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1.
J Occup Environ Hyg ; 15(11): 773-781, 2018 11.
Article in English | MEDLINE | ID: mdl-30156970

ABSTRACT

Surgical smoke resulting from electrocauterization is a health risk for operating room personnel. The U.S. National Institute for Occupational Safety and Health recommends the use of local exhaust ventilation such as a portable smoke evacuation system to reduce surgical smoke, but its efficiency has never been assessed under experimental conditions. In this study, particle filtration efficiencies of five commercially available smoke evacuation systems were investigated in a model operating room. Two cutting angles, the devices' suction capacities, three unidirectional displacement flow rates, and the noise exposures were considered. Results demonstrated that portable smoke evacuation systems reduce surgical smoke up to 99% under optimal conditions. A cutting angle of 45°, the device's maximum suction capacity, and a unidirectional displacement flow rate of 10,500 m³/hr were advantageous. Sound levels ranged between 51-69 dBA and exceeded recommended threshold limits, if used with medium or maximum suction capacity. Hence, portable smoke evacuation systems are beneficial and are recommended. However, a combination with general unidirectional room ventilation and a strict limitation of the use of electrocauterization is strongly advised.


Subject(s)
Electrocoagulation/adverse effects , Noise, Occupational , Occupational Exposure/prevention & control , Operating Rooms , Air Pollutants, Occupational/analysis , Electrocoagulation/methods , Filtration/methods , Occupational Exposure/analysis , Smoke , Ventilation/methods
2.
World J Surg Oncol ; 15(1): 5, 2017 Jan 05.
Article in English | MEDLINE | ID: mdl-28056985

ABSTRACT

BACKGROUND: Dermatofibrosarcoma protuberans (DFSP) is a cutaneous soft tissue sarcoma characterized by an indolent but aggressive local growth. Unplanned excisions with positive margins are common, and the prognostic impact of radical re-excisions is still unclear. The aim of the present study was to identify prognostic indicators of recurrence-free survival (RFS) in patients with DFSP through a long-term follow-up. We tried particularly to determine the prognostic impact of surgical margins and re-excisions in patients after earlier inadequate surgery. METHODS: Seventy-five patients with DFSP were treated surgically at our institution between 1999 and 2015. Analyses were restricted to 68 participants with available information on surgical margins. The median follow-up was 5.4 years. RESULTS: Fifty-four patients (79.4%) had low-grade DFSP and 14 patients (20.6%) intermediate-grade FS-DFSP. The 5-year RFS rates were estimated to be 93.5% (95% CI 81.2-97.9) for low-grade DFSP and 39.7% (95% CI 13.0-65.8) for FS-DFSP (P < 0.0001). Re-excisions were performed in 55 patients (80.9%) following R1 or marginal R0 resections. Negative margins could be attained in a total of 65 patients (95.6%). Negative margin widths >1 cm led to the best local outcome within the R0 subgroup. Significant adverse prognostic features in the multivariate analysis included histologic grade and close margins. CONCLUSIONS: The data from this study underscore the long-term benefit of negative margins. In our analysis, re-excisions were an effective method to achieve a high rate of local control in patients who presented after R1 or marginal R0 resection. To ensure the best outcome, re-excisions should aim at negative margin widths of more than 1 cm in the histologic specimen.


Subject(s)
Dermatofibrosarcoma/surgery , Neoplasm Recurrence, Local/surgery , Reoperation , Skin Neoplasms/surgery , Dermatofibrosarcoma/pathology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Neoplasm Grading , Neoplasm Recurrence, Local/pathology , Prognosis , Retrospective Studies , Skin Neoplasms/pathology , Survival Rate
3.
Am J Infect Control ; 40(7): e228-32, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22542026

ABSTRACT

BACKGROUND: Wound infections present one of the most prevalent and frequent complications associated with surgical procedures. This study analyzes the impact of currently used ventilation systems in the operating room to reduce bacterial contamination during surgical procedures. METHODS: Four ventilation systems (window-based ventilation, supported air nozzle canopy, low-turbulence displacement airflow, and low-turbulence displacement airflow with flow stabilizer) were analyzed. Two hundred seventy-seven surgical procedures in 6 operating rooms of 5 different hospitals were analyzed for this study. RESULTS: Window-based ventilation showed the highest intraoperative contamination (13.3 colony-forming units [CFU]/h) followed by supported air nozzle canopy (6.4 CFU/h; P = .001 vs window-based ventilation) and low-turbulence displacement airflow (3.4 and 0.8 CFU/h; P < .001 vs window-based ventilation and supported air nozzle canopy). The highest protection was provided by the low-turbulence displacement airflow with flow stabilizer (0.7 CFU/h), which showed a highly significant difference compared with the best supported air nozzle canopy theatre (3.9 CFU/h; P < .001). Furthermore, this system showed no increase of contamination in prolonged durations of surgical procedures. CONCLUSION: This study shows that intraoperative contamination can be significantly reduced by the use of adequate ventilation systems.


Subject(s)
Air Microbiology , Bacteria/isolation & purification , Bacterial Load , Operating Rooms , Ventilation/methods , Humans
4.
Plast Reconstr Surg ; 127(4): 1539-1545, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21187812

ABSTRACT

BACKGROUND: A primary strategy for preventing and treating wound infection in chronic wounds is the use of topical antiseptics and wound irrigating agents. However, their interaction with commonly used wound dressings has not yet been investigated. In this study, the authors analyzed the antimicrobial activity of antiseptics and wound irrigating agents used with commercially available wound dressings. METHODS: Five clinically used antiseptics and wound irrigating agents (Prontosan, Lavasept, Braunol, Octenisept, and Betaisodona) were tested in the presence or absence of 42 wound dressings against Staphylococcus aureus. The determination of antibacterial activity was performed by disk diffusion assay. RESULTS: Povidone-iodine-based products showed sufficient antimicrobial activity in 64 to 78 percent of the combinations assessed (p > 0.01). The octenidine derivate Octenisept showed sufficient antimicrobial activity in 54 percent of combinations. Polyhexamethylene biguanide derivatives demonstrated sufficient antimicrobial activity in 32 percent of the combinations. CONCLUSION: This study revealed that commonly used wound dressings dramatically reduce antibacterial activity of clinically used antiseptics and wound irrigating agents in vitro.


Subject(s)
Anti-Infective Agents, Local/pharmacology , Bandages , Staphylococcus aureus/drug effects , Therapeutic Irrigation , Wound Infection/prevention & control , Biguanides/pharmacology , Imines , In Vitro Techniques , Microbial Sensitivity Tests , Povidone-Iodine/pharmacology , Pyridines/pharmacology , Staphylococcus aureus/growth & development , Wound Infection/microbiology
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