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1.
Curr Osteoporos Rep ; 16(6): 775-778, 2018 12.
Article in English | MEDLINE | ID: mdl-30393831

ABSTRACT

The human fibula responds to its mechanical environment differently from the tibia accordingly with foot usage. Fibula structure is unaffected by disuse, and is stronger concerning lateral bending in soccer players (who evert and rotate the foot) and weaker in long-distance runners (who jump while running) with respect to untrained controls, along the insertion region of peroneus muscles. These features, strikingly associated to the abilities of the fibulae of predator and prey quadrupeds to manage uneven surfaces and to store elastic energy to jump, respectively, suggest that bone mechanostat would control bone properties with high selective connotations beyond structural strength.


Subject(s)
Bone Density/physiology , Exercise/physiology , Fibula/physiology , Stress, Mechanical , Biomechanical Phenomena , Humans
2.
Fortschr Neurol Psychiatr ; 82(5): 267-70, 2014 May.
Article in German | MEDLINE | ID: mdl-24824204

ABSTRACT

Frontotemporal dementia remains a diagnostic challenge. Especially the differential diagnosis between FTD and affective disorders is often difficult. Based on a case report, diagnostic efforts and differential diagnoses are described and revisited criteria for the behavioral FTD (bvFTD) from Rascowsky et al. are mentioned.


Subject(s)
Frontotemporal Dementia/diagnosis , Aged , Diagnosis, Differential , Electroencephalography , Frontotemporal Dementia/epidemiology , Humans , Magnetic Resonance Imaging , Male , Mood Disorders/etiology , Mood Disorders/psychology , Neuropsychological Tests
3.
Nature ; 458(7240): 868-71, 2009 Apr 16.
Article in English | MEDLINE | ID: mdl-19370029

ABSTRACT

The phenomenon of spin resonance has had far-reaching influence since its discovery 70 years ago. Electron spin resonance driven by high-frequency magnetic fields has enhanced our understanding of quantum mechanics, and finds application in fields as diverse as medicine and quantum information. Spin resonance can also be induced by high-frequency electric fields in materials with a spin-orbit interaction; the oscillation of the electrons creates a momentum-dependent effective magnetic field acting on the electron spin. Here we report electron spin resonance due to a spin-orbit interaction that does not require external driving fields. The effect, which we term ballistic spin resonance, is driven by the free motion of electrons that bounce at frequencies of tens of gigahertz in micrometre-scale channels of a two-dimensional electron gas. This is a frequency range that is experimentally challenging to access in spin resonance, and especially difficult on a chip. The resonance is manifest in electrical measurements of pure spin currents-we see a strong suppression of spin relaxation length when the oscillating spin-orbit field is in resonance with spin precession in a static magnetic field. These findings illustrate how the spin-orbit interaction can be harnessed for spin manipulation in a spintronic circuit, and point the way to gate-tunable coherent spin rotations in ballistic nanostructures without external alternating current fields.

4.
Phys Rev Lett ; 98(19): 196805, 2007 May 11.
Article in English | MEDLINE | ID: mdl-17677648

ABSTRACT

Compressibility measurements are performed on a quantum point contact (QPC). Screening due to mobile charges in the QPC is measured quantitatively, using a second point contact. These measurements are performed from pinch-off through the opening of the first few modes in the QPC. While the measured signal closely matches a Thomas-Fermi-Poisson prediction, deviations from the classical behavior are apparent near the openings of the different modes. Density functional calculations attribute the deviations to a combination of a diverging density of states at the opening of each one-dimensional mode and exchange interaction, which is strongest for the first mode.

5.
Nature ; 413(6858): 822-5, 2001 Oct 25.
Article in English | MEDLINE | ID: mdl-11677600

ABSTRACT

Quantum mechanical experiments in ring geometries have long fascinated physicists. Open rings connected to leads, for example, allow the observation of the Aharonov-Bohm effect, one of the best examples of quantum mechanical phase coherence. The phase coherence of electrons travelling through a quantum dot embedded in one arm of an open ring has also been demonstrated. The energy spectra of closed rings have only recently been studied by optical spectroscopy. The prediction that they allow persistent current has been explored in various experiments. Here we report magnetotransport experiments on closed rings in the Coulomb blockade regime. Our experiments show that a microscopic understanding of energy levels, so far limited to few-electron quantum dots, can be extended to a many-electron system. A semiclassical interpretation of our results indicates that electron motion in the rings is governed by regular rather than chaotic motion, an unexplored regime in many-electron quantum dots. This opens a way to experiments where even more complex structures can be investigated at a quantum mechanical level.

6.
Phys Rev Lett ; 86(10): 2118-21, 2001 Mar 05.
Article in English | MEDLINE | ID: mdl-11289869

ABSTRACT

Coulomb blockade resonances are measured in a GaAs quantum dot in which both shape deformations and interactions are small. The parametric evolution of the Coulomb blockade peaks shows a pronounced pair correlation in both position and amplitude, which is interpreted as spin pairing. As a consequence, the nearest-neighbor distribution of peak spacings can be well approximated by a modified bimodal Wigner surmise, in which interactions are taken into account beyond the constant interaction model.

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