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1.
Internist (Berl) ; 61(4): 411-415, 2020 Apr.
Article in German | MEDLINE | ID: mdl-32170331

ABSTRACT

Pneumonia and in particular aspiration pneumonia, is a common disease in geriatrics. These aspirations are often due to dysphagia, which is frequently first noticed in the context of a geriatric assessment. The reasons for dysphagia are manifold. In this geriatric department several patients have been detected in recent months in whom a Zenker diverticulum was the cause of recurrent aspiration pneumonia. The swallowing disorder was already apparent during the logopedic examination on admission to hospital. A supplementary fiber optic endoscopic evaluation of swallowing (FEES) revealed a postswallow hypopharyngeal reflux (PSHR), which is typical for a Zenker diverticulum. A supplementary contrast esophagography confirmed the findings. In the present case the treatment of choice was a myotomy with a flexible endoscope performed by gastroenterologists. After successful treatment, swallowing was again possible with no indications of penetration or aspiration in the FEES control. The case highlights the importance of logopedic diagnostics and treatment in geriatric patients with recurrent pneumonia. With the aid of early diagnostics it was possible to quickly recognize the finding of a PSHR that is typical for a Zenker diverticulum. The findings in this case could be clearly demonstrated based on the images of the FEES and contrast esophagography.


Subject(s)
Deglutition Disorders/physiopathology , Delirium , Diverticulum/diagnostic imaging , Esophagoscopy/methods , Pneumonia, Aspiration/physiopathology , Speech-Language Pathology/methods , Zenker Diverticulum/diagnostic imaging , Aged , Aged, 80 and over , Deglutition Disorders/complications , Deglutition Disorders/therapy , Fiber Optic Technology , Humans , Male , Myotomy , Pneumonia, Aspiration/etiology , Treatment Outcome , Zenker Diverticulum/physiopathology , Zenker Diverticulum/surgery
2.
Rev Sci Instrum ; 89(2): 023501, 2018 Feb.
Article in English | MEDLINE | ID: mdl-29495873

ABSTRACT

The Big Gravitational Spectrometer (BGS) takes advantage of the strong influence of the Earth's gravity on the motion of ultracold neutrons (UCNs) that makes it possible to shape and measure UCN spectra. We optimized the BGS to investigate the "small heating" of UCNs, that is, the inelastic reflection of UCNs from a surface accompanied by an energy change comparable with the initial UCN energy. UCNs whose energy increases are referred to as "Vaporized UCNs" (VUCNs). The BGS provides the narrowest UCN spectra of a few cm and the broadest "visible" VUCN energy range of up to ∼150 cm (UCN energy is given in units of its maximum height in the Earth's gravitational field, where 1.00 cm ≈ 1.02 neV). The dead-zone between the UCN and VUCN spectra is the narrowest ever achieved (a few cm). We performed measurements with and without samples without breaking vacuum. BGS provides the broadest range of temperatures (77-600 K) and the highest sensitivity to the small heating effect, up to ∼10-8 per bounce, i.e., two orders of magnitude higher than the sensitivity of alternative methods. We describe the method to measure the probability of UCN "small heating" using the BGS and illustrate it with a study of samples of the hydrogen-free oil Fomblin Y-HVAC 18/8. The data obtained are well reproducible, do not depend on sample thickness, and do not evolve over time. The measured model-independent probability P+ of UCN small heating from an energy "mono-line" 30.2 ± 2.5 cm to the energy range 35-140 cm is in the range 1.05±0.02stat×10-5-1.31±0.24stat×10-5 at a temperature of 24 °C. The associated systematic uncertainty would disappear if a VUCN spectrum shape were known, for instance, from a particular model of small heating. This experiment provides the most precise and reliable value of small heating probability on Fomblin measured so far. These results are of importance for studies of UCN small heating as well as for analyzing and designing neutron lifetime experiments.

3.
Phys Rev E ; 94(2-2): 026102, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27627424

ABSTRACT

We reply to the "Comment on 'Lifshitz-Matsubara sum formula for the Casimir pressure between magnetic metallic mirrors.' " We believe the comment misrepresents our papers, and fails to provide a plausible resolution to the conflict between theory and experiment.

4.
Phys Rev E ; 93(2): 022108, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26986289

ABSTRACT

We examine the conditions of validity for the Lifshitz-Matsubara sum formula for the Casimir pressure between magnetic metallic plane mirrors. As in the previously studied case of nonmagnetic materials [Guérout et al., Phys. Rev. E 90, 042125 (2014)], we recover the usual expression for the lossy model of optical response, but not for the lossless plasma model. We also show that the modes associated with the Foucault currents play a crucial role in the limit of vanishing losses, in contrast to expectations.

5.
Phys Rev Lett ; 115(3): 033201, 2015 Jul 17.
Article in English | MEDLINE | ID: mdl-26230791

ABSTRACT

We present a time-dependent quantum calculation of the van der Waals interaction between a pair of dissimilar atoms, one of which is initially excited while the other one is in its ground state. For small detuning, the interaction is predominantly mediated at all distances by the exchange of doubly resonant photons between the two atoms. We find that it presents both temporal and spatial oscillations. Spatially oscillating terms depend on the resonant frequencies of both atoms, while the frequency of the time oscillations is given by their detuning. We analyze the physical content of our findings and discuss to what extent previous conflicting stationary approaches provide compatible results. A proper account of causality is found essential in order to obtain the correct result.

6.
Article in English | MEDLINE | ID: mdl-25375456

ABSTRACT

We carefully reexamine the conditions of validity for the consistent derivation of the Lifshitz-Matsubara sum formula for the Casimir pressure between metallic plane mirrors. We recover the usual expression for the lossy Drude model but not for the lossless plasma model. We give an interpretation of this new result in terms of the modes associated with the Foucault currents, which play a role in the limit of vanishing losses, in contrast to common expectations.

7.
Phys Rev Lett ; 105(21): 210401, 2010 Nov 19.
Article in English | MEDLINE | ID: mdl-21231273

ABSTRACT

Disordered geometrical boundaries such as rough surfaces induce important modifications to the mode spectrum of the electromagnetic quantum vacuum. In analogy to Anderson localization of waves induced by a random potential, here we show that the Casimir-Polder interaction between a cold atomic sample and a rough surface also produces localization phenomena. These effects, that represent a macroscopic manifestation of disorder in quantum vacuum, should be observable with Bose-Einstein condensates expanding in proximity of rough surfaces.

8.
Phys Rev Lett ; 105(25): 250402, 2010 Dec 17.
Article in English | MEDLINE | ID: mdl-21231564

ABSTRACT

We measure the Casimir force between a gold sphere and a silicon plate with nanoscale, rectangular corrugations with a depth comparable to the separation between the surfaces. In the proximity force approximation (PFA), both the top and bottom surfaces of the corrugations contribute to the force, leading to a distance dependence that is distinct from a flat surface. The measured Casimir force is found to deviate from the PFA by up to 10%, in good agreement with calculations based on scattering theory that includes both geometry effects and the optical properties of the material.

9.
Appl Spectrosc ; 60(7): 729-36, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16854259

ABSTRACT

The application of mid-infrared laser spectroscopy to the reagent-free quantification of the concentration of glucose was investigated using cryogenically cooled lead salt lasers or, alternatively, quantum cascade lasers operating at room temperature. The concentration of glucose in aqueous solutions was quantified by means of fiber-based attenuated total reflection (ATR) spectroscopy (fiber-optical evanescent field analysis, FEFA) as well as fiber-based transmission spectroscopy. Both methods have the potential to be utilized by small fiber sensors, which can be inserted into the subcutaneous tissue in order to continuously measure the local concentration of glucose. In our in vitro experiments, noise-equivalent concentrations as low as 10 mg/dL were achieved. The mid-term stability of the measurement schemes was investigated by means of Allan variance analysis. Based on the research presented in this manuscript, an all-room-temperature measurement scheme using quantum cascade lasers, miniaturized fiber-optic sensors, and pyroelectric detectors appears well suited for the continuous monitoring of glucose concentrations at physiological levels.


Subject(s)
Biosensing Techniques/instrumentation , Blood Glucose Self-Monitoring/instrumentation , Hyperglycemia/diagnosis , Spectroscopy, Fourier Transform Infrared/instrumentation , Diabetes Mellitus/diagnosis , Electronics, Medical/instrumentation , Fiber Optic Technology , Humans , In Vitro Techniques , Lasers , Miniaturization/instrumentation , Models, Theoretical , Optical Fibers
10.
Phys Rev Lett ; 94(11): 110404, 2005 Mar 25.
Article in English | MEDLINE | ID: mdl-15903834

ABSTRACT

We show the influence of surface plasmons on the Casimir effect between two plane parallel metallic mirrors at arbitrary distances. Using the plasma model to describe the optical response of the metal, we express the Casimir energy as a sum of contributions associated with evanescent surface plasmon modes and propagative cavity modes. In contrast to naive expectations, the plasmonic mode contribution is essential at all distances in order to ensure the correct result for the Casimir energy. One of the two plasmonic modes gives rise to a repulsive contribution, balancing out the attractive contributions from propagating cavity modes, while both contributions taken separately are much larger than the actual value of the Casimir energy. This also suggests possibilities to tailor the sign of the Casimir force via surface plasmons.

11.
J Inherit Metab Dis ; 25(6): 522, 2002 Oct.
Article in English | MEDLINE | ID: mdl-12555947

ABSTRACT

Azelaic acid, sometimes found during analysis of Guthrie card blood samples, may be derived from the printing ink used to mark the spotting area.


Subject(s)
Dicarboxylic Acids/urine , Metabolism, Inborn Errors/urine , False Positive Reactions , Gas Chromatography-Mass Spectrometry , Humans , Infant, Newborn , Neonatal Screening , Reagent Kits, Diagnostic
12.
Phys Rev Lett ; 84(24): 5672, 2000 Jun 12.
Article in English | MEDLINE | ID: mdl-10991022
13.
Clin J Sport Med ; 8(1): 26-31, 1998 Jan.
Article in English | MEDLINE | ID: mdl-9448954

ABSTRACT

OBJECTIVE: Winconsin high school wrestlers were surveyed 1 year before (90W) and 2 years after (93W) a new program was implemented to restrict weight loss for competition. The Wisconsin wrestling minimal weight program (WMWP) included a minimal weight limit determined from percent body fat and a nutrition education program. DESIGN: A retrospective survey of wrestlers was conducted, with schools stratified to reflect school size and quality of the wrestling program. PARTICIPANTS: Respondents surveyed in 1990 included 713 wrestlers from 45 schools; 368 wrestlers from 29 of the same schools responded to an identical survey in 1993. MAIN OUTCOME MEASURES: Measures of weight-cutting practices, weight-loss methods, bulimic behaviors, and nutritional knowledge. RESULTS: The most weight lost (MWL), the weight lost to certify (WLC), the weekly weight cycled (WWC), the longest fast (LF), and the frequency of cutting weight (FCW) all decreased significantly (chi 2, p < 0.05) among 93W wrestlers compared with 90W wrestlers. The results for the 90W group are as follows: MWL, 3.2 kg +/- 2.6; WLC, 2.8 kg +/- 2.8; WWC, 1.9 kg +/- 1.5; LF, 20.5 hours +/- 17.2; FCW, 6.2 +/- 6.4. The results for the 93W group are as follows: MWL, 2.6 kg +/- 2.6; WLC, 2.4 kg +/- 2.9; WWC, 1.6 kg +/- 1.4; LF, 16.5 hours +/- 15.6; FCW, 4.7 +/- 6.7. Weight-loss methods, including restricting food or fluids and use of rubber suits, declined significantly (chi 2, p < 0.05). Wrestlers exhibiting more than one of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R)-related bulimic behaviors decreased by 11% (chi 2, p < 0.05), but those exhibiting all five (1.6%) remained the same. CONCLUSIONS: The results suggest that the WMWP appeared to reduce unhealthy weight-loss behaviors among high school wrestlers. Other states should be encouraged to institute similar programs as recommended by the American Medical Association and the American College of Sports Medicine.


Subject(s)
Weight Loss , Wrestling , Adult , Behavior , Bulimia/prevention & control , Bulimia/psychology , Health Surveys , Humans , Wisconsin , Wrestling/psychology
14.
Phys Rev A ; 54(6): 5243-5252, 1996 Dec.
Article in English | MEDLINE | ID: mdl-9914092
15.
Phys Rev Lett ; 77(4): 615-618, 1996 Jul 22.
Article in English | MEDLINE | ID: mdl-10062859
16.
Pediatrics ; 91(4): 826-31, 1993 Apr.
Article in English | MEDLINE | ID: mdl-8464675

ABSTRACT

Wrestlers are known for their extreme weight-cutting practices including fasting, food and fluid restriction, and dehydration. Using a stratified statewide survey, this investigation elucidated weight loss practices, nutritional knowledge, and bulimic behaviors among 713 high school wrestlers in Wisconsin. Results showed that 1.7% of the wrestlers answered questions consistent with all five criteria for bulimia nervosa, a rate higher than expected for adolescent males. An additional 43% exhibited weight-cutting practices similar to those of the wrestlers who met all bulimia nervosa criteria. The average wrestler lost 3.2 kg to compete, cycled 1.8 kg weekly, and fasted 20 hours prior to weigh-in. More extreme behaviors occurred among the 45% who met two or more bulimia nervosa criteria on their questionnaire; 19% frequently fasted, 25% restricted fluids, 34% used rubber suits, and 8% vomited. These results are comparable with data published over the past 20 years. Efforts to curtail these behaviors through regulations restricting weight loss coupled with sound nutritional information are warranted. Physicians and health professionals should be alert to potential eating disorders within this population.


Subject(s)
Bulimia/epidemiology , Wrestling/psychology , Adolescent , Adult , Humans , Male , Wisconsin/epidemiology
19.
J Neurochem ; 42(3): 798-809, 1984 Mar.
Article in English | MEDLINE | ID: mdl-6363628

ABSTRACT

Retinas were labeled in culture with [3H]glucosamine or [3H]leucine and [35S]sulfate and extracted sequentially with physiologically balanced saline and 4 M guanidine HCl. They were dialyzed into associative conditions (0.5 M NaCl) and chromatographed on agarose columns. Under these conditions, some of the proteoglycans were associated in massive complexes that showed low buoyant densities when centrifuged in CsCl density gradients under dissociative conditions (4 M guanidine HCl). Much of the label in these complexes was in molecules other than proteoglycans. Most of the proteoglycans, however, were included on the agarose columns, where they appeared to be constitutionally of low buoyant density. They resisted attempts to separate potential low buoyant density contaminants from the major proteoglycans by direct CsCl density gradient centrifugation or by the fractionation of saline or 8 M urea extracts on diethylaminoethyl-Sephacel. The diethylaminoethyl-Sephacel fractions were either subjected to CsCl density gradient centrifugation or were chromatographed on Sephacryl S-300, in both cases before and after alkaline cleavage, to confirm the presence of typical O-linked glycosaminoglycans. The medium and balanced salt extracts were enriched in chondroitin sulfate and other sulfated macromolecules, possibly highly sulfated oligosaccharides, that resisted digestion by chondroitinase ABC but were electrophoretically less mobile than heparan sulfate. Guanidine HCl or urea extracts of the residues were mixtures of high and low density proteoglycans that were enriched in heparan sulfate.


Subject(s)
Proteoglycans/isolation & purification , Retina/analysis , Animals , Centrifugation, Density Gradient , Chick Embryo , Electrophoresis, Cellulose Acetate , Glycosaminoglycans/isolation & purification , Molecular Weight , Radioisotope Dilution Technique , Sulfur Radioisotopes
20.
Acta Cardiol ; 36(3): 167-74, 1981.
Article in English | MEDLINE | ID: mdl-6973257

ABSTRACT

To determine the occurrence of inhibition of pacing by sensing of myopotentials, forty-five patients with predominant pacemaker driven heart rhythm were studied. In eleven patients with a bipolar lead system myopotential inhibition was never observed. In the remaining group (34 patients) with unipolar pacemakers myopotential inhibition was demonstrated in fifteen patients. Three of them were symptomatic, two severely. In forty new implants a silicone-rubber insulating sheath was placed against the muscular side of the pacemaker. In none of these patients myopotential inhibition could be demonstrated. The authors conclude that myopotential inhibition occurs frequently in unipolar ventricular inhibited pacemakers, and can be prevented by insulating the muscular side of the anodal surface.


Subject(s)
Heart Conduction System/physiopathology , Heart Ventricles/physiopathology , Pacemaker, Artificial , Electric Conductivity , Electromagnetic Fields , Heart Rate , Humans , Silicone Elastomers
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