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Rev. patol. respir ; 21(4): 135-137, oct.-dic. 2018. ilus
Article in Spanish | IBECS | ID: ibc-178304

ABSTRACT

Presentamos el caso clínico de una paciente en tratamiento corticoideo crónico que desarrolla infección pulmonar por citomegalovirus y Aspergillus. Tras el ingreso la paciente presenta empeoramiento radiológico y clínico, por lo que ante la posibilidad de infecciones oportunistas dado el tratamiento previo con corticoides a dosis altas de forma prolongada se decide el inicio con antimicrobianos de amplio espectro, con cobertura para hongos, virus y bacterias. Posteriormente, la estabilización de la paciente permitió la realización de pruebas diagnósticas confirmando una coinfección por Aspergillus fumigatus y citomegalovirus, con lo que se pudo realizar un tratamiento dirigido tras el cual la paciente presenta recuperación completa tanto clínica como radiológica, sin complicaciones por toxicidades farmacológicas. Aunque algunos autores dudan sobre el uso de varios antimicrobianos de forma empírica debido a las posibles toxicidades, en situaciones urgentes sin diagnostico con sospecha de patología oportunista puede ser necesaria su cobertura


We present the clinical case of a patient in chronic corticosteroid treatment who develops lung infection with Cytomegalovirus and Aspergillus. After admission, the patient presented with radiological and clinical worsening, with the suspect of opportunistic infections because of previous prolonged treatment with high doses of corticosteroids, we decided to start with broad-spectrum antimicrobials, covering fungi, viruses and bacteria. Subsequently, the stabilization of the patient allowed the performing of diagnostic tests wich confirming a coinfection by Aspergillus fumigatus and Cytomegalovirus, making possible to carry out a directed treatment after which the patient presented complete recovery both clinical and radiological, without complications due to pharmacological toxicities. Although some authors doubt about the use of multiples antimicrobials drugs at the same time empirically due to the possible toxicities, in emergency without diagnosis and suspected opportunistic pathology their coverage may be necessary


Subject(s)
Humans , Female , Aged , Pulmonary Aspergillosis/diagnostic imaging , Pulmonary Aspergillosis/drug therapy , Cytomegalovirus Infections/diagnostic imaging , Cytomegalovirus Infections/drug therapy , Coinfection/drug therapy , Adrenal Cortex Hormones/therapeutic use , Coinfection/diagnostic imaging , Opportunistic Infections/complications , Opportunistic Infections/drug therapy , Radiography, Thoracic , Bronchoscopy/methods
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