ABSTRACT
The paper present a clinic and histological study, including all cases of uveal malignant tumours, hospitalized in Ophthalmological Clinic of Craiova in the last 15 years. The follow-up period of cases were 4 years. The diagnosis was established by clinic and paraclinic examination (imaging methods-- MRI, CT, Echo) and histologic examination. The histologic examination has been done for all cases. There were investigated several parametres: tumour cytology, the level of pigmentation, intravascular embolus, sclera infiltration, vascular invasion, vascular pattern, tumoral necrosis, mitotic activity. The histologic aspects of tumoral progression were: the high level mitotic activity, high surface area of intratumoral necrosis, the infiltrative process to the vessels, sclera, and ciliary body. The arcuat and network vascular patterns were involved in the systemic metastasis and local invasion. The most predominant type of cellularity related with a severe evolution of cases were the epithelioid cells and the mixed type cells.
Subject(s)
Melanoma/diagnosis , Uveal Neoplasms/diagnosis , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Male , Melanoma/pathology , Melanoma/surgery , Middle Aged , Retrospective Studies , Uveal Neoplasms/pathology , Uveal Neoplasms/surgeryABSTRACT
The paper realized the retrospective evaluation of all cases of neovascular glaucoma hospitalized in Clinic of Ophthalmology of Craiova in the last 15 years. Neovascular secondary glaucoma represents 3,9% of all glaucomas. The most important etiologic factors were the central venous occlusion, diabetic retinopathy, carotid occlusion, intraocular tumors, chronic uveitis, Fuchs heterochromy. Neovascular secondary glaucoma is characterized by important hypoxic tissues destructions, presented of all levels that lead to neovessels formation with irreversible anatomic and functional losing of ocular globe. The identification of neovascular glaucoma causes and their treatment is important to prevent that diseases.
