[Prevalence of HPV high-risk serotypes detected by PCR in patients with normal cervical cytology at the Hospital Regional Adolfo López Mateos, ISSSTE]. / Prevalencia de genotipos de alto riesgo de VPH detectados por PCR en pacientes con citología normal del Hospital Regional Adolfo López Mateos, ISSSTE.

Background: Is fundamental to determine the prevalence of human papiloma virus (HVP) high-risk serotypes in local and regional population in order for health providers to offer patients, vaccines and treatments against specific population-based serotypes. Objetive: To determine the prevalence of HPV High risk serotypes detected by PCR in patients with normal cytology from the ISSSTE Adolfo Lopez Mateos Regional Hospital. Methods: An observational, descriptive, prospective study was conducted from cervical cytologies and high risk HPV test by PCR in patients from the Regional Hospital Adolfo López Mateos, ISSSTE, during the period January 2013-December 2015. Cases of patients with negative cervical cytology were included. Information about age, the result of cervical cytology and high risk HPV test by PCR was obtained. The overall prevalence of HPV infection and the most prevalent serotypes by age groups were calculated. Results: A total of 3258 cervical smears were performed, of which 2557 were negative (78.4%), from this, the global prevalence of HPV infection was 10.2% (n=262). We found that 1.8% (n = 45) of negative reports had HPV16 infection, 0.5% (n=13) had HPV18 and 8.9% (n = 227) were infected by Viral Pool of other high-risk serotypes. The prevalence of infection by viral pool of high risk serotypes was 11.5% in women <20 years, 12.9% in women between 20-29 years and 22.2% in women between 30-39 years. This prevalence was lower in patients older than 40 years (p<0.05). Conclusion: A higher prevalence of viral pool high risk serotypes was found in patients with normal cytology, than the HPV16 and HPV-8 prevalence, which was significantly higher in women younger than 40 years.

[Electrosurgery as treatment of high grade squamous intraepithelial lesions of the cervix]. / Electrocirugía como tratamiento de las lesiones intraepiteliales escamosas de alto grado del cérvix.

A prospective study was realized with the purpose of evaluating the efficiency of the excisional therapy of the electrosurgery in the treatment of the High Grade Squamous Intraepithelial Lesion (H.G.S.L.I.) of the cervix. 149 patients who were attended at the colposcopy service with this diagnosis were selected during September 1990 to April 1993. The procedure was realized in 37 patients 24.8% in the operating room and in 112 patients (75.2% in the outpatient room with local anaesthesia. With this last mentioned method in 93.8% not one type of trouble was presented, referring only a slightly to moderate pain in 6.2%. The transoperatory complications were bleeding on the surgical site in 3.3% which was solved at the moment through local electrocoagulation, and late bleeding present in 4.2% of the patients. The lesion was completely eliminated when the deepness of the cone corresponded to 1.81 cm in 139 cases (93.29%). Through a colpo-cytologic follow-up in 24 months, a persistence of the virus of the human papilloma was shown in 5.5% during the first nine months and appearance of one case of H.G.S.I.L. after 18 months. Therefore, these results had a therapeutic efficiency of the global follow-up of 90.08%.