Subject(s)
Adenoma, Sweat Gland/pathology , Adenoma, Sweat Gland/therapy , Adult , Humans , Male , Sex FactorsSubject(s)
Facial Neoplasms/pathology , Skin Neoplasms/pathology , Aged , Diagnosis, Differential , Humans , MaleABSTRACT
Neutrophilic eccrine hidradenitis is an entity previously reported to occur in association with malignancy and chemotherapy. We report a case of clinical and histopathologic findings characteristic of neutrophilic eccrine hidradenitis occurring without apparent underlying disease. In addition, the only medication this patient was taking was acetaminophen. Neutrophilic eccrine hidradenitis appears to represent a reaction pattern without specificity for underlying disease or inciting agent.
Subject(s)
Eccrine Glands/pathology , Neutrophils/pathology , Sweat Gland Diseases/pathology , Sweat Glands/pathology , Acetaminophen/adverse effects , Epithelium/pathology , Humans , Inflammation/pathology , Male , Middle Aged , Necrosis/pathologyABSTRACT
Letterer-Siwe disease, a proliferative disorder of Langerhans' cells, usually affects children during the first year of life. A 67-year-old woman is described here whose initial manifestation was a characteristic skin eruption. The clinical, pathologic, and ultrastructural features of Letterer-Siwe disease are reviewed and their role in diagnosis discussed.
Subject(s)
Histiocytosis, Langerhans-Cell/pathology , Aged , Female , Humans , Skin/pathologyABSTRACT
The successful employment of a carbon dioxide (CO2) laser in the eradication of localized chromomycosis is described. A review of alternative medical and surgical modalities used in treating this disorder is presented. The potential benefits of CO2 laser vs. cold steel surgery are discussed.
Subject(s)
Chromoblastomycosis/surgery , Laser Therapy , Aged , Chromoblastomycosis/pathology , Evaluation Studies as Topic , Female , HumansSubject(s)
Cryptococcosis/diagnosis , Homosexuality , Skin Ulcer/diagnosis , Adult , Cryptococcosis/pathology , Forehead , Humans , Male , Skin/pathology , Skin Ulcer/pathologyABSTRACT
An in vitro system developed for studying lymphocyte binding to high endothelial venules (HEV) of lymph nodes was used to determine if there are similar binding sites in other organs of the rat. Thoracic duct lymphocytes (TDL) adhered selectively and uniformly to white matter when overlaid onto glutaraldehyde-fixed tissue sections of cerebellum and cerebrum. The pattern of TDL adherence to cerebellar sections showed that binding to nonmyelinated areas was negligible. Comparison of TDL-white matter to TDL-HEV binding demonstrated that the density of adherence to each site was quantitatively similar. In contrast, lymphocytes exhibited little tendency to bind to tissue sections of liver, spleen, heart, thymus, and salivary glands. TDL adherence to cerebellar white matter occurred rapidly, was cell dose dependent and optimal at 7 degrees C. White matter binding was also a property of spleen lymphocytes but the thymus was deficient in cells with this capability. The affinity of TDL and spleen lymphocytes for myelinated areas of the brain suggests the presence of myelin binding receptors on these cells.
