ABSTRACT
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Subject(s)
Humans , Female , Middle Aged , Epilepsy/diagnosis , Intracranial Aneurysm/diagnosis , Diagnosis, DifferentialABSTRACT
INTRODUCTION: Multiple cranial neuropathy is a condition rarely seen in everyday clinical practice. It has many different causes, and in spite of careful clinical investigation many cases remain of unknown aetiology. It is also considered to be an atypical variant, topographically circumscribed, of the Guillan Barr syndrome (GBS). CASE REPORT: A 23 years old man developed a progressive illness over ten days. He complained of diplopia, facial diplegia and a nasal voice. Subsequently, he also developed weakness of the neck and tongue muscles, dysphagia, abolition of reflexes of the left arm and right triceps reflex but without involvement of the respiratory muscles or other limbs. CSF studies showed slightly raised protein with no cells. Neurophysiological studies showed a demyelinating disorder with secondary axonal damage. In spite of further studies, no aetiological agent was found. DISCUSSION AND CONCLUSION: These observations suggested this case is of a topographical variant of GBS. Such cases have also been classified as the Miller Fisher syndrome, pharyngo cervico brachial paralysis, are flexic paraparesia and bilateral lumbar polyradiculopathy. In view of the diversity of the clinical and biological characteristics of the cases reviewed, which may mean different aetiopathogeneses, we consider that a thorough search should be made for the aetiology before these conditions are labelled as atypical variants of GBS.
Subject(s)
Cranial Nerve Diseases/diagnosis , Guillain-Barre Syndrome/diagnosis , Adult , Cranial Nerve Diseases/physiopathology , Guillain-Barre Syndrome/physiopathology , Humans , MaleABSTRACT
8 cases of syringomyelic arthropathy which were detected in 6 patients of 13 afflicted of syringomyelia, are presented. The etiopathogenesis, clinical, radiological, and pathological data are commented on; and an eclectic mechanism which mixed the 3 theories admitted: neurotrophic, neurotraumatic, and neurovascular, is suggested. We found the incidence of arthropathy higher than that described in existing medical literature and concluded that it is necessary to perform wide administer the appropriate therapy.
