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J Clin Microbiol ; 41(9): 4400-3, 2003 Sep.
Article in English | MEDLINE | ID: mdl-12958276

ABSTRACT

In the course of characterizing 103 rotaviruses from children in Mexico, we found that the majority of strains were globally common types (55.4% of total), while uncommon types represented 5.7%, mixed infections with common types represented 14.8%, and partially or fully nontypeable isolates represented about 24%. Serotype G9 was detected for the first time in Mexico. We sequenced a subset of strains that were G nontypeable by reverse transcriptase PCR and found surprisingly that two strains having common human rotavirus P genotypes (8 and 6) had serotype G3 and G4 VP7 gene sequences that shared closer homology with canine and porcine strains, respectively, than with human strains, suggesting that these isolates represented reassortants between human and animal rotaviruses.


Subject(s)
Antigens, Viral , Capsid Proteins/genetics , Dogs/virology , Rotavirus/classification , Swine/virology , Animals , Base Sequence , Child , Genotype , Humans , Mexico , Molecular Sequence Data , RNA, Viral/analysis , Reassortant Viruses/genetics , Rotavirus/genetics
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