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1.
Dermatology ; 194(4): 358-60, 1997.
Article in English | MEDLINE | ID: mdl-9252757

ABSTRACT

A case of cutaneous malakoplakia in an 81-year-old woman in reported. A reddish slowly growing plaque had appeared on her forehead 13 years previously. Histopathology revealed a dense dermal granulomatous infiltrate consisting of lymphocytes and numerous histiocytes containing Michaelis-Gutmann bodies. Ciprofloxacin treatment resulted in partial involution of the lesion.


Subject(s)
Facial Dermatoses/pathology , Malacoplakia/pathology , Aged , Aged, 80 and over , Anti-Infective Agents/therapeutic use , Ciprofloxacin/therapeutic use , Facial Dermatoses/diagnosis , Facial Dermatoses/drug therapy , Female , Forehead , Humans , Malacoplakia/diagnosis , Malacoplakia/drug therapy
2.
Dermatology ; 195(1): 52-3, 1997.
Article in English | MEDLINE | ID: mdl-9267740

ABSTRACT

We report a patient with multiple sclerosis who was receiving subcutaneous injections of recombinant interferon beta. During the third month of treatment, painful necrotizing cutaneous lesions appeared at the injection sites. The possible pathogenesis of interferon-induced skin necrosis is discussed.


Subject(s)
Adjuvants, Immunologic/adverse effects , Interferon-beta/adverse effects , Multiple Sclerosis/therapy , Skin/pathology , Adjuvants, Immunologic/administration & dosage , Adult , Erythema/etiology , Female , Humans , Injections, Subcutaneous , Interferon-beta/administration & dosage , Necrosis , Recombinant Proteins
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