Metástasis coroideas y cutáneas como forma de presentación de un adenocarcinoma esofágico / Choroid and cutaneous metastasis as presentation of an esophageal carcinoma

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[Retroperitoneal fibrosis secondary to treatment with L-dopa analogues for Parkinson disease]. / Fibrosis retroperitoneal secundaria a tratamiento con análogos de L-dopa por enfermedad de Parkinson.

OBJECTIVES: The present study describes two patients with retroperitoneal fibrosis following prolonged use of bromocriptine and pergolide for Parkinson's disease. Both patients also presented severe atheromatosis. METHODS: Similar cases reported in the literature are reviewed and the possible relationship between the use of the ergotamine derivate and severe atheromatosis is discussed. RESULTS: Both patients, a 67-year-old male and a 62-year-old female, improved after discontinuing bromocriptine, despite severe damage of renal function. CONCLUSIONS: Retroperitoneal fibrosis may develop in patients with bilateral ureteral obstruction, especially those who have received drugs that have been reported to cause the foregoing condition.