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Ann Pharm Fr ; 48(6): 321-5, 1990.
Article in French | MEDLINE | ID: mdl-2131764

ABSTRACT

A new route to 2-N-(carboxypropylamino)-2-deoxy-D-glucopyranose synthesis is reported, involving the Schiff-base derivative of beta-D-glucosamine with benzyl 4-oxobutyrate. Improvement in the synthesis of benzyl-4-oxobutyrate is also described. Biological compounds action was investigated by evaluating sedative and dopaminergic activities on male mice.


Subject(s)
Deoxyglucose/analogs & derivatives , gamma-Aminobutyric Acid/analogs & derivatives , Animals , Deoxyglucose/chemical synthesis , Dopamine Antagonists , Hypnotics and Sedatives/antagonists & inhibitors , Male , Mice
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