ABSTRACT
INTRODUCTION: Pulmonary nodular amyloidosis (PNA) is a phenomenon that is rarely diagnosed anywhere in the world. METHODS: We report a case of a 63-year-old woman who smoked in whom a chest X-ray examination 5 years after diagnosis and radical treatment of a highly differentiated carcinoma of the corpus uteri showed multiple lung metastasis. To elucidate these findings by bronchoscopy and thoracoscopy we took a specimen from the right pleura and from one of the suspicious nodules, which were up to 3 cm in diameter; we also obtained some of the bronchial secretion. RESULTS: The nodules were histopathologically diagnosed as PNA. CONCLUSION: Even if it is rare, PNA also belongs in the differential diagnosis of metastatic cancers. For us evidence of Pseudomonas fluorescens in the sputum is a reason for discussing a chronic, clinical unobtrusive local inflammation with hyperactivity of the B-cells as the hypothetical etiology of the amyloidomas.
Subject(s)
Amyloidosis/diagnosis , Lung Diseases/diagnosis , Lung Neoplasms/diagnosis , Lung Neoplasms/secondary , Amyloidosis/diagnostic imaging , Amyloidosis/pathology , Biopsy , Carcinoma, Endometrioid/surgery , Diagnosis, Differential , Female , Humans , Lung/pathology , Lung Diseases/diagnostic imaging , Lung Diseases/pathology , Lung Neoplasms/diagnostic imaging , Middle Aged , Radiography, Thoracic , Thoracoscopy , Tomography, X-Ray Computed , Uterine Neoplasms/surgeryABSTRACT
We report the case of a 54-year-old woman with no history of atopic diseases or drug allergies who developed a generalized anaphylactic reaction with urticaria and angioedema a few hours after tooth extraction. The skin scratch and RAST tests demonstrated IgE-mediated hypersensitivity to the product Hémofibrine, a hemostatic sponge made of bovine fibrin. Of all RAST controls, only one serum with known positivity to bovine serum albumin (BSA) showed a low degree of positivity to Hémofibrine. Bovine fibrin should be added to the list of medical products that can elicit allergic reactions following dental treatment.