[The organization of the mass tuberculin diagnosis of children and adolescents]. / Organizatsiia massovoi tuberkulinodiagnostiki u detei i podrostkov.

Expert evaluation of the teamwork on tuberculin diagnosis revealed noticeable defects in this field. There are errors in the reading of the tuberculin tests, cases of overlooked primary infection. Full-value antituberculosis preventive measures are thought more feasible when a phthiopediatrist is included in the team who is responsible for planning the activity of the team, for control of the diagnosis quality, selection of the primary disease cases, chemotherapy prevention, BCG revaccination.

[Rapid method of obtaining enriched fractions of rat brain neuronal and glial cells]. / Metod odnomomentnogo polucheniia obogashchennykh fraktsii neironal'nykh i glial'nykh kletok golovnogo mozga krysy.

Cell suspension of the rat brain was separated into fractions of neuronal and glial cells (FNC, FGC) during 7-10 minutes. The suspension was filtered in the column through a series of filters with 400-600, 200 (FNC), 132 and 100 (FGC) mu pores. The purity of the fractions obtained was analyzed by light microscopy. According to a single cell counting the purity of FNC and FGC contituted 60 and 90%, respectively. The respective figures were 97 and 90% as shown by cell weight comparison. The biochemical and morphological findings indicate a good viability of isolated cells. It has been established that of total rat brain protein (108 mg per 1 g crude tissue), the proteins of nerve cells account for about 30%. The mass ratio of neurons to glial cells is 2.5:1. This fact should be taken into consideration during studies on the functional interactions between neurons and glial cells.

[Changes in the nervous system in acute pneumonia (clinico-pathomorphologic syndrome)]. / Izmeneniia nervnoi sistemy pri ostrykh pnevmoniiakh (kliniko-patomorfologicheskoe issledovanie).

An analysis of clinico-electrophysiological data obtained from 300 patients suffering from focal and croupous pneumonia with nervous system involvement is presented. Clinical syndromes of the nervous system involvement in acute pneumonias are specified. In 7 lethal cases pathomorphological examinations of the brain were carried out. It has been shown that certain complexes of structural and functional non-inflammatory changes in the central nervous system underlie the neurological symptoms. The leading manifestations were: acute progressing dyscirculatory syndrome with impairment of the vascular tone and permeability, dyscirculatory hypoxia and intoxication accompanied with edema of the brain and the pia; dystrophic changes in the neurons, glia and myelin.

[Pathomorphology of the brains of schizophrenic patients treated with psychotropic drugs (concerning drug pathomorphosis)]. / Osobennosti patomorfologii golovnogo mozga bol'nykh shizofreniei, lechennykh psikhotropnymi preparatami (k voprosu o lekarstvennom patomorfoze).

Histological methods demonstrated that the use of psychopharmacological drugs in schizophrenic patients does not remove the characteristic neuron pathology (shrinkage, atrophy, lipofuscin dystrophy, cytolysis), but increases the metabolic processes in the intact nervous cells (an increase in the volume and basophilia in the cytoplasma, an enlargement of nuclei and nucleoli) and the glia activity (an increase in the amount of perineuronal satellites, general glia and the glioneuronal index). It is believed that the treatment does not remove the organic brain defect, but stimulates the metabolic processes in the CNS.