Machine learning models predict the emergence of depression in Argentinean college students during periods of COVID-19 quarantine.

Introduction: The COVID-19 pandemic has exacerbated mental health challenges, particularly depression among college students. Detecting at-risk students early is crucial but remains challenging, particularly in developing countries. Utilizing data-driven predictive models presents a viable solution to address this pressing need. Aims: 1) To develop and compare machine learning (ML) models for predicting depression in Argentinean students during the pandemic. 2) To assess the performance of classification and regression models using appropriate metrics. 3) To identify key features driving depression prediction. Methods: A longitudinal dataset (N = 1492 college students) captured T1 and T2 measurements during the Argentinean COVID-19 quarantine. ML models, including linear logistic regression classifiers/ridge regression (LogReg/RR), random forest classifiers/regressors, and support vector machines/regressors (SVM/SVR), are employed. Assessed features encompass depression and anxiety scores (at T1), mental disorder/suicidal behavior history, quarantine sub-period information, sex, and age. For classification, models' performance on test data is evaluated using Area Under the Precision-Recall Curve (AUPRC), Area Under the Receiver Operating Characteristic curve, Balanced Accuracy, F1 score, and Brier loss. For regression, R-squared (R2), Mean Absolute Error, and Mean Squared Error are assessed. Univariate analyses are conducted to assess the predictive strength of each individual feature with respect to the target variable. The performance of multi- vs univariate models is compared using the mean AUPRC score for classifiers and the R2 score for regressors. Results: The highest performance is achieved by SVM and LogReg (e.g., AUPRC: 0.76, 95% CI: 0.69, 0.81) and SVR and RR models (e.g., R2 for SVR and RR: 0.56, 95% CI: 0.45, 0.64 and 0.45, 0.63, respectively). Univariate models, particularly LogReg and SVM using depression (AUPRC: 0.72, 95% CI: 0.64, 0.79) or anxiety scores (AUPRC: 0.71, 95% CI: 0.64, 0.78) and RR using depression scores (R2: 0.48, 95% CI: 0.39, 0.57) exhibit performance levels close to those of the multivariate models, which include all features. Discussion: These findings highlight the relevance of pre-existing depression and anxiety conditions in predicting depression during quarantine, underscoring their comorbidity. ML models, particularly SVM/SVR and LogReg/RR, demonstrate potential in the timely detection of at-risk students. However, further studies are needed before clinical implementation.

Alcohol consumption, alcohol expectancies, and drinking contexts in young Argentinean college students before and during the COVID-19 pandemic: a one-year follow-up study.

Background: The COVID-19 pandemic and lockdowns are known to affect alcohol consumption. This study examines drinking expectancies and contexts upon alcohol consumption of Argentinean students.Objectives: To assess within-person changes in alcohol consumption in Argentinean college students (aged 18-24), from August 2019 with a one-year follow-up during the COVID-19 lockdown, considering alcohol expectancies, drinking contexts, and main socio-demographic variables. To validate the stability of these predictors, we discuss the effects on the alcohol consumption across dependent and independent measures.Methods: We assessed one longitudinal (N = 300, 70% female) and one cross-sectional (N = 165, 78% female) sample via online surveys and applied multilevel analysis and regressions, respectively.Results: Alcohol consumption significantly increased during lockdown compared to one-year before (mean: 6.91 and 8.26 alcohol units, correspondingly). In the longitudinal sample, social facilitation (medium effect sizes [ES]: 0.21, 0.22) and parental presence (medium ES: 0.12, 0.21) significantly and stable (through time) predicted increasing effects on consumption. In the cross-sectional sample, stress control (high ES: 0.78) and parental presence (high ES: 0.42) were associated with higher consumption during lockdown.Conclusion: College students increased their alcohol consumption during lockdown, suggesting that restrictive sanitary measures may negatively affect consumption. Literature is not conclusive as both decreases and increases in alcohol consumption in students from developed countries were reported. Before and during COVID-19 lockdown, parental presence is a stable predictor of increased alcohol consumption, though unusual according to the literature. Health policies aimed at modifying the behavior of parents who promote/share alcohol consumption with their offspring may help reduce drinking in college students.

A longitudinal study on depression and anxiety in college students during the first 106-days of the lengthy Argentinean quarantine for the COVID-19 pandemic.

BACKGROUND: The Argentinean quarantine is among the strictest and longest quarantines in the world. To determine if a worsening pattern on mental health would emerge with a prolonged quarantine duration, a longitudinal analysis pertaining to the lengthy mandatory Argentinean quarantine was conducted. AIM: To examine depression and anxiety changes in college students, as a function of quarantine duration, demographic and health-related factors, during successive time cuts of the lengthy mandatory quarantine in Argentina. METHODS: We used a longitudinal design, N = 1492 college students. For the first measurement, successive samplings were carried out across quarantine sub-periods of up to 106-days duration. The follow-up was one month later. RESULTS: Particularly women, young, and having a history of mental disorder and suicidal behavior, were more depressed and anxious under mandatory restrictive quarantine conditions. Repeated measures of both depression and anxiety scores remained constantly high during the more restrictive quarantine sub-periods of up to 13 and 53-days duration, and decreased during the less restrictive quarantine sub-period of up to 106-days duration, but with small effect sizes (0.10-0.08). CONCLUSIONS: Restrictive quarantine has negative effects on mental health outcomes. Partial spontaneous remissions of depression and anxiety symptoms may be expected with further quarantine relaxations.

Levels and predictors of depression, anxiety, and suicidal risk during COVID-19 pandemic in Argentina: the impacts of quarantine extensions on mental health state.

This research is aimed to: analyze differences in mental health state (MHS) indicators (depression, state-anxiety, trait-anxiety, and suicidal risk), during three quarantine sub-periods (starting since the first quarantine extension); assess multiple relationships between each MHS indicator and potentially affecting factors. We used a cross-sectional design with a convenience sample including 1100 participants. Data were collected online. Depression revealed a worsening pattern as quarantine sub-periods went by. Anxiety (both state and trait), just like suicidal risk, partially follow such a pattern, with mean scores increasing from the first to the second/third quarantine extensions, but then maintaining to the fourth extension. Predictors having protective effects on almost all the MHS indicators were: availability of current economic income (except for state-anxiety, without significant effect) and absence of suicide attempt history. Conversely, sex (woman), younger age, and mental disorder history had an increasing risk effect on all the MHS indicators. Overall, our findings indicate that quarantine have negative mental health impacts and that quarantine duration is a relevant aspect to be taken into account when measuring such an impact. More attention needs to be paid to vulnerable groups such as the young, women, and people with history of mental disorder.

A Longitudinal Study on the Changes in Mental Health of Healthcare Workers during the COVID-19 Pandemic.

Objective: This study examines Argentinean health care workers in order to 1) test self-perceived job performance levels and the presence of psychological symptoms compatible with common mental disorders, and 2) examine within-person changes in general discomfort and psychological distress, adjusting for demographic factors, region, and health-related factors during two time points of the COVID-19 pandemic.Method: This longitudinal study comprised 305 healthcare workers who completed a survey at two time points approximately 4 months apart. We used the General Health Questionnaire and the Kessler Psychological Distress Scale to measure mental health outcomes. To address the first aim we calculated differences (Student's t test for paired samples) and correlations (Pearson's r coefficient). To address the second aim we used fixed effects model by means of a multilevel approach, a linear model that considers dependency in the data.Results: Self-perceived job performance deteriorated across time. From the first measurement to the four-month follow-up, more health care workers presented common mental disorders (40% vs 45.57%), depression, and/or anxiety (52.46% vs 62.62%). A meaningful worsening of mental health was observed in healthcare workers who expressed concern about being infected with COVID-19, whether asymptomatic (greater general discomfort and psychological distress) or symptomatic (greater general discomfort). Likewise, there were significant interactions between a history of mental disorder and concern about COVID-19 infection.Conclusions: Among healthcare workers, the uncertainty about the COVID-19 infection may have larger negative mental health impacts than actually being infected.

Changes in Healthcare Workers' Anxiety During Two Time Points of the COVID-19 Pandemic: Evidence From a Longitudinal Study.

Evidence on the within-person changes of healthcare workers' mental health across waves of COVID-19 cases during this pandemic is absent. The aim of this study is to examine the within-person changes of anxiety in Argentinean healthcare workers, adjusting for main demographic factors, region of residence, mental disorder history, and COVID-19 contagion, during the COVID-19 pandemic. A longitudinal web survey (N = 305) was conducted during two time points of the pandemic, one of which was an infection peak. Anxiety significantly increased across time. However, there were significant interaction effects modulating anxiety levels. The largest anxiety increases occurred in healthcare workers who were not sure if they had contracted COVID-19 while symptomatic. Irrespective of the time point, anxiety was the highest in healthcare workers from a region inside the country who were not sure if they had contracted COVID-19, either asymptomatic or symptomatic. An interaction effect between the mental disorder history and the COVID-19 contagion suggested that the anxiety outcomes were mainly due to the concern about the COVID-19 contagion, rather than due to pre-existing mental health vulnerabilities. Regardless of the starting point in anxiety levels, an increasing anxiety outcome may be expected among healthcare workers as the pandemic progresses. The uncertainty regarding COVID-19 contagion is a preventable and modifiable interacting factor to produce the worst anxiety outcomes among healthcare workers.

Suicidal risk and impulsivity-related traits among young Argentinean college students during a quarantine of up to 103-day duration: Longitudinal evidence from the COVID-19 pandemic.

AIM: This study aimed to examine longitudinal changes on suicidal risk levels, adjusting for impulsivity-related traits, quarantine duration, main demographic factors, mental disorder history, and loneliness, in young Argentinean college students with (ideation; attempt) and without suicidal behavior history, during a quarantine of up to 103-day duration of the COVID-19 pandemic. METHODS: A longitudinal design with two-repeated measures was used (N = 1202). Follow-up was a month later from the first measurement. Three groups were analyzed: with suicidal ideation history, with suicide attempt history, and without suicidal behavior history. RESULTS: Percentages of college students with high or moderate suicidal risk were alarming (accumulated: 62.23% first measurement, 57.65% second measurement). Multilevel analysis on the three groups showed that suicidal risk diminished from the first measurement to the follow-up, having mental disorder history predicted higher suicidal risk, and negative urgency had the largest increasing effects on suicidal risk which persisted over time. CONCLUSIONS: Suicidal risk widely affects college students during lengthy quarantines of the COVID-19 pandemic and it should be tracked in those having pre-existing vulnerabilities, but also in those without. Education on managing negative emotions may help decrease suicide risk in college students during the COVID-19 pandemic.

Mental Health Impacts in Argentinean College Students During COVID-19 Quarantine.

Background: We aimed to: (1) analyze differences in both general (in terms of psychological well-being/discomfort, social functioning and coping, and psychological distress) and specific (depression, trait-anxiety, negative alcohol-related consequences, and suicidal risk) mental health state (MHS) in college students, residing in four different Argentinean regions (center, north, south, and the most populated) exposed to different spread-rates of the COVID-19; (2) analyze between-group differences in both general and specific MHS indicators at four quarantine sub-periods (twice prior, and twice following the first quarantine extension). Methods: We used a cross-sectional design with a convenience sample including 2,687 college students. Data was collected online during the Argentinean quarantine. We calculated one-way between-groups ANOVA with Tukey's post hoc test. Results: Regionally, the center and the most populated area differed in psychological well-being/discomfort and negative alcohol-related consequences, but not in the remaining MHS indicators. According to the quarantine sub-periods, there were differences in psychological well-being/discomfort, social functioning and coping, psychological distress, and negative alcohol-related consequences. Negative alcohol-related consequences were the only MHS indicator improving over time. For all of the remaining MHS indicators, we found a similar deterioration pattern in the course of time, with mean scores decreasing from the first to the 2nd week of the quarantine pre-extensions, then increasing toward the 1st week of the quarantine post-extension (with some MHS indicators reaching mean scores worse than the start), and then continued to increase. Conclusion: A worsened mean MHS during quarantine suggests that quarantine and its extensions contribute to negative mental health impacts.

Longitudinal evidence on mental health changes of college students with and without mental disorder background during the Argentina's lengthy mandatory quarantine.

This study examined the changes in the mental health state of college students with and without mental disorder background, during successive time cuts of the Argentina's lengthy mandatory quarantine, while adjusting for quarantine duration, sex, age, suicidal behavior history, loneliness, and region of residence. We used a longitudinal design (N = 1615, 26% with mental disorder history). Successive samplings were performed from three days before quarantine start and across quarantine phases of up to 103-days duration. Follow-up was one month later. Sex (woman) and age (younger) were significant predictors of worse mental health only in college students without mental disorder background. Having any suicidal behavior background significantly predicted worse mental health in college students both with and without mental disorder history. Loneliness and region of residence were not statistically significant. In the between-groups comparisons, college students having mental disorder background had worse mental health than those without such a background. However, in the within-subject comparisons, no statistically significant changes occurred across time in the mental health of college students having mental disorder history. Conversely, significant changes occurred in those without such a background, but only when the interaction between time and quarantine duration was considered. Worsening mental health occurred during the most heavily restrictive quarantine phases, while some of the remissions occurred during the longest, but less restrictive ones.

Lithium in drinking water, altitude, and suicide rates in rural areas of Argentinean Andes.

The Lithium Triangle in the Andean plateau involves high altitude (>3,000 m asl) hydrological systems having high lithium graded waters. This research was carried-out in rural areas of north westernmost Argentinean Andes and was aimed: 1) to determine concentrations of lithium in drinking waters; 2) to calculate suicide mortality rates based on available official data (2003-2013); 3) to analyze bivariate differences between lithium concentrations in drinking water, mean rates of suicide mortality, altitude of sampling sites, and water sources; 4) to analyze bivariate correlations between lithium concentrations in drinking water, mean rates of suicide mortality, and altitude; 5) to test predictive models for mean rates of suicide mortality, when considering the predictors lithium concentrations in drinking water, altitude, and water sources. Lithium determinations in drinking waters were performed by Microwave Plasma-Atomic Emission Spectrometer. Nonparametric tests were applied to analyze differences and correlations. Generalized linear models (GLM) were used to fitting models for mean rates of suicide. Drinking waters contained up to 2.98 mg L-1 of lithium. Mean rates of suicide mortality (per 100,000 inhabitants) were high, ranging from 19.12 (± 19.83) to 30.22 (± 16.70). Lithium but not altitude was positively correlated with suicide mortality when analyzing bivariate correlations (Li: rho = 0.76, p-value < 0.001). However, when GLM were calculated, a significant interaction effect was found between lithium and altitude (p-value < 0.001). This interaction effect would act in some way restraining the suicide mortality rates.

Altitude and latitude variations in trait-impulsivity, depression, anxiety, suicidal risk, and negative alcohol-related consequences in Argentinean adolescents.

The aims of this research were threefold: 1) to analyze mental health state both general (GMHS, i.e., self-perceived health and psychological distress) and specific (SMHS; i.e., depression, trait-anxiety, negative alcohol-related consequences, and suicidal risk), and impulsivity-related traits (i.e., negative urgency, positive urgency, [lack of] perseverance, [lack of] premeditation, and sensation seeking) in a sample of Argentinean adolescent college students, in function of sex (women, men) and three different altitude-latitude regions (high-north, middle-center, low-south), for identifying common and specific features; 2) to analyze relationships between impulsivity-related traits and indicators of GMHS and SMHS, in the entire sample and in each altitude-latitude region, for understanding the importance of impulsivity-related traits in these forms of mental disorders; and 3) to analyze bivariate relationships between depression, trait-anxiety, negative alcohol-related consequences, and suicidal risk, in the entire sample and considering the three altitude-latitude regions, for testing two-disorder comorbidities. Scores on impulsivity-related traits differed by sex and by altitude-latitude region. GMHS and SMHS differed by sex but not by altitude-latitude region. Several relationships were found between impulsivity-related traits, GMHS, and SMHS as well as between indicators of SMHS. Some of these relationships were dependent on altitude-latitude regions, and implications of these findings were discussed.

[Temporal, socio-demographic and diagnostic profile of psychologically assisted cases at an Emergency Medical Service - Jujuy.] / Perfil temporal, sociodemográfico e diagnóstico de casos atendidos psicológicamente en Servicio de Guardia general - Jujuy.

AIM: The objective of this study was to know temporal, socio-demographic and diagnostic features of psychologically assisted patients at the General Emergency Service of the major hospital in Jujuy. METHODS: The study was transversal (01/20/2018 to 09/13/2018). Temporal, socio-demographic and diagnostic variables (according to ICD-10) were analyzed in 657 cases. For data analysis RStudio was used. Frequencies and descriptive statistics were reported. We evaluated differences in age according to sex (women-men) and according to age categories (adolescents-adults) with Wilcoxon Test, and differences in diagnostic clusters according to sex and age with Kruskal-Wallis Test. The type I error was set at ≤ 0.05. RESULTS: Cases assisted during weekends prevailed. From the total, 57.53% were women. The mean age in both sexes was 34.35 years (±15.08; Median = 32). A decreasing pattern of cases from younger to older age groups were found. There were no differences in age according to sex (p-value = 0.22), but they were differences according to age categories (p-value < 0.001). Cases with single marital status and employment were prevalent. The prevalent general diagnostic groups were: Neurotic, stress-related and somatoform disorders (31.51%); Disorders due to psychoactive substance use (12.48%); Intentional self-harm (10.20%); Assault (9.59%). CONCLUSIONS: We present the first diagnostic profile of mental health emergency-assisted casuistry in Jujuy. We highlight the need to design prevention strategies for alcohol and other psychoactive substances related disorders, aimed primarily at adolescents and young people. We discuss further implications of the results.

Objetivo: Este estudio tuvo como objetivo conocer características temporales, sociodemográficas y diagnósticas de usuarios asistidos psicológicamente en el Servicio de Guardia general del principal hospital de Jujuy. Métodos: El estudio fue transversal (20/01/18 al 13/09/18). Se analizaron variables temporales, sociodemográficas y diagnósticas (según la CIE-10) en 657 casos. Para los análisis de datos se usó RStudio. Se informaron frecuencias y estadísticos descriptivos. Se evaluaron diferencias en edad según sexo (mujeres-varones) y según categorías de edad (adolescentes-adultos) con prueba de Wilcoxon y diferencias en agrupaciones diagnósticas según sexo y edad con prueba de Kruskal-Wallis. El error tipo I se fijó en ≤ 0.05. Resultados: Prevalecieron los casos asistidos durante fines de semana. Del total, el 57.53% fueron mujeres. La media de edad en ambos sexos fue de 34.35 años (±15.08; Mediana = 32). Hubo un patrón decreciente de casos desde franjas etarias menores a mayores. No hubo diferencias en edad según sexo (p-valor = 0.22), pero sí según categorías de edad (p-valor < 0.001). Prevalecieron casos con estado civil soltero y ocupación laboral. Las agrupaciones diagnósticas generales prevalentes fueron: Trastornos neuróticos, relacionados con el estrés y somatomorfos (31.51%); Trastornos debidos al uso de sustancias psicoactivas (12.48%); Lesiones autoinfligidas intencionalmente (10.20%); Agresiones (9.59%). Conclusiones: Se presenta el primer perfil diagnóstico de casuística asistida por urgencias en salud mental en Jujuy. Se destaca la necesidad de diseñar estrategias de prevención para trastornos relacionados con alcohol y otras sustancias, dirigidas principalmente a adolescentes y jóvenes. Se discuten otras implicancias de los resultados presentados.

Waste into rivers: a residual issue? The case of the UNESCO's site of the Quebrada De Humahuaca, NW Argentina.

The Quebrada de Humahuaca in North West Argentina is a world heritage site listed by the UNESCO since 2003. As pollution is increasing dramatically, a pluridisciplinary, annual-long survey was conducted along the valley to determine dominant patterns in waste management and water quality. Along with the habit of discarding waste into the river, urbanizations have been identified as having a deep influence on the river water quality: iron together with maximum peaks of nitrite and nitrate are related with the anthropogenic activity at Humahuaca, whereas the concentrations of arsenic increase from north to south, with maximum peaks of up to 13.50 and 14.50 µg L-1 measured during the rainy season at Maimará and Volcán, respectively. In this underdeveloped region, economic struggles and waste management customs revealed as major factors causing the environmental degradation. The inclusion in the UNESCO's sites list was insufficient in preserving this world heritage site. The approach discussed in this article suggests a straightforward analytical measurement of the river hydrochemical properties during the rainy season in arid/semi-arid regions with monsoonal regime, to assess the effects of waste dumping along watercourses. In addition to scientific evaluations, both public acceptance and the establishment of proper waste management infrastructure are fundamental to ensuring the preservation of human and environmental health.

General Mental Health State Indicators in Argentinean Women During Quarantine of up to 80-Day Duration for COVID-19 Pandemic.

Introduction: Argentinean quarantine during the COVID-19 pandemic is one of the most long-lasting worldwide. We focused on the first 80-days of this quarantine on Argentinean women. Our aims were to analyze differences in general mental health state (MHS) indicators, by the (1) sites of residence with different prevalence of COVID-19 cases, and (2) quarantine duration; (3) to assess multiple relationships between each general MHS indicator and potentially affecting factors. Methods: We used a cross-sectional design with convenience successive sampling (N = 5,013). The online survey included a socio-demographic questionnaire (elaborated ad hoc) with standardized and validated self-reported questionnaires (General Health Questionnaire, Kessler Psychological Distress Scale) measuring the MHS indicators: self-perceived health, psychological discomfort, social functioning and coping, and psychological distress. Results: Worse self-perceived health and higher psychological discomfort affected significantly more women residing in sites with high prevalence of COVID-19 cases, compared to those residing in sites with intermediate prevalence, but effect sizes were small. Mean scores of all general MHS indicators were significantly worse for longer quarantine sub-periods (up to 53, 68, and 80-day duration) than for shorter sub-periods (up to seven, 13, and 25-day duration). Being a younger age, having mental disorder history, and longer quarantine durations were associated to worsening MHS, while the lack of previous suicide attempt has a protective effect. Discussion: Our findings show that a worse MHS during quarantine may not be attributed to the objective risk of contagion (measured greater or less), and under quarantine, women MHS-as indicated by group central tendency measures-got worse as time went by. This strongly suggests that special attention needs to be paid to younger women and to women with history of mental disorder. Along with physical health, mental health must be a priority for the Government during and after quarantine and the COVID-19 pandemic.

Is unemployment less important than expected for suicide attempted in developing regions? Occupational profile of suicide attempts in Jujuy, north westernmost Argentina.

BACKGROUND: Mental health practices consider unemployment as a suicide main risk factor, based on models built for populations of developed countries. AIM: This study assesses the association between the occupational risk factor and suicidal behaviors, by considering sex, age and temporal distribution, in a Latin American Andean population from north westernmost Argentina. METHODS: Data include 481 suicide attempt cases assisted by emergency service psychologists at a head hospital in the Jujuy Province, northern Argentina, during two biennials. General categories and specific types of occupational situation, sex, age and temporal distribution were analyzed. RESULTS: 83.58% of cases corresponded to the with occupation category, but without occupation characterized male cases (p-value = .01). The type no referred occupation (19.15%) mainly contributed to this association (p-value = .02). Unemployed only represented 1.6%. These features revealed independent from the biennial period of assistance (p-value = .96 (general), p-value = .86 (specific)). Associations by age ranges did not seem to be specific of suicidal attempts. CONCLUSION: The present contribution provides an occupational characterization of suicide attempts in an Andean population from north westernmost Argentina. Unemployment is not associated with suicidal behavior in this population, suggesting that dissimilar patterns underlie suicidal behavior of populations from developed and developing regions.

Lithium and Boron in Calcified Tissues of Vicuna and Their Relation to Chronic Exposure by Water Ingestion in The Andean Lithium Triangle.

Vicuna is a wild, endangered species of Andean camelid living in the hyperarid Andean plateau. In the central part of the plateau, the Lithium Triangle defines a zone with lithium-rich salt pans. Brine pools naturally form within the salt pans, and the adaptation strategy of vicuna consists of drinking from brine pools. Together with reporting the first chemical data on vicuna bones and teeth, we analyzed lithium, boron, and arsenic in water and brines, with the aim of assessing their relation to chronic exposure by water ingestion. We collected and analyzed bones of vicuna specimens lying in an Andean salt pan, together with brine and water samples. Brine and water samples are highly saline and contain large amounts of lithium, boron, and arsenic. Lithium (13.50-40 mg kg-1 ) and boron (40-46.80 mg kg-1 ), but not arsenic, were found in the vicuna bones and teeth. Based on our results and on previously reported data on human tissues in the Andes, we conducted statistical assessments of the relationships between lithium and boron in body tissues and water samples, and discuss their environmental significance in the context of the Lithium Triangle. Environ Toxicol Chem 2019;39:200-209. © 2019 SETAC.

Estimación de riesgo carcinógeno por exposición crónica al arsénico a través del agua de consumo en la Puna, Jujuy / Estimation of Carcinogenic Risk due to Chronic Exposure to Arsenic via Water for Human Consumption in Puna, Jujuy

INTRODUCCIÓN: La ingesta crónica de arsénico (As) se asocia con cáncer. Se sabe que las cuencas hídricas de la Puna de Jujuy contienen As y que muchos hogares no tienen agua potable de red, pero aún no se había estimado el riesgo carcinógeno para los pobladores por ingerir el agua local. OBJETIVOS: Estimar el nivel de riesgo carcinógeno para los pobladores locales debido a exposición crónica al As a través del agua de bebida. MÉTODOS: Se determinaron las concentraciones de As en muestras de agua de consumo de poblados de Cochinoca, Susques y Tumbaya con espectroscopía de emisión atómica de plasma acoplado inductivamente. Se calculó el riesgo carcinógeno con modelos matemáticos de la United States Environmental Protection Agency. RESULTADOS: Se halló As en todas las muestras (rango 0,041-0,34 mg/l/As), y el 83% superó el máximo permitido para agua potable (0,05 mg/l/As). Según las concentraciones medias de As por departamento, el riesgo carcinógeno para los pobladores estuvo entre 2,44 x 10-3 y 5,89 x 10-3. El riesgo carcinógeno para quienes consumen agua potable de red fue de 2,36 x 10-3 y para quienes consumen agua de otras procedencias, de 4,76 x 10-3. Todos los valores hallados superaron el máximo de aceptabilidad del riesgo asociado a la exposición a un carcinógeno (10-5). CONCLUSIONES: Es necesario implementar programas de comunicación de riesgos y políticas en salud para disminuir riesgos debidos a ingesta de agua con contenidos arsenicales en esta región.

Marcadores temporales de riesgo supuesto en casos asistidos psicológicamente en un Servicio de Guardia: descripción de sus distribuciones y confrontación de la hipótesis de asociación entre temporalidad y conductas suicidas / Supposed risk temporal markers, in cases psychologically assisted in an Emergency Service: description of their distributions, and confrontation of the hypothesis of association between temporality and suicidal behaviors

Se estudió la distribución temporal de casos asistidos psicológicamente en Servicio de Guardia de un hospital público de Jujuy durante un periodo cuatrienal. En función del tipo de motivo de consulta, el total de casos se dividió en dos muestras: intento de suicidio, y otro motivo de consulta psicológica. Se analizaron los marcadores temporales: periodo total, bienios, años, estaciones, meses y días de atención. Se puso a prueba la independencia-asociación entre marcadores temporales de riesgo y tipos de motivo de consulta. Se halló un aumento significativo de intento suicida como motivo de consulta psicológica del primer al segundo bienio estudiado. Marcadores temporales, tales como estaciones, meses y días de atención, no caracterizaron específica ni diferencialmente a intento suicida respecto de otro motivo de consulta psicológica en urgencias.

It was studied the temporal distribution of psychologically assisted cases at Emergency Service of a public hospital of Jujuy Province during a quadrennial period. Depending on the type of complaint, the total cases were divided into two samples: suicide attempt, and another reason for psychological consultation. The temporal markers, total period, biennium, years, seasons, months, and days of assistance were analyzed. The independence-correlation between risk temporal markers and types of consultation it was tested. It was found a significant increase in suicide attempts as reason for psychological consultation from the first to the second biennium studied. Temporal markers, such as seasons, months and days of assistance, not characterized or specifically or differentially suicide attempt over another reason for psychological consultation in emergency.