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Ann Endocrinol (Paris) ; 37(3): 171-88, 1976.
Article in French | MEDLINE | ID: mdl-1020917

ABSTRACT

The morphological functional and electrophysiologic findings of the report of olfactory gonadic dysplasia are reviews. The 11 cases are then presented with the analysis and interpretation of the EEG traces (17), as well as studies of olfactory activation of the EEF (6 subjects) and of afternoon sleep polygraphy (2 subjects). There is discussion of the possible sites of dysfunction in the mesencephalic-limbic structures which could be the source either directly or indirectly of the EEG modifications. Certain EEG abnormalities (interhemispheric asymmetry) alow the consideration that the pathogenetic mechanisms of the syndrome began during ontogenesis (in 5 of 11 subjects). Thereby suggesting that an electrophysiologic examination can be a valuable tool to pick up olfactory gonadic dysplasia early and to follow the hormonal treatment in the confirmed cases.


Subject(s)
Central Nervous System/physiopathology , Cerebral Cortex/physiopathology , Hypogonadism/physiopathology , Olfaction Disorders/physiopathology , Olfactory Pathways/physiopathology , Adolescent , Adult , Electroencephalography , Female , Humans , Hypogonadism/complications , Male , Middle Aged , Olfaction Disorders/complications , Sleep
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