Video games and board games: Effects of playing practice on cognition.

The worldwide popularity of playing practices has led to a growing research interest in games' impact on behavior and cognition. Many studies have already reported the benefits of both video games and board games for cognitive functions. However, these studies have mainly defined the term players according to a minimum play time or in connection to a specific game genre. No study has confronted the cognitive implications of video games and board games in the same statistical model. Thus, it remains unclear whether the cognitive benefits of play are due to play time or game type. To address this issue, in this study, we conducted an online experiment in which 496 participants completed six cognitive tests and a playing practice questionnaire. We examined the between the participants' overall video game and board game play times and cognitive abilities. The results demonstrated significant relations between overall play time and all cognitive functions. Importantly, video games significantly predicted mental flexibility, planning, visual working memory, visuospatial processing, fluid intelligence, and verbal working memory performance, while board games were not found to predict any cognitive performance. These findings suggest that video games affect cognitive functions in specific ways compared to board games. We encourage further investigation to consider players' individual differences through their play time and the specific features of the games they play.

Exploring the connection between work-family conflict and job burnout among Nigerian correctional staff.

Only one study among U.S. prison staff has explored the effects of work-family conflict and job burnout. To replicate the research to determine whether the results vary by nation, this study examined the effects of four types of work-family conflict (strain-based, time-based, behavior-based and family-based conflict) on three dimensions of job burnout (emotional exhaustion, depersonalization and feeling ineffective at work) among Nigerian correctional staff. Strain- and behavior-based conflict had significant positive effects on emotional exhaustion, but time- and family-based conflict did not. Family-based conflict was the only type of domain spillover with significant positive effects on depersonalization. Behavior-based conflict was the only type of work-family conflict with significant positive effects on feeling ineffective at work. Time-based and strain-based conflict were highly related to one another, which was attributed to time-based conflict being a contributor to strain-based conflict for Nigerian prison staff.

Morphological processing in written word production is based on orthography rather than semantics.

Written word production is influenced by central and peripheral processes. Evidence suggests that the activation of morphological units in the lexicon influences the dynamics of handwriting. In this study, we designed two priming experiments to examine the representation level of morphological information in the lexicon during written word production in the French language. In both experiments, target words (e.g., chanteur, "singer") were primed by a derived (e.g., chanter, "to sing"), a pseudo-derived (e.g., chantier, "work site"), or an unrelated (e.g., baleine, "whale") prime. We used the pseudo-derivation condition to disentangle two distinct levels of representation: the sublexical (also known as morpho-orthographic) and the supralexical (morpho-semantic). In Experiment 1 (learning-recall task), we measured the writing latency and writing duration of the target words. In Experiment 2 (word pair copying task), we measured the inter-word duration and writing duration of the target words. We observed morphological priming effects in both experiments: The processing of a derived prime influenced target writing compared to an unrelated prime, but the effect was observed on latencies in Experiment 1 and on target writing duration in Experiment 2. We found similar patterns of priming in the derived and pseudo-derived conditions in both experiments. The findings revealed that morphemes are processed at the morpho-orthographic representation level in written word production. Morphemes serve as grouping units during handwriting, a process that operates independently of their meaning.

Modeling the influence of motor skills on literacy in third grade: Contributions of executive functions and handwriting.

Several nonlanguage factors influence literacy development, and motor skills are among those most studied. Despite the publication of several studies that have supported the existence of this relationship, the type of influence and underlying mechanisms have been little explored. Herein, we propose modeling the relationship between motor skills and literacy through structural equation modeling, testing the contribution of executive functions and handwriting skills as the possible mediators of this relationship. In a study of 278 third-grade children, we used a wide range of measures related to written language (reading, spelling, reading comprehension, and written production), fine motor skills (dominant hand, nondominant hand, and bimanual dexterity), executive functions (verbal and visuospatial working memory, inhibition, and shifting), and handwriting. Structural equation modeling of the relationship between these different variables indicated that in the third grade, the influence of fine motor skills on literacy is fully mediated by both executive functions and handwriting skills. These motor skills effects are observed for both low levels of processing (reading, spelling) and high levels of processing (reading comprehension, written production). The results are discussed in terms of the potential mechanisms underlying different literacy skills and their implications for pedagogical programs.

ChronoRoot: High-throughput phenotyping by deep segmentation networks reveals novel temporal parameters of plant root system architecture.

BACKGROUND: Deep learning methods have outperformed previous techniques in most computer vision tasks, including image-based plant phenotyping. However, massive data collection of root traits and the development of associated artificial intelligence approaches have been hampered by the inaccessibility of the rhizosphere. Here we present ChronoRoot, a system that combines 3D-printed open-hardware with deep segmentation networks for high temporal resolution phenotyping of plant roots in agarized medium. RESULTS: We developed a novel deep learning-based root extraction method that leverages the latest advances in convolutional neural networks for image segmentation and incorporates temporal consistency into the root system architecture reconstruction process. Automatic extraction of phenotypic parameters from sequences of images allowed a comprehensive characterization of the root system growth dynamics. Furthermore, novel time-associated parameters emerged from the analysis of spectral features derived from temporal signals. CONCLUSIONS: Our work shows that the combination of machine intelligence methods and a 3D-printed device expands the possibilities of root high-throughput phenotyping for genetics and natural variation studies, as well as the screening of clock-related mutants, revealing novel root traits.

Quality by design approach identifies critical parameters driving oxygen delivery performance in vitro for perfluorocarbon based artificial oxygen carriers.

Perfluorocarbons (PFCs) exhibiting high solubility for oxygen are attractive materials as artificial oxygen carriers (AOC), an alternative to whole blood or Haemoglobin-based oxygen carriers (HBOCs). PFC-based AOCs, however, met clinical translation roadblocks due to product quality control challenges. To overcome these issues, we present an adaptation of Quality by Design (QbD) practices to optimization of PFC nanoemulsions (PFC-NEs) as AOCs. QbD elements including quality risk management, design of experiments (DoE), and multivariate data analysis facilitated the identification of composition and process parameters that strongly impacted PFC colloidal stability and oxygen transport function. Resulting quantitative relationships indicated a composition-driven tradeoff between stability and oxygen transport. It was found that PFC content was most predictive of in vitro oxygen release, but the PFC type (perfluoro-15-crown-5-ether, PCE or perfluorooctyl bromide, PFOB) had no effect on oxygen release. Furthermore, we found, under constant processing conditions, all PFC-NEs, comprised of varied PFC and hydrocarbon content, exhibited narrow droplet size range (100-150 nm) and narrow size distribution. Representative PFOB-NE maintained colloidal attributes upon manufacturing on larger scale (100 mL). QbD approach offers unique insights into PFC AOC performance, which will overcome current product development challenges and accelerate clinical translation.

The Association of Organizational Justice with Job Satisfaction and Organizational Commitment among Nigerian Correctional Staff.

Correctional staff are a necessary and valuable resource for correctional institutions, in both Western and Nonwestern nations; however, studies of correctional staff in Nonwestern nations, particularly those in Africa, are lacking. Improving the job satisfaction and organizational commitment of these staff are imperative, as both of these job attitudes have been linked to many salient beneficial outcomes. Most of the existing empirical research on correctional staff organizational justice explores only the effects of procedural and distributive justice and ignores interpersonal justice. Additionally, there has been little research on how procedural, distributive, and interpersonal justice affect correctional staff in Nonwestern correctional organizations. The current study explored the effects of all three forms of organizational justice on the job satisfaction and organizational commitment of staff at a medium security prison in southeast Nigeria. Based on Ordinary Least Squares (OLS) regression, all three forms of justice had significant positive effects on commitment. Procedural and interpersonal justice had positive effects on job satisfaction, while distributive justice had nonsignificant effects. Correctional administrators need to be aware the importance of procedural, distributive, and interpersonal justice and attempt to improve perceptions of these organizational justice variables.

Rhythm in the blood: The influence of rhythm skills on literacy development in third graders.

Several studies have shown the influence of rhythm skills on the processing of written language, especially at the beginning of literacy development. The first objective of this study was to determine the persistence of this link at an advanced grade level. The second objective was to better understand the factors underlying this relationship and, more specifically, to examine the hypothesis of mediation by phonological and/or motor skills. In total, 278 third graders performed literacy tasks (word/pseudoword decoding and spelling), a rhythm production task, two phonological tasks (phonological awareness and rapid automatized naming), and motor tasks. Significant correlations were observed between literacy and each of rhythm skills, phonological skills, and motor skills. However, structural equation models showed that the influence of rhythm skills on literacy was mediated neither by phonological skills nor by motor abilities. These results suggest that rhythm skills continue to play a role in the acquisition of written language in third graders and that this contribution seems to be independent of phonological and motor skills.

The Effects of Inmate Medical Issues on Correctional Staff Job Involvement and Organizational Commitment.

In the United States, institutional corrections is a major undertaking that requires substantial financial resources. Correctional staff are the essential element to ensuring the safety and security of these institutions, which house approximately 2.2 million adults. Thus, it is invaluable to explore work environment variables that contribute to their success. One area that has received scant attention is staff views of inmate medical care and their effect on job involvement and organizational commitment. This study focused on the effects of views concerning the proper handling of inmate infectious diseases, the quality of medical care provided to inmates, the timeliness of the responses to inmate medical needs, turnover of medical staff, and inmate medical privacy rights. Results indicate that proper handling of inmate infectious diseases and quality of medical care positively increase job involvement and organizational commitment.

Examining the association between work-family conflict and the work attitudes of job satisfaction and organizational commitment among Chinese correctional staff.

Considerable empirical research has shown that work-family conflict has a negative effect on the job satisfaction and organizational commitment of United States correctional staff. This study is the first to examine the effect of work-family conflict on job satisfaction and organizational commitment for staff at Chinese prisons. Findings from ordinary least squares (OLS) regression analyses indicated that strain-based conflict, behavior-based conflict and family-on-work conflict had negative effects on the job satisfaction of Chinese prison staff. Also, strain-based conflict and behavior-based conflict had negative effects on organizational commitment. Overall, the results support the conclusion that work-family conflict was generally perceived as stressful by Chinese prison staff and negatively impacted their job satisfaction and organizational commitment, as has been found among United States staff.

Exploring the Association Between Work-Family Conflict and Job Involvement.

Past research among U.S. correctional staff has found that work-family conflict has negative outcomes such as decreasing job satisfaction, decreasing organizational commitment, and increasing job stress. Little empirical research has addressed the association of the specific types of work-family conflict with job involvement. The present study contributes to the literature by separately analyzing the relationship of the four specific major types of work-family conflict (time-based conflict, strain-based conflict, behavior-based conflict, and family-on-work conflict) with job involvement among surveyed staff at two Chinese prisons. Job involvement varied by the type of work-family conflict. Specifically, time-based conflict and strain-based conflict had nonsignificant association with job involvement, but behavior-based and family-based conflicts had significant negative associations.

Pharmaceutical design and development of perfluorocarbon nanocolloids for oxygen delivery in regenerative medicine.

Perfluorocarbons (PFCs) have been investigated as oxygen carriers for several decades in varied biomedical applications. PFCs are chemically and biologically inert, temperature and storage stable, pose low to no infectious risk, can be commercially manufactured, and have well established gas transport properties. In this review, we highlight design and development strategies for their successful application in regenerative medicine, transplantation and organ preservation. Effective tissue preservation strategies are key to improving outcomes of extremity salvage and organ transplantation. Maintaining tissue integrity requires adequate oxygenation to support aerobic metabolism. The use of whole blood for oxygen delivery is fraught with limitations of poor shelf stability, infectious risk, religious exclusions and product shortages. Other agents also face clinical challenges in their implementation. As a solution, we discuss new ways of designing and developing PFC-based artificial oxygen carriers by implementing modern pharmaceutical quality by design and scale up manufacturing methodologies.

Quality by Design Approach Using Multiple Linear and Logistic Regression Modeling Enables Microemulsion Scale Up.

The development of pharmaceutical nanoformulations has accelerated over the past decade. However, the nano-sized drug carriers continue to meet substantial regulatory and clinical translation challenges. In order to address some of these key challenges in early development, we adopted a quality by design approach to develop robust predictive mathematical models for microemulsion formulation, manufacturing, and scale-up. The presented approach combined risk management, design of experiments, multiple linear regression (MLR), and logistic regression to identify a design space in which microemulsion colloidal properties were dependent solely upon microemulsion composition, thus facilitating scale-up operations. Developed MLR models predicted microemulsion diameter, polydispersity index (PDI), and diameter change over 30 days storage, while logistic regression models predicted the probability of a microemulsion passing quality control testing. A stable microemulsion formulation was identified and successfully scaled up tenfold to 1L without impacting droplet diameter, PDI, or stability.

When Domains Spill Over: The Relationships of Work-Family Conflict With Indian Police Affective and Continuance Commitment.

Policing is a stressful occupation that may give rise to work-family conflict (WFC). WFC arises when the work domain encroaches into the family domain, or vice versa, causing officers to become less attached to their job and the police organization. Using survey data collected from a sample of police officers in India, we examined the relationship between four dimensions of WFC (time-based, strain-based, behavior-based, and family-based WFC) and two dimensions of organizational commitment (continuance and affective). Family-based WFC was found to reduce continuance commitment, while strain-based WFC reduced affective commitment. Time-based, strain-based, and behavior-based WFC increased continuance commitment. We examined the implications of these findings for police policy makers and administrators. In addition, we also discussed our findings in the context of cross-cultural comparisons.

Writing Before Speaking Modifies Speech Production.

We investigated whether orthographic information influences speech production. We used a non-color-word version of the Stroop task in which participants had to ignore the presented words but name their ink color instead. In two experiments, we manipulated the phonological and orthographic relationships between the words and their ink color and the tasks' context by preactivating or not orthographic information. The relation between the first letter of the prime word and the first phoneme of the color name was phonological or orthographic and phonological or unrelated. In Experiment 1, only phonological information carried out by the prime word affected spoken naming; orthographic information did not help. In Experiment 2, speech production was influenced by orthographic information only after an initial writing task. This confirms that orthographic information can support speaking and that speech is sensitive to properties of the task's context, suggesting that orthographic information is coactivated online with phonological information.

Multiple linear regression applied to predicting droplet size of complex perfluorocarbon nanoemulsions for biomedical applications.

Multiple linear regression (MLR) modeling as a novel methodological advancement for design, development, and optimization of perfluorocarbon nanoemulsions (PFC NEs) is presented. The goal of the presented work is to develop MLR methods applicable to design, development, and optimization of PFC NEs in broad range of biomedical uses. Depending on the intended use of PFC NEs as either therapeutics or diagnostics, NE composition differs in respect to specific applications (e.g. magnetic resonance imaging, drug delivery, etc). PFC NE composition can significantly impact on PFC NE droplet size which impacts the NE performance and quality. We demonstrated earlier that microfluidization combined with sonication produces stable emulsions with high level of reproducibility. The goal of the presented work was to establish correlation between droplet size and composition in complex PFC-in-oil-in-water NEs while manufacturing process parameters are kept constant. Under these conditions, we demonstrate that MLR model can predict droplet size based on formulation variables such as amount and type of PFC oil and hydrocarbon oil. To the best of our knowledge, this is the first report where PFC NE composition was directly related to its colloidal properties and MLR used to predict colloidal properties from composition variables.

Development of Theranostic Perfluorocarbon Nanoemulsions as a Model Non-Opioid Pain Nanomedicine Using a Quality by Design (QbD) Approach.

Pain nanomedicine is an emerging field in response to current needs of addressing the opioid crisis in the USA and around the world. Our group has focused on the development of macrophage-targeted perfluorocarbon nanoemulsions as inflammatory pain nanomedicines over the past several years. We present here, for the first time, a quality by design approach used to design pain nanomedicine. Specifically, we used failure mode, effects, and criticality analysis (FMECA) which identified the process and composition parameters that were most likely to impact nanoemulsion critical quality attributes (CQAs). From here, we applied a unique combination approach that compared multiple linear regression, boosted decision tree regression, and partial least squares regression methods in combination with correlation plots. The presented combination approach allowed for in-depth analyses of which formulation steps in the nanoemulsification processes control nanoemulsion droplet diameter, stability, and drug loading. We identified that increase in solubilizer (transcutol) content increased drug loading and decreased nanoemulsion stability. This was mitigated by inclusion of perfluorocarbon oil in the internal phase. We observed negative correlation (R2 = 0.4357, p value 0.0054) between the amount of PCE and the percent diameter increase (destabilization), and no correlation between processing parameters and percent diameter increase over time. Further, we identified that increased sonication time decreases nanoemulsion drug loading but does not significantly impact droplet diameter or stability. We believe the methods presented here can be useful in the development of various nanomedicines to produce higher-quality products with enhanced manufacturing and design control.

Supervision Strategies and Their Correlates: An Empirical Study of Chinese Community Correctional Staff.

While there are different approaches to dealing with offenders sentenced to community corrections, the three major ones are law enforcement (surveillance), therapeutic (rehabilitation), and crime opportunity prevention. Using the study of U.S. community corrections staff by Miller as a guide, the current study examined the supervision strategy used by Chinese community corrections staff in the Hubei province of China. Chinese community corrections staff were more likely to use the therapeutic and crime opportunity prevention approaches than the law enforcement model. Predictors of each of the three offender supervision approaches differed. The results from Chinese staff were similar in many ways to that found among U.S. staff reported by Miller but differed in some areas.

Predictors of Death Penalty Views in China: An Empirical Comparison Between College Students and Citizens.

China's current Criminal Law has 46 death-eligible offenses, and China executes more people than any other country in the world. However, there is a lack of study of attitudes toward capital punishment for specific offenses, and no death penalty view comparison between college students and regular citizens in China was found. This study was taken to address these limitations. Using a sample of 401 respondents from Zhejiang, China, in 2016, the present study found that more than 72% of respondents favored the death penalty without any specification of crime types. Level of death penalty support differed by various specific crimes. As expected, relative to college students, general population citizens were more likely to support capital punishment. Both groups had the highest death penalty support for murder. The study also revealed similar and different reasons behind death penalty attitudes between college students and regular citizens.

An Exploratory Study of the Effects of Work Environment Variables on Job Satisfaction Among Chinese Prison Staff.

Job satisfaction has been linked to many positive outcomes, such as greater work performance, increased organizational commitment, reduced job burnout, decreased absenteeism, and lower turnover intent/turnover. A substantial body of research has examined how work environment variables are linked to job satisfaction among U.S. correctional staff; far less research has examined prison staff in non-Western nations, especially China. Using survey data collected from two prisons in Guangzhou, China, this study investigated the level of job satisfaction among prison staff and how personal characteristics (i.e., gender, tenure, age, and educational level) and work environment variables (i.e., perceived dangerousness of the job, job variety, supervision, instrumental communication, and input into decision making) affect job satisfaction. The findings from ordinary least squares regression equations indicated that the work environment variables explained a greater proportion of the variance in the job satisfaction measure than the personal characteristics. In the full multivariate regression model, gender was the only personal characteristic to have a significant association with job satisfaction, with female staff reporting higher satisfaction. Input into decision making and job variety had significant positive associations, whereas dangerousness had a significant negative relationship with job satisfaction.