ABSTRACT
In the absence of active pulmonary disease, hepatic focal tuberculosis is a rare form of tuberculosis. We present a case of pseudotumoral hepatic tuberculosis in a 44-year-old man; diagnosis is difficult because of its radiological similarity with primary or metastatic hepatic cancer. Percutaneous biopsy with US or CT guidance offers a good diagnostic alternative to laparoscopy. Histology examination revealed a tuberculoid granulomatous lesion. The disease has a good response to tuberculostatic treatment.
Subject(s)
Granuloma, Plasma Cell/diagnosis , Liver Diseases/diagnosis , Tuberculosis, Hepatic/diagnosis , Adult , Antitubercular Agents/therapeutic use , Biopsy, Needle , Diagnosis, Differential , Drug Therapy, Combination , Humans , Liver/diagnostic imaging , Liver/pathology , Male , Radiography , Tuberculosis, Hepatic/drug therapyABSTRACT
We report the case of a male patient with Crohn's disease associated with IgA nephropathy. He was treated surgically for the intestinal disorder and then with corticoids and sulfasalazine. Six years after treatment the patient was asymptomatic. As the intestinal situation improved there was concomitant normalization of urinary sediment, maintaining renal function. The fact that the digestive mucosa is one of the body's major sources of secretory IgA may account for the existence of a common for Crohn's disease and certain forms of IgA nephropathy.
Subject(s)
Crohn Disease/complications , Glomerulonephritis, IGA/complications , Adult , Humans , MaleABSTRACT
Nodular regenerative hyperplasia of the liver was found at liver biopsy and at autopsy in a 61-year-old woman with severe cholestasis. Increased bilirubin levels persisted over a follow-up period of 4 years. Microscopic findings included hyperplastic hepatocytic nodules, interlobular bile duct lesions, fibrous medial and intimal thickening of small arterial branches and portal veins, and recanalization of a thrombus in a major portal branch related to an area of focal nodular hyperplasia of the liver. Bile duct and small vessel changes were prominent in the present case. Their role as contributing factors to the development of nodular regenerative hyperplasia of the liver is discussed.
