[Microbial flora in wounds and their sensitivity to antibiotics in chronic kidney failure patients before and after kidney transplant]. / Izuchenie ranevoi mikrobnoi flory i ee chuvstvitel' nosti k antibiotikam u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu do is posle transplantatsii pochki.

In vitro bacteriological investigation of various pathological materials revealed the main etiological profile of purulent complications in patients with chronic renal insufficiency before and after allotransplantation of the kidney. A statistically significant magnitude of the frequency of detecting identified pathogens in patients wit renal insufficiency is presented. Phage typing of pathogenic staphylococci isolated from patients with chronic renal insufficiency and from patients after kidney allotransplantation revealed no correlation in belonging of the isolates to a definite phage group in such patients. The effect of semi-synthetic penicillins on gram-positive and gram-negative organisms is estimated. The efficacy of the antibiotic effect on various species of pathogenic micro-organisms isolated from patients with renal affections is shown on the basis of a number of criteria, such as the ranges of the microbial sensitivity, the antibiotic MIC with respect to the majority of the strains, the character of the drug effect.

[Effectiveness of antibiotic therapy in pyelonephritis after kidney transplantation]. / Effektivnost' antibiotikoterapii pri pielonefritakh u bol'nykh posle transplantatsii pochki.

Determination of bacteriuria, leucocyturia, active leucocytes and Sternheimer-Malbin's cells in patients with transplanted kidneys during the postoperative period provided identification of pyelonephritis in the transplanted kidney. E. coli, Proteus, Staphylococcus, P. aeruginosa and microbial associations were the main causative agents of pyelonephritis in such patients. The majority of the causative agents were polyresistant to antibiotics. Investigation of the microbial sensitivity to antibiotics and determination of their levels in the patients promote development of rational schemes for the treatment of pyelonephritis. Early identification of pyelonephritis of the transplanted kidney and its timely treatment with antibiotics allow avoiding destruction of the transplanted organ and promote its normal functioning.

[Study of total magnesium concentration in the blood of patients after surgery with extracorporeal circulation]. / Izmenenie kontsentratsii obshchego magniia v krovi bol'nykh, perenesshikh operatsiiu s iskusstvennym krovoobrashcheniem

In 30 patients with acquired and 14 with congenital heart diseases operated on under extracorporeal circulation a significant decrease in the blood Mg level was noted, its amount never returning to the preoperative one within the first week. Therapy with Mg salts helped to prevent these disorders and to maintain the plasma and erythrocytes Mg levels within the normal limits throughout the whole period of therapy.