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2.
Can J Anaesth ; 41(7): 613-20, 1994 Jul.
Article in English | MEDLINE | ID: mdl-8087910

ABSTRACT

To determine the incidences of side effects and complications associated with the use of epidural analgesia for infants and children at the Alberta Children's Hospital, we reviewed our experience over a two-year period. A database was established for recording management, side effects and complications of each epidural, and this is a retrospective review of that database. Problems were identified as complications if there was a need for medical intervention related to the patient complaint, and if the intervention was documented in the patient record. Continuous epidural analgesia with bupivacaine 0.125% or bupivacaine 0.1% with epinephrine was used for managing postoperative pain in 190 children with mean age 5.6 yr (range 1 mo to 18 yr) and the mean weight 22 kg (range 4-88 kg). Mean duration of the epidural infusions was 4.7 days (range 1-16 d). In 127 patients, 203 complications were recorded. Complications, in order of frequency, were nausea and vomiting (23% of patients), motor blockade (15.8% of patients), over-sedation (6.3% of patients), and pruritus (5.2% of patients). Four patients had complications which were potentially related to toxic effects of, or resistance to, bupivacaine, and serum levels of bupivacaine were measured at 3.86, 5.5, 2.1 and 2.34 micrograms.ml(-1). Early discontinuation of the epidural occurred in 41 cases, technical problems with the epidural catheter being the commonest reason (21 cases). Although three potentially serious complications were identified (one catheter site infection, one seizure, one respiratory depression) none was associated with lasting consequences. The majority of complications associated with the use of epidurals were minor and easily remedied.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Analgesia, Epidural/adverse effects , Bupivacaine/adverse effects , Pain, Postoperative/prevention & control , Adolescent , Analgesia , Analgesia, Epidural/instrumentation , Analgesia, Epidural/methods , Bacterial Infections , Bupivacaine/administration & dosage , Bupivacaine/blood , Catheterization/adverse effects , Catheterization/instrumentation , Child , Child, Preschool , Drug Tolerance , Fentanyl/adverse effects , Humans , Infant , Respiration/drug effects , Retrospective Studies , Seizures/chemically induced , Sleep Stages/drug effects , Tachyphylaxis , Time Factors , Ureter/surgery
3.
Can J Anaesth ; 41(6): 523-6, 1994 Jun.
Article in English | MEDLINE | ID: mdl-8069995

ABSTRACT

A 13-yr-old boy was scheduled for emergency appendicectomy because of abdominal pain. His preoperative medical history was complicated by a recent hospital admission for management of asthma. He had presented to hospital seven days earlier because of dyspnoea, tachypnoea and oxygen desaturation to 77% on room air. Following admission, he required intensive nonventilatory management of his asthma, including intravenous salbutamol, methylprednisolone, and aminophylline, as well as use of an ipratroprium bromide inhaler and 100% oxygen by mask. He was discharged to the ward, and continued on prednisone (delta-cortisone), beclomethasone inhaler, ipratroprium inhaler, and salbutamol inhaler. During his ICU stay, he complained of nonspecific abdominal pain, interpreted as gastro-oesophageal reflux. After four days, he was discharged to the ward. On his sixth hospital day, he began to experience right-sided lower abdominal pain and right shoulder pain. A surgeon was consulted, and the patient was found to have a very tender right lower quadrant with guarding and rebound pain. He was therefore scheduled for appendicectomy; antibiotic therapy with ampicillin, gentamicin, and metronidazole was initiated.


Subject(s)
Anesthesia, Epidural , Appendectomy , Asthma/drug therapy , Adolescent , Albuterol/administration & dosage , Albuterol/therapeutic use , Appendectomy/methods , Asthma/complications , Asthma/physiopathology , Beclomethasone/administration & dosage , Beclomethasone/therapeutic use , Bupivacaine/administration & dosage , Fentanyl/administration & dosage , Humans , Lidocaine/administration & dosage , Male , Methylprednisolone/administration & dosage , Methylprednisolone/therapeutic use , Morphine/administration & dosage , Pain, Postoperative/prevention & control , Prednisone/administration & dosage , Prednisone/therapeutic use
5.
Can Anaesth Soc J ; 33(4): 505-8, 1986 Jul.
Article in English | MEDLINE | ID: mdl-3742326

ABSTRACT

A case report is presented describing the clinical usefulness of transcutaneous oxygen (PtcO2) monitoring in an infant undergoing tracheoesophageal fistula repair. Its use allowed early and precise recognition of hypoxaemia during periods of surgical manipulation. During periods of hypoxaemia, there were no associated cardiovascular changes or changes in routine monitoring modalities. Clinical use of PtcO2 may detect early hypoxaemia and thus allow for correction before the appearance of changes in vital signs.


Subject(s)
Anesthesia, Endotracheal , Hypoxia/diagnosis , Monitoring, Physiologic/methods , Oxygen/blood , Tracheoesophageal Fistula/surgery , Humans , Intraoperative Complications/diagnosis , Intraoperative Period , Male , Skin/blood supply
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