Subject(s)
MELAS Syndrome/complications , Stroke/etiology , Adult , Brain/pathology , Humans , MELAS Syndrome/pathology , Magnetic Resonance Imaging , Male , Stroke/pathologyABSTRACT
A case of a 30-year-old male with a fever, dry cough and associated abnormal findings in imaging modalities (bilateral hilar lymphadenopathy and nodular parenchymal opacities) is described. After a further and scrutinized work-up, the diagnosis of GLUS syndrome was made. Clinical, etiological, pathological and therapeutical aspects of the disease are discussed, demonstrating the paramount importance of the use of the immunohistochemical methods in the diagnosis of this disorder.
Subject(s)
Granuloma/diagnosis , Lung Diseases/diagnosis , Lymphatic Diseases/diagnosis , Adult , Granuloma/diagnostic imaging , Humans , Lung Diseases/diagnostic imaging , Lymphatic Diseases/diagnostic imaging , Male , Tomography, X-Ray ComputedABSTRACT
BACKGROUND: Congenital bronchial atresia is a rare anomaly, which usually occurs in adulthood as an incidental finding on routine chest radiograph. METHODS: The purpose of the study was to retrospectively evaluate the cases that were diagnosed in our hospital, from January 1995 to March 2003, to estimate the prevalence of this disorder and to determine the diagnostic studies of choice, according to the existing literature. Since the main portion of the male population of our country is referred to our hospital for screening soon after their enrollment in the army, epidemiological data can be easily estimated for many congenital anomalies occuring in adulthood, such as bronchial atresia. RESULTS: We found seven patients with Congenital Bronchial Atresia and the prevalence of this disorder was estimated at 1.2 cases per 100,000 in males. The chosen diagnostic procedure is computed tomography of the chest with high-resolution scans. Bronchoscopy would only exclude serious alternative diagnosis and prevent unnecessary surgical interventions. CONCLUSIONS: Congenital bronchial atresia is a rare anomaly, with a mild clinical course. The diagnosis is made radiologically, the HRCT of the chest being the procedure of choice. Bronchoscopy should be performed to exclude any endobronchial lesion due to a different disease entity and to prevent unnecessary surgical intervention in an otherwise asymptomatic individual.
Subject(s)
Bronchi/abnormalities , Adult , Bronchoscopes , Hospitals, Military , Humans , Male , Middle Aged , Prevalence , Respiratory Function Tests , Respiratory System Abnormalities/diagnosis , Respiratory System Abnormalities/epidemiology , Retrospective Studies , Tomography, X-Ray ComputedABSTRACT
A 19-yr-old male presented with left lung parahilar consolidation and clinical signs of pneumonia. These symptoms were secondary to an endobronchial mass in the apical segment of the lower lobe. At thoracotomy an apical segment bronchial sleeve resection successfully extirpated what later proved to be an endobronchial eosinophilic granuloma. To the authors' knowledge this is the first case report of an endobronchial eosinophilic granuloma in an adult.
Subject(s)
Bronchial Diseases/diagnosis , Eosinophilic Granuloma/diagnosis , Lung Diseases/diagnosis , Adult , Diagnosis, Differential , Humans , Male , Tomography, X-Ray ComputedABSTRACT
A 19 year old man presented with a six months history of dyspnoea on exertion. Chest radiographs, isotopic lung scans, and computed tomographic scans of the chest showed unilateral translucency of the left lung, absence of ventilation and perfusion in the same lung, and a 3.5 cm aneurysm of the descending thoracic aorta which compressed the left mainstem bronchus.
