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3.
Antibiotiki ; (9): 843-6, 1975 Sep.
Article in Russian | MEDLINE | ID: mdl-1180539

ABSTRACT

The functional state of the testis due to the effect of antibacterial therapy was studied in 50 patients suffering from chronic inflammatory diseases of the urinary-genital system and treated with neomycin, streptomycin, tetracycline, furadonin and furagin. It was shown that the above nitrofurans and neomycin had a negative effect on the testis function lowering the number of the spermatozoa in 1 ml and the whole ejaculate and their mobility. Contrary to it tetracycline therapy had no significant effect on the spermatozoa number, while the use of streptomycin was accompanied by a certain tendency to an increase in their number. The data were to some extent in certain accordance with the results of the experimental studies.


Subject(s)
Anti-Bacterial Agents/adverse effects , Hydantoins/adverse effects , Nitrofurans/adverse effects , Nitrofurantoin/adverse effects , Testis/drug effects , Adult , Chronic Disease , Depression, Chemical , Humans , Male , Middle Aged , Neomycin/adverse effects , Prostatitis/drug therapy , Sperm Motility/drug effects , Spermatogenesis/drug effects , Spermatozoa/drug effects , Streptomycin/adverse effects , Tetracycline/adverse effects , Time Factors , Urethritis/drug therapy
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