ABSTRACT
We analyzed 33 patients with recurring nodular goiter (from a population of 2,500 operated patients). Recurrence occurred 0.7 to 12 years after surgery. T4, T3, TSH, perchlorate and TRH tests were performed in 18. Results were similar to those in 13 operated patients without recurrence. Administration of thyroid hormone did not influence recurrence. Seven patients with recurring goiter were re-operated on; an encapsulated follicular cancer was found in one. Our results suggest that recurrence of nodular goiter after surgery is not prevented by routine use of thyroid hormone.
Subject(s)
Goiter, Nodular/epidemiology , Goiter, Nodular/etiology , Adenoma/epidemiology , Adenoma/etiology , Adenoma/surgery , Chile/epidemiology , Female , Goiter, Nodular/surgery , Humans , Incidence , Male , Recurrence , Reoperation/statistics & numerical data , Thyroid Function Tests/statistics & numerical data , Thyroid Neoplasms/epidemiology , Thyroid Neoplasms/etiology , Thyroid Neoplasms/surgery , Thyroidectomy/statistics & numerical dataABSTRACT
Two patients receiving substitution therapy for Sheehan syndrome became pregnant. No pituitary trophins, except LH responded to stimulation with the hypothalamic hormones TRH and Gn-Rh, or insulin induced hypoglycemia. Computed tomography showed a normal size sella with arachnoid cyst.
Subject(s)
Hypopituitarism/therapy , Pregnancy , Adult , Female , Humans , Hypopituitarism/complications , Hypopituitarism/physiopathology , Hypothalamic Hormones/physiology , Pituitary Function TestsSubject(s)
Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Thyroid Diseases , Thyroid NeoplasmsABSTRACT
El acido triyodotiroacetico no es un anorexigeno sino que un metabolito de las hormonas tiroideas que tiene una accion equivalente al 10% de la que ostentan la tiroxina y la triyodotironina. Se le ha preconizado en el tratamiento de la obesidad debido a su efecto lipolitico periferico residual y pese a que hay consenso entre la gran mayoria de los autores, en estimar que las hormonas tiroideas, sus analogos y sus metabolitos practicamente no tienen ningun lugar en el tratamiento de la obesidad en sus diversas formas fisiopatologicas y clinicas