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1.
Int J Artif Organs ; 30(4): 345-51, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17520573

ABSTRACT

The Aachen Total Artificial Heart (ACcor) has been under development at the Helmholtz Institute in Aachen over the last decade. It may serve as a bridge to transplant or as a long-term replacement of the natural heart. Based upon previous in vivo experiments with the ACcor total artificial heart, it was decided to optimize and redesign the pump unit. Smaller dimensions, passive filling and separability into three components were the three main design goals. The new design is called the MiniACcor, which is about 20% smaller than its predecessor, and weighs only 470 grams. Also its external driver/control unit was miniaturized and a new microcontroller was selected. To validate the design, it was extensively tested in laboratory mock loops. The MiniACcor was able to pump between 4.5 and 7 l/min at different pump rates against normal physiological pressures. Several requirements for the future compliance chamber and transcutaneous energy transmission (TET) system were also measured in the same mock loop. Further optimization and validation are being performed in cooperation with the Heart and Diabetes Centre North Rhine-Westphalia.


Subject(s)
Heart, Artificial , Prosthesis Design , Animals , Aorta/surgery , Biomedical Engineering/instrumentation , Cardiac Volume/physiology , Cattle , Heart Atria/surgery , Humans , Miniaturization , Polyurethanes/chemistry , Polyvinyl Chloride/chemistry , Pulmonary Artery/surgery , Stroke Volume/physiology
2.
Int J Artif Organs ; 29(12): 1132-9, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17219353

ABSTRACT

The aim of this study was to validate the flow characteristics of the novel Helmholtz-Institute Aachen Bileaflet (HIA-BL) heart valve prosthesis. The curved leaflets of the HIA-BL valve form a Venturi passage between the leaflets at peak systole. By narrowing the cross section the flow accelerates and the static pressure at the central passage decreases according to the Venturi effect. The low-pressure zone between the leaflets is expected to stabilize the leaflets in fully open position at peak systole. To investigate the Venturi passage, the flow fields of two valve geometries were investigated by CFD (Computational Fluid Dynamics): one geometry exhibits curved leaflets resulting in a Venturi passage; the other geometry features straight leaflets. The flow profiles, pressure distribution and resulting torque of both passages were compared and investigated. Although flow profiles downstream of both valves were similar, the flow passages between the leaflets were different for the investigated leaflet geometries. The straight leaflet passage showed a large boundary layer separation zone near the leaflets and the lowest pressure at the leading edge of the leaflet. The Venturi passage showed a reduction of the boundary layer separation zones and the lowest pressure between the leaflets could be found in the narrowest flow cross section of the Venturi passage. Additionally, the resulting torque showed that the Venturi passage produced an opening momentum. The results demonstrate that the Venturi passage stabilizes the leaflets in open position at peak systole.


Subject(s)
Heart Valve Prosthesis , Hemorheology , Numerical Analysis, Computer-Assisted , Blood Flow Velocity , Blood Pressure , Equipment Failure Analysis , Humans , Models, Cardiovascular , Prosthesis Design , Reproducibility of Results
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