Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Gynecol Obstet Invest ; 79(3): 210-6, 2015.
Article in English | MEDLINE | ID: mdl-25765014

ABSTRACT

OBJECTIVE: This study compares hysteroscopic and histopathological results in postmenopausal women with abnormal uterine bleeding (AUB) and asymptomatic postmenopausal women with a thickened endometrium. MATERIALS AND METHODS: This is a retrospective study of 570 cases hysteroscopically examined between January 2008 and July 2012. The patients were followed up at the Istituto Tumori 'Giovanni Paolo II', Bari, Italy. RESULTS: A total of 320 of the 570 cases were selected. The inclusion criteria were transvaginal ultrasound, hysteroscopy and endometrial biopsy. In the AUB group, if the hysteroscopy results were normal, a sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 100, 95, 71 and 100%, respectively, were achieved, while in the asymptomatic group these values were 100, 97, 90 and 100%, respectively. For both the group with polyps and that with myomas, the sensitivity, specificity, PPV and NPV were 100%. For endometrial hyperplasia, hysteroscopy showed a sensitivity, specificity, PPV and NPV of 81, 96, 87 and 93%, respectively, in the AUB group, while in the asymptomatic group, the sensitivity was 60%, the specificity and PPV were 100%, and the NPV was 98%. The sensitivity of hysteroscopy for endometrial cancer was 63%, the specificity 97%, the PPV 77%, and the NPV 95%. CONCLUSIONS: In postmenopausal women with a thickened endometrium with or without AUB, hysteroscopy allows for an accurate diagnosis in benign endometrial pathology. Hysteroscopy also allows directed biopsies of suspicious lesions, which is useful in malignant endometrial pathology.


Subject(s)
Endometrial Hyperplasia/diagnosis , Endometrium/pathology , Hysteroscopy/methods , Uterine Hemorrhage/diagnosis , Uterine Neoplasms/diagnosis , Aged , Aged, 80 and over , Endometrial Hyperplasia/pathology , Female , Follow-Up Studies , Humans , Italy , Middle Aged , Postmenopause , Retrospective Studies , Sensitivity and Specificity , Uterine Neoplasms/pathology
2.
Reprod Biomed Online ; 15(6): 686-91, 2007 Dec.
Article in English | MEDLINE | ID: mdl-18062866

ABSTRACT

The effect of myomectomy on implantation and pregnancy rates prior to assisted reproduction treatments is controversial. This study was designed to assess clinical outcomes of IVF cycles in women with uterine fibroids. A retrospective single-centre assessment of clinical outcomes of IVF/intracytoplasmic sperm injection (ICSI) treatments in infertile women in a 4-year span was carried out. All patients underwent detailed transvaginal ultrasound and hysteroscopy to precisely identify presence, location and intracavitary growth of uterine fibroids. Cumulative pregnancy, ongoing pregnancy and live birth rates were considered primary outcome measurements. Fifty-one women with fibroids (97 treatment cycles), 63 patients with previous myomectomy (127 cycles), and 106 infertile women who did not demonstrate fibroids anywhere in the uterus (215 cycles) were considered for the analysis. No significant difference was found for pregnancy and live birth rates between groups. Women with fibroids>4 cm required an increased number of cycles to obtain an ongoing pregnancy, compared with the other groups. The data do not support pre-IVF myomectomy in women with small-to-moderate uterine fibroids, regardless of their location. This represents valuable information in the counselling of women with fibroids before reproductive assisted cycles.


Subject(s)
Fertilization in Vitro , Infertility, Female/therapy , Leiomyoma/complications , Pregnancy Outcome , Uterine Neoplasms/complications , Adult , Female , Humans , Infertility, Female/complications , Laparoscopy , Laparotomy , Leiomyoma/diagnostic imaging , Leiomyoma/surgery , Pregnancy , Retrospective Studies , Sperm Injections, Intracytoplasmic , Ultrasonography , Uterine Neoplasms/diagnostic imaging , Uterine Neoplasms/surgery
SELECTION OF CITATIONS
SEARCH DETAIL
...