1.
Farmaco Sci
; 31(7): 471-7, 1976 Jul.
Article
in English
| MEDLINE
| ID: mdl-947778
ABSTRACT
A series of 1-hydroxypyrrolidin-2-ones (v) has been prepared by reduction of gamma-nitrocarboxylic acid esters with Zn dust in the presence of ammonium chloride. Acylation of compounds (v) gave the corresponding 1-acyloxypyrrolidin-2-ones (VI). None of the synthesized compounds showed any significant antiflammatory activity.