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1.
JCO Oncol Pract ; : OP2400267, 2024 May 31.
Article in English | MEDLINE | ID: mdl-38820470

ABSTRACT

A personalized commentary promoting use of the chair in Inpatient Oncology.

2.
Alcohol Alcohol ; 56(3): 368-375, 2021 Apr 29.
Article in English | MEDLINE | ID: mdl-32812034

ABSTRACT

AIMS: Alcoholic hepatitis (AH) and alcoholic cirrhosis disproportionately affect ethnic minority and safety-net populations. We evaluate the impact of a hospital's safety net burden (SNB) on in-hospital mortality and costs among patients with AH and alcoholic cirrhosis. METHODS: We performed a cross-sectional analysis of 2012-2016 National Inpatient Sample. SNB was calculated as percentage of hospitalizations with Medicaid or uninsured payer status. Associations between hospital SNB and in-hospital mortality and costs were evaluated with adjusted multivariable logistic regression and linear regression models. RESULTS: Among 21,898 AH-related hospitalizations, compared to low SNB hospitals (LBH), patients hospitalized in high SNB hospitals (HBH) were younger (44.4 y vs. 47.4 y, P < 0.001) and more likely to be African American (11.3% vs. 7.7%, P < 0.001) or Hispanic (15.4% vs. 8.4%, P < 0.001). AH-related hospitalizations in HBH had a non-significant trend towards higher odds of mortality (OR 1.27, 95% CI 0.98-1.65, P = 0.07) and higher mean hospitalizations costs. Among 108,669 alcoholic cirrhosis-related hospitalizations, patients in HBH were younger (53.3 y vs. 55.8 y, P < 0.001) and more likely to be African American (8.2% vs. 7.3%, P < 0.001) or Hispanic (24.4% vs. 12.0%, P < 0.001) compared to LBH. Compared to alcoholic cirrhosis-related hospitalizations in LBH, mortality was higher among medium SNB (OR 1.10, 95% CI 1.03-1.17, P = 0.007) and HBH (OR 1.07, 95% CI 1.00-1.15, P = 0.05). Mean hospitalization costs were not different by SNB status. CONCLUSIONS: HBH hospitals predominantly serve ethnic minorities and underinsured/uninsured populations. The higher in-hospital mortality associated HBH particularly for alcoholic cirrhosis patients is alarming given its increasing burden in the USA.


Subject(s)
Hepatitis, Alcoholic/mortality , Hospital Mortality , Liver Cirrhosis, Alcoholic/mortality , Safety-net Providers , Aged , Cross-Sectional Studies , Female , Hepatitis, Alcoholic/ethnology , Hospitalization , Humans , Insurance Coverage , Liver Cirrhosis, Alcoholic/ethnology , Male , Middle Aged , Retrospective Studies , United States
3.
J Clin Gastroenterol ; 54(3): 218-226, 2020 03.
Article in English | MEDLINE | ID: mdl-31913877

ABSTRACT

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide and remains one of the most rapidly rising cancers among the US adults. While overall HCC survival is poor, early diagnosis via timely and consistent implementation of routine HCC surveillance among at-risk individuals leads to earlier tumor stage at diagnosis, which is directly correlated with improved options for potentially curative therapies, translating into improved overall survival. Despite this well-established understanding of the benefits of HCC surveillance, surveillance among cirrhosis patients remains suboptimal in a variety of practice settings. While the exact reasons underlying the unacceptably low rates of routine HCC surveillance are complex, it likely reflects multifactorial contributions at the patient, provider, and health care system levels. Furthermore, these multilevel challenges affect ethnic minorities disproportionately, which is particularly concerning given that ethnic minorities already experience existing barriers in timely access to consistent medical care, and these populations are disproportionately affected by HCC burden in the United States. In this review, we provide an updated evaluation of the existing literature on rates of HCC surveillance in the United States. We specifically highlight the existing literature on the impact of patient-specific, provider-specific, and health care system-specific factors in contributing to challenges in effective implementation of HCC surveillance.


Subject(s)
Carcinoma, Hepatocellular , Healthcare Disparities , Liver Neoplasms , Adult , Carcinoma, Hepatocellular/diagnosis , Carcinoma, Hepatocellular/epidemiology , Ethnicity , Humans , Liver Cirrhosis , Liver Neoplasms/diagnosis , Liver Neoplasms/epidemiology , United States/epidemiology
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