful transsphenoidal surgery. Each patient was matched with a normal woman on the basis of race, age +/- 52 weeks, parity, exercise, tobacco use, oral contraceptive (OCP) use, and alcohol use. No subject was currently taking OCPs. Calcium, phosphorus, and protein intakes were estimated from a 3-day diet diary. The mean duration of amenorrhea was 98.9 +/- 79.7 (SD) months. The mean height, weight, serum 25-hydroxyvitamin D (25,OHD), serum 1,25 dihydroxyvitamin D [1,25(OH)2D] and daily intakes of calcium, phosphorus, and protein were not different. The bone mineral content for each patient fell within +/- SD of the mean of the normal subjects. The mean bone mineral content (mg K2HPO4 eq/ml) of the patients was 10% less than in the normal subjects (144.6 +/- 31.4 (SD) vs. 160.1 +/- 26.6, P less than 0.05). The slope of the regression of bone mineral content and age (mg K2HPO4 eq/ml X yr) was similar in patients (-2.4 +/- 1.1) and normal subjects (-2.3 +/- 1.0). We conclude that hyperprolactinemia is associated with reduced bone mineral content, but does not necessarily produce persistent acceleration of the age-related decline in bone density.


Subject(s)
Bone and Bones/metabolism , Minerals/metabolism , Prolactin/blood , Spine/metabolism , Adult , Amenorrhea/blood , Amenorrhea/metabolism , Bone and Bones/diagnostic imaging , Calcium/administration & dosage , Diet , Dietary Proteins/administration & dosage , Female , Humans , Phosphorus/administration & dosage , Spine/diagnostic imaging , Tomography, X-Ray Computed
4.
Int J Radiat Oncol Biol Phys ; 9(10): 1567-70, 1983 Oct.
Article in English | MEDLINE | ID: mdl-6629894

ABSTRACT

In treating breast cancer with excisional biopsy and irradiation, a volume of lung underlying the breast and chest wall receives significant doses of irradiation. This irradiation can produce pleural and pulmonary changes that can be seen on routine chest radiographs. In five such cases, we have examined pre and post-treatment computerized tomograms of the chest and show that these radiographic changes are pleural-based and lie within the high dose radiation volume. Failure to correct radiation treatment plans for the influence of lung density results in an increased dose to lung and pleura that could, in theory, exacerbate pulmonary and pleural radiation effects.


Subject(s)
Breast Neoplasms/radiotherapy , Pleural Diseases/diagnostic imaging , Radiation Injuries/diagnostic imaging , Tomography, X-Ray Computed , Adult , Aged , Breast Neoplasms/complications , Female , Humans , Lung Diseases/diagnostic imaging , Lung Diseases/etiology , Middle Aged , Pleural Diseases/etiology , Radiation Injuries/etiology , Radiography, Thoracic/methods
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