Queratitis fúngica por Colletotrichum gloeosporioides resistente a tratamiento / Treatment resistant fungal keratitis caused by Colletotrichum gloeosporioides

CASO CLÍNICO: Mujer de 56 años, que sufrió un traumatismo con rama de naranjo en el ojo izquierdo. Durante 40 días después desarrolla una infección ocular positiva para Colletotrichum gloeosporioides (C. gloeosporioides). El paciente no respondió al tratamiento clásico ni al cross-linking y tuvo que ser mediante queratoplastia con complicaciones intraoperatorias y postoperatorias. DISCUSIÓN: Las infecciones oculares por Colletotrichum gloeosporioides pueden ser refractarias al tratamiento tradicional así como a nuevas terapias como el cross-linking

CASE REPORT: A 56 year old woman suffered corneal injury from a branch of an orange tree. Forty days later she suffered a severe ocular infection, positive to Colletotrichum gloeosporioides (C. gloeosporioides). The patient did not respond to traditional treatment or crosslinking, and had to be treated with keratoplasty, suffering intraoperative and postoperative complications. DISCUSSION: Ocular infections due to C. gloeosporioides can occasionally be refractory to traditional and new treatments, such as crosslinking

Treatment resistant fungal keratitis caused by Colletotrichum gloeosporioides.

CASE REPORT: A 56 year old woman suffered corneal injury from a branch of an orange tree. Forty days later she suffered a severe ocular infection, positive to Colletotrichum gloeosporioides (C. gloeosporioides). The patient did not respond to traditional treatment or crosslinking, and had to be treated with keratoplasty, suffering intraoperative and postoperative complications. DISCUSSION: Ocular infections due to C. gloeosporioides can occasionally be refractory to traditional and new treatments, such as crosslinking.

[Paraneoplastic subacute cerebellar degeneration: case report]. / Degeneração cerebelar subaguda paraneoplásica: relato de caso.

We report a 40-year-old woman with subacute cerebellar degeneration associated with ovarian cancer. We briefly review the clinical and laboratory features of this syndrome, and emphasize the importance of its prompt recognition, which many times makes possible the early detection and treatment of the primary disorder.

Toxic neuropathy after adenine arabinoside treatment in chronic HBsAg-positive liver disease.

A 62-year-old woman with hepatitis-B-surface-antigen-positive hepatic cirrhosis presented with weakness and paresthesias over the distal part of the limbs in the course of adenine arabinoside 5'-monophosphate (ARA-AMP) treatment, and recovered spontaneously after several weeks of drug withdrawal. Electrophysiological and histological studies demonstrated axonal neuropathy. Although the patient received a relatively low total dose (120 mg/kg), her age and advanced liver disease may have played a role in the ARA-AMP neurotoxicity.

Diffuse axonal injury after severe head trauma. A clinico-pathological study.

Diffuse Axonal Injury (DAI) is a well known entity that affects many patients with severe head trauma. Classically DAI has been considered the pathological substrate of those cases rendered unconscious at the moment of impact and in which the CT scan does not show mass lesions. Diffuse axonal damage is almost always related to mechanisms of injury in which the rotational acceleration produces shear and tensile strains of high magnitude. In this paper we present a group of 24 patients with a severe head injury in whom the postmortem examination demonstrated unequivocal signs of DAI. Widespread axonal retraction balls, located preferentially in the centrum semiovale and internal capsule were the most constant histological finding. We divided the entire series into two subgroups. One group (15 cases), included all the patients in whom the CT scan did not demonstrate mass lesions. In the second group (9 patients) we considered patients with a diffuse axonal injury in whom the CT scan additionally demonstrated a mass lesion (6 acute subdural haematomas, 2 intracerebral and 1 extradural haematoma). The mean age of the entire group was 26 years. Twenty two patients were injured in a road traffic accident, the remaining two fell from a considerable height. All were rendered immediately unconscious on impact. Diffuse brain damage is a common finding in patients with a severe head injury and immediate coma in whom the CT scan does not show mass lesions. Diffuse axonal injury can also appear in connection with a wide spectrum of focal lesions (acute subdural haematoma, basal ganglia haematoma etc.).(ABSTRACT TRUNCATED AT 250 WORDS)

Mononeuritis multiplex in Waldenström's macroglobulinemia.

We describe a patient with mononeuritis multiplex who had cranial nerve involvement in association with Waldenström's macroglobulinemia. Sural nerve biopsy showed abundant endoneurial granulofibrillary deposits related to microangiopathic changes. These changes were distributed in a multifocal pattern among the fascicles. Immunohistochemistry demonstrated the IgM nature of the deposit located in the endoneurial interstitium.

Hydrocephalus: an unusual CT presentation of cerebral toxoplasmosis in a patient with acquired immunodeficiency syndrome.

We describe a case of central nervous system (CNS) toxoplasmosis in a patient with acquired immunodeficiency syndrome (AIDS). Supratentorial hydrocephalus as a result of aqueductal collapse was the only abnormal finding on computed tomography scan. Toxoplasma gondii is the most common pathogen organism in high-risk AIDS's patients with involvement of the CNS.