1.
Stud Health Technol Inform
; 52 Pt 1: 372-5, 1998.
Article
in English
| MEDLINE
| ID: mdl-10384481
ABSTRACT
A stochastic simulation program of drug-receptor interaction is presented. The user can select a set of conditions concerning the processes of response release (type of cellular response, drug distribution and metabolism etc.) and the program plots a family of dose-response curves. A comparison between experimental and simulated dose-response curves shows the validity of the model can be used either for testing hypotheses concerning drug-receptor interaction, for experimental design or for estimation of some specific parameters. The program can also be used for educational purposes.