Subject(s)
Sleep Apnea Syndromes/epidemiology , Tinnitus/complications , Adult , Aged , Chronic Disease , Continuous Positive Airway Pressure , Humans , Male , Middle Aged , Prevalence , Severity of Illness Index , Sex Factors , Sleep Apnea Syndromes/diagnosis , Sleep Apnea Syndromes/therapy , Tinnitus/diagnosisSubject(s)
Hormone Replacement Therapy , Menopause , Tinnitus/drug therapy , Age Factors , Chronic Disease , Contraceptives, Oral, Synthetic/therapeutic use , Estrogens/therapeutic use , Estrogens, Conjugated (USP)/therapeutic use , Female , Humans , Medroxyprogesterone/therapeutic use , Middle Aged , Retrospective StudiesABSTRACT
Objective:To explore the hormone treatment outcome of the menopause related tinnitus.Method:From April 2016 to October 2016, Fifty-nine patients who were diagnosed with menopausal syndrome in the menopause clinics of Beijing Shijitan Hospital were enrolled in our study, and questionnaire-based investigation about tinnitus and menopause was performed. According to the patients' intention, they were divided into treatment group and control group. Age, BMI, menopausal KMI scores, severity of tinnitus were statistically analyzed. After 3 months follow up, the different therapeutic effects of tinnitus between two groups were analyzed. Result:There was no significant difference between two groups in age, BMI, menopausal KMI scores and severity of tinnitus. The tinnitus in untreated patients after 3 months follow up showed no improvement, while 5 cases had been cured in treatment group. Conclusion:Menopause related tinnitus was an independent type of tinnitus. Menopausal hormone therapy can be applied for treatment after excluding other tinnitus risk factors.
Subject(s)
Menopause , Tinnitus/therapy , Aged , Female , Humans , Middle Aged , Risk Factors , Surveys and Questionnaires , Treatment OutcomeABSTRACT
BACKGROUND: Retrosigmoid vestibular neurectomy is suggested to be the most effective and safe procedure to control intractable vertigo associated with Ménière's disease. The purpose of this study is to report the excellent efficacy of vertigo control, the good preservation of hearing, the rare complications and the simplicity of retrosigmoid vestibular neurectomy performed by an interdisciplinary team of neurosurgery and otorhinolaryngology experts of our teaching hospital. METHODS: Seventy-three patients with Ménière's disease who were refractory to medication or other surgical therapy were consecutively operated on over a period of 7 years. All the patients were referred to the senior author (CSL) for the surgery and were followed-up by the same neurootologist (JTL). The retrosigmoid approach for selective vestibular neurectomy was the only surgical method used in our neurosurgical facility. During surgery the separation line was made just at the cochleo-vestibular cleavage plane on the cochlear nerve to achieve a more complete sectioning of the vestibular fibres. To ensure accurate and complete data collection, patient data was prospectively entered into an electronic database, which was used subsequently for analysis of vertigo control, preservation of hearing, improvement in functional levels, and surgical complications. RESULTS: Long-term excellent and good vertigo control were achieved in 69 (94.5%) and 4 (5.5%) patients respectively. Hearing was preserved to within 10 dB of the pre-operative pure-tone thresholds in 91.8% of patients at 1 month after the surgery. The functional levels improved to level 1 by a reduction of 3-5 points and became stabilised by 2 years of follow-up in all of our patients. No patient was worse post-operatively. Complications were uncommon and included superficial wound infection and transient partial facial paralysis in one patient each. Total hearing loss did not occur post-operatively. The mean operating time was 70 min. CONCLUSION: Selective vestibular neurectomy via the retrosigmoid approach is an effective and simple neurosurgical procedure for the control of intractable vertigo in Ménière's disease while preserving hearing.
Subject(s)
Denervation/methods , Meniere Disease/surgery , Neurosurgery , Otolaryngology , Patient Care Team , Vestibular Nerve/surgery , Adult , Aged , Denervation/adverse effects , Disability Evaluation , Female , Follow-Up Studies , Hearing , Humans , Male , Meniere Disease/complications , Meniere Disease/physiopathology , Middle Aged , Postoperative Period , Retrospective Studies , Speech Perception , Tinnitus/etiology , Tinnitus/physiopathology , Treatment Outcome , Vertigo/etiologyABSTRACT
OBJECTIVE: To assess the accuracy rate associated with 11-gauge vacuum assisted large-core breast biopsy (VALCBB) at our institution. METHODS: 673 consecutive VALCBBs performed between September 1997 and March 2000 were evaluated. For most of the benign VALCBB specimens, accuracy was determined by the stability of the lesions on follow-up mammography. When possible, histological results of specimens obtained from VALCBB and of specimens obtained from surgical excision were compared. Modified accuracy rates were calculated. RESULTS: Of the 673 biopsies, 499 (74%) were benign; for the 315 benign lesions for which complete follow-up information was available, a greater than 99% modified accuracy rate was obtained. The modified accuracy rate for the 174 nonbenign lesions was 95%. Thus, VALCBB yielded an overall modified accuracy for both benign and nonbenign lesions of 97.9%. CONCLUSION: VALCBB provides accurate histological results for biopsy of suspicious lesions of the breast.
Subject(s)
Biopsy/methods , Breast/pathology , Biopsy/standards , Breast Neoplasms/pathology , Canada , Female , Follow-Up Studies , Humans , Mammography , Sensitivity and Specificity , Stereotaxic TechniquesABSTRACT
OBJECTIVE: To assess both the rate and types of complications associated with vacuum-assisted large-core breast biopsy (VALCBB) at our institution. METHODS: Three hundred and four VALCBBs performed in 297 patients between Sept. 18, 1997, and Mar. 30, 1999, were evaluated. Complications associated with VALCBB were assessed at the time of the procedure and in the post-procedure period. Adverse outcomes included pain, bleeding or bruising, and hematoma. Complications were also classified in terms of minor, significant, and major severity. RESULTS: VALCBB yielded non-minor (i.e., significant and major) complication rates of 3.9% during the procedure and 3.6% in the post-procedure period, with only 2 complications (vasovagal-induced seizure and migraine) that required treatment. CONCLUSION: With proper technique and patient preparation, VALCBB is a very safe procedure with a low complication rate.
