ABSTRACT
The reactivities between saccharides and primary amino compounds were studied by liquid chromatography on an amino-bonded column and by measurement of the reaction rates of aromatic amines with saccharides. The recoveries from the column and the reaction rates were correlated with their physicochemical properties calculated by the CAChe program. The reactivities between amines and saccharides correlated well with their hydrogen bonding energies calculated by molecular mechanics.
Subject(s)
Amines/chemistry , Carbohydrates/chemistry , Chromatography, Liquid , Glycosylation , Hydrogen Bonding , KineticsABSTRACT
A case is reported of sarcoma associated with pregnancy in which the patient underwent a cesarean section with myomectomy and was delivered of a living infant. A pathologic examination indicated sarcoma.
Subject(s)
Leiomyosarcoma/pathology , Pregnancy Complications, Neoplastic , Uterine Neoplasms/pathology , Adult , Cesarean Section , Female , Humans , Hysterectomy , Leiomyosarcoma/surgery , Pregnancy , Uterine Neoplasms/surgeryABSTRACT
We describe a patient 17 weeks pregnant whose complaints were diagnosed as acute abdomen. The patient underwent a total abdominal hysterectomy and uterine rupture was found with, surprisingly, a live fetus. Pathologic examination indicated destructive mole.
Subject(s)
Hydatidiform Mole/complications , Pregnancy Complications, Neoplastic , Uterine Neoplasms/complications , Uterine Rupture/etiology , Adult , Female , Fetus , Humans , Hydatidiform Mole/pathology , Pregnancy , Uterine Neoplasms/pathologyABSTRACT
We succeeded for the first time in extracting and purifying a coagulation fibrinolysis factor in the placenta, that is, a placental plasminogen activator (PPA). Using the enzyme-labeled antibody technique (indirect method), we investigated the localization of PPA, fibrinogen (FBG) and fibronectin (FN) in the placenta. And we tried to elucidate the physiological significance of the above three. The F(ab')2 fragments of their antibodies were produced by pepsin digestion, because there were various Fc receptors in the placenta. The results are summarized as follows: PPA was produced in the trophoblast, and was secreted out of the microvilli. FBG was located in the plasma. But, in the placenta, it was not in the cells and the connective tissue of which chorionic villi was composed. FN was located in the ground substances of connective tissue in the chorionic villi, and was associated with the cell structure. Because PPA, FBG and FN showed the same distribution on the fibrinoid material, it is expected that coagulation fibrinolysis activity proceeds in that fibrinoid material.