ABSTRACT
A retrospective survey of young servicemen presenting with transitional cell carcinoma of the bladder aged 40 years or below is presented, 19 such patients having been identified over a 20-year period. The results were compared with those of other similar series. The tumour behaviour appears to vary with age at presentation, its propensity for multifocal presentation, recurrence, progression to invasion and mortality all rising over the first 4 decades of life. These trends appear to be linked to grade and stage at presentation, and also tend to rise with age rather than altered tumour behaviour. The follow-up of young adults should thus be the same as for older patients presenting with the same grade and stage tumours.
Subject(s)
Carcinoma, Transitional Cell/epidemiology , Military Personnel , Urinary Bladder Neoplasms/epidemiology , Adult , Age Factors , Age of Onset , Carcinoma, Transitional Cell/pathology , England/epidemiology , Humans , Male , Neoplasm Recurrence, Local , Retrospective Studies , Urinary Bladder/pathology , Urinary Bladder Neoplasms/pathologySubject(s)
Circumcision, Male , Cold Temperature , Penile Erection , Postoperative Care/methods , Chlorofluorocarbons, Methane , Ethyl Chloride , Humans , MaleABSTRACT
A controlled study of the effects of wiping skin dry after application of aqueous povidone-iodine was carried out in 24 subjects. There was no significant difference in the reduction from baseline counts of skin flora at 5, 30, 60 and 120 min between wiping the agent off after 30 s of application and leaving it to dry. It would appear that wiping skin dry that has been prepared for operation with this solution in order to allow application of adhesive drapes is a bacteriologically safe practice.
Subject(s)
Povidone-Iodine/administration & dosage , Preoperative Care/methods , Skin/microbiology , Administration, Topical , Adolescent , Adult , Aged , Aged, 80 and over , Colony Count, Microbial , Disinfection , Female , Humans , Male , Middle Aged , Time FactorsABSTRACT
An animal model was used to determine the potential for causing wound infections of bacteria isolated from marine recreational beaches in Hong Kong. Water samples were characterized physically, chemically and bacteriologically and used to inoculate artificially-induced wounds in rats. Morbidity and mortality correlated significantly (P < 0.01) with MacConkey plate counts and faecal coliform counts (membrane filtration) and inversely with salinity of the water. The majority of deaths were due to infection caused by marine and estuarine bacteria rather then enteric organisms. A total of 318 bacterial strains was isolated from the wounds and blood of animals inoculated with seawater, of which 242 were marine/estuarine (predominantly Vibrio spp., Aeromonas hydrophila and Pseudomonas putrefaciens) and 40 were enterobacteria. The virulence of the animal strains were comparable with those from clinical sources.
Subject(s)
Bacterial Infections/microbiology , Bathing Beaches , Water Microbiology , Wound Infection/microbiology , Animals , Bacteria/isolation & purification , Bacteria/pathogenicity , Bacterial Infections/mortality , Disease Models, Animal , Hong Kong , Male , Rats , Rats, Sprague-Dawley , Seawater/adverse effects , Virulence , Water Pollution , Wound Infection/mortalityABSTRACT
Seven cases of injury from an outboard motor propeller are reported and the literature reviewed. The injuries are uncommon, but appear to have a high rate of morbidity and mortality. Wound contamination at the time of injury is discussed. These wounds are best treated by excision of dead tissue and delayed primary suture plus antibiotics, which should include cover against the Vibrionaceae.
