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2.
Phys Rev E ; 106(1-1): 014128, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35974641

ABSTRACT

The Fredkin spin chain serves as an interesting theoretical example of a quantum Hamiltonian whose ground state exhibits a phase transition between three distinct phases, one of which violates the area law. Here we consider a classical stochastic version of the Fredkin model, which can be thought of as a simple exclusion process subject to additional kinetic constraints, and study its classical stochastic dynamics. The ground-state phase transition of the quantum chain implies an equilibrium phase transition in the stochastic problem, whose properties we quantify in terms of numerical matrix product states (MPSs). The stochastic model displays slow dynamics, including power-law decaying autocorrelation functions and hierarchical relaxation processes due to exponential localization. Like in other kinetically constrained models, the Fredkin chain has a rich structure in its dynamical large deviations-which we compute accurately via numerical MPSs-including an active-inactive phase transition and a hierarchy of trajectory phases connected to particular equilibrium states of the model. We also propose, via its height field representation, a generalization of the Fredkin model to two dimensions in terms of constrained dimer coverings of the honeycomb lattice.

3.
Phys Rev Lett ; 128(24): 246603, 2022 Jun 17.
Article in English | MEDLINE | ID: mdl-35776467

ABSTRACT

The dynamics of spin at finite temperature in the spin-1/2 Heisenberg chain was found to be superdiffusive in numerous recent numerical and experimental studies. Theoretical approaches to this problem have emphasized the role of nonabelian SU(2) symmetry as well as integrability, but the associated methods cannot be readily applied when integrability is broken. We examine spin transport in a spin-1/2 chain in which the exchange couplings fluctuate in space and time around a nonzero mean J, a model introduced by De Nardis et al. [Phys. Rev. Lett. 127, 057201 (2021).PRLTAO0031-900710.1103/PhysRevLett.127.057201]. We show that operator dynamics in the strong noise limit at infinite temperature can be analyzed using conventional perturbation theory as an expansion in J. We find that regular diffusion persists at long times, albeit with an enhanced diffusion constant. The finite time spin dynamics is analyzed and compared with matrix product operator simulations.

4.
Genome Biol ; 22(1): 346, 2021 12 20.
Article in English | MEDLINE | ID: mdl-34930412

ABSTRACT

Multimodal data is rapidly growing in many fields of science and engineering, including single-cell biology. We introduce MultiMAP, a novel algorithm for dimensionality reduction and integration. MultiMAP can integrate any number of datasets, leverages features not present in all datasets, is not restricted to a linear mapping, allows the user to specify the influence of each dataset, and is extremely scalable to large datasets. We apply MultiMAP to single-cell transcriptomics, chromatin accessibility, methylation, and spatial data and show that it outperforms current approaches. On a new thymus dataset, we use MultiMAP to integrate cells along a temporal trajectory. This enables quantitative comparison of transcription factor expression and binding site accessibility over the course of T cell differentiation, revealing patterns of expression versus binding site opening kinetics.


Subject(s)
Chromosome Mapping/methods , Single-Cell Analysis/methods , Transcriptome , Algorithms , Chromatin , Chromosomes, Human , Gene Expression Regulation , Genetic Markers , Genomics , Humans , Software , Transcription Factors
5.
Entropy (Basel) ; 23(9)2021 Aug 31.
Article in English | MEDLINE | ID: mdl-34573759

ABSTRACT

The Schrödinger bridge problem (SBP) finds the most likely stochastic evolution between two probability distributions given a prior stochastic evolution. As well as applications in the natural sciences, problems of this kind have important applications in machine learning such as dataset alignment and hypothesis testing. Whilst the theory behind this problem is relatively mature, scalable numerical recipes to estimate the Schrödinger bridge remain an active area of research. Our main contribution is the proof of equivalence between solving the SBP and an autoregressive maximum likelihood estimation objective. This formulation circumvents many of the challenges of density estimation and enables direct application of successful machine learning techniques. We propose a numerical procedure to estimate SBPs using Gaussian process and demonstrate the practical usage of our approach in numerical simulations and experiments.

6.
Phys Rev Lett ; 126(10): 100603, 2021 Mar 12.
Article in English | MEDLINE | ID: mdl-33784115

ABSTRACT

Dual-unitary quantum circuits can be used to construct 1+1 dimensional lattice models for which dynamical correlations of local observables can be explicitly calculated. We show how to analytically construct classes of dual-unitary circuits with any desired level of (non-)ergodicity for any dimension of the local Hilbert space, and present analytical results for thermalization to an infinite-temperature Gibbs state (ergodic) and a generalized Gibbs ensemble (nonergodic). It is shown how a tunable ergodicity-inducing perturbation can be added to a nonergodic circuit without breaking dual unitarity, leading to the appearance of prethermalization plateaux for local observables.

7.
Phys Rev Lett ; 120(9): 090401, 2018 Mar 02.
Article in English | MEDLINE | ID: mdl-29547309

ABSTRACT

We study a system of spins (qubits) coupled to a common noisy environment, each precessing at its own frequency. The correlated noise experienced by the spins implies long-lived correlations that relax only due to the differing frequencies. We use a mapping to a non-Hermitian integrable Richardson-Gaudin model to find the exact spectrum of the quantum master equation in the high-temperature limit and, hence, determine the decay rate. Our solution can be used to evaluate the effect of inhomogeneous splittings on a system of qubits coupled to a common bath.

8.
Science ; 347(6219): 232-3, 2015 Jan 16.
Article in English | MEDLINE | ID: mdl-25593172
9.
Phys Rev Lett ; 107(24): 240601, 2011 Dec 09.
Article in English | MEDLINE | ID: mdl-22242982

ABSTRACT

We discuss the unusual critical behavior of a generalized XY model containing both 2π-periodic and π-periodic couplings between sites, allowing for ordinary vortices and half-vortices. The phase diagram of this system includes both single-particle condensate and pair-condensate phases. Using a field theoretic formulation and worm algorithm Monte Carlo simulations, we show that in two dimensions it is possible for the system to pass directly from the disordered (high temperature) phase to the single particle (quasi)condensate via an Ising transition, a situation reminiscent of the "deconfined criticality" scenario.

10.
Phys Rev Lett ; 101(22): 225301, 2008 Nov 28.
Article in English | MEDLINE | ID: mdl-19113488

ABSTRACT

We consider the motion of a spin-1/2 impurity in a one-dimensional gas of spin-1/2 fermions. For antiferromagnetic interaction between the impurity and the fermions, the low temperature behavior of the system is governed by the two-channel Kondo effect, leading to the impurity becoming completely opaque to the spin excitations of the gas. As well as the known spectral signatures of the two-channel Kondo effect, we find that the low temperature mobility of the resulting "Kondo polaron" takes the universal form mu-->3variant Planck's over vF2/2pikB2T2, in sharp contrast to the spinless case where mu proportional variant T(-4).

11.
Phys Rev Lett ; 100(16): 165706, 2008 Apr 25.
Article in English | MEDLINE | ID: mdl-18518223

ABSTRACT

The probability distribution of the order parameter is expected to take a universal scaling form at a phase transition. In a spin system at a quantum critical point, this corresponds to universal statistics in the distribution of the total magnetization in the low-lying states. We obtain this scaling function exactly for the ground state and first excited state of the critical quantum Ising spin chain. This is achieved through a remarkable relation to the partition function of the anisotropic Kondo problem, which can be computed by exploiting the integrability of the system.

12.
Phys Rev Lett ; 98(16): 160404, 2007 Apr 20.
Article in English | MEDLINE | ID: mdl-17501399

ABSTRACT

We discuss the ordering of a spin-1 condensate when quenched from its paramagnetic phase to its ferromagnetic phase by reducing the magnetic field. We first elucidate the nature of the equilibrium quantum phase transition. Quenching rapidly through this transition reveals XY ordering either at a specific wave vector, or the "light-cone" correlations familiar from relativistic theories, depending on the end point of the quench. For a quench proceeding at a finite rate the ordering scale is governed by the Kibble-Zurek mechanism. The creation of vortices through growth of the magnetization fluctuations is also discussed. The long-time dynamics again depends on the end point, conserving the order parameter in a zero field, but not at a finite field, with differing exponents for the coarsening of magnetic order. The results are discussed in the light of a recent experiment by Sadler et al.

13.
Phys Rev Lett ; 94(13): 136801, 2005 Apr 08.
Article in English | MEDLINE | ID: mdl-15904016

ABSTRACT

We develop the general nonequilibrium theory of transport through a quantum dot, including Coulomb blockade effects via a 1/N expansion, where N is the number of scattering channels. At lowest order we recover the Landauer formula for the current plus a self-consistent equation for the dot potential. We obtain the leading corrections and compare with earlier approaches. Finally, we show that to leading and to next leading order in 1/N there is no interaction correction to the weak localization, in contrast to previous theories, but consistent with experiments by Huibers et al. [Phys. Rev. Lett. 81, 1917 (1998)], where N=4.

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